Twelve large-scale slab specimens and twenty-two companion push-out specimens were tested to study the behavior and capacity of composite slab joists consisting of cold-formed steel C-sections and concrete. Four shear transfer mechanisms, including surface bond, pre-fabricated bent-up tabs, pre-drilled holes, and self-drilling screws, were employed on the surface of the flange embedded in the concrete to provide shear transfer capacity. Results indicated that specimens employed with shear transfer enhancements showed a marked increase in strength and reduced deflection compared with those relying only on a natural bond between steel and concrete to resist shear. Of the three shear transfer enhancements investigated, bent-up tabs provided the best performance at both the strength and serviceability limit states, followed by drilled holes in the embedded flanges. The use of self-drilling screws resulted in the lowest strength increase. The correlation of shear transfer capacity of push-out specimens with the ultimate capacity of large-scale specimens indicated that the average experimental flexural capacity of the slab specimens was approximately 1.16 times the average predicted value based on push-out test results.