The increasing prevalence of Artificial Intelligence (AI) in higher education underscores the necessity to explore its implications on ethical, social, and educational dynamics within the sector. This study aims to comprehensively investigate the impact of AI on higher education in Saudi Arabia, delving into stakeholders’ attitudes, perceptions, and expectations regarding its implementation. The research hones in on key facets of AI in higher education, encompassing its influence on teaching and learning, ethical and social implications, and the anticipated role of AI in the future. Employing a quantitative approach through an online survey questionnaire (N = 1113), this study reveals positive attitudes toward AI in higher education. Stakeholders recognize its potential to enhance teaching and learning, streamline administration, and foster innovation. Emphasis is placed on ethical considerations and guidelines for AI implementation, highlighting the imperative need to address issues such as privacy, security, and bias. Participants envision a future characterized by personalized learning experiences, ethically integrated AI, collaboration, and ongoing support for lifelong learning. Furthermore, the results illuminate the intricate interplay between AI usage, purposes, difficulties, and their impact on attitudes, perceptions, and future implications. Accordingly, the research underscores the necessity for a comprehensive understanding of AI integration, considering not only its technical aspects but also the ethical, social, and educational dimensions. By acknowledging the role of AI uses, AI usage purposes, and addressing associated difficulties, educational stakeholders can work towards harnessing the benefits of AI while ensuring responsible and effective implementation in teaching and learning contexts.