The computational modelling of the flange crushing phenomenon in cold-formed steel profiles is described in this paper, with particular emphasis to the development of shell finite element (SFE) models and performance of quasi-static analyses with an explicit integration scheme. Web crippling failure is widely recognised as the most relevant collapse mode of cold-formed steel members subjected to transverse concentrated loads. However, it has been experimentally and numerically observed that a somewhat different collapse mode may occur, due to the heavy stress concentrations stemming from the adoption of narrow bearing plates. This phenomenon, termed flange crushing, should not be confused with web crippling. Usually, the web crippling phenomenon is numerically investigated by means of non-linear static SFE models with an implicit integration scheme. In this study, SFE models are developed in ABAQUS code to study the flange crushing failure of a plain channel beam subjected to Internal Two Flange (ITF) loading conditions. These models are described in detail, as well as additional modelling concerns regarding quasi-static analyses and the explicit integration method. Different parameters are discussed in this article and the numerical results obtained are commented throughout. Such parameters include the (i) SFE type and mesh, (ii) load rate, mass scaling, adoption of smoothed displacement amplitude curves and control of inertial effects, (iii) contact and friction definitions, (iv) effects of forming cold-work and manufacturing process and (v) geometrical imperfections. Finally, the load–displacement response obtained with the quasi-static model and an equivalent non-linear static analysis are compared with the experimental test curves. It is concluded that very good results are achieved with the quasi-static approach, not only in terms of the ultimate load prediction, but also regarding the post-collapse load–deflection curve and the failure mechanism.