Cold Atmospheric Plasma Technology Research Articles

Coconut milk allergenicity: Insight into reducing the affinity of coconut globulin to immunoglobulin E by atmospheric cold plasma

Atmospheric cold plasma (ACP) presents a promising method for the sterilization of coconut milk and exhibits a modifying effect on coconut globulin (CG), the primary allergen in coconut milk. This study investigated the potential role of ACP treatment in mitigating the allergenic properties of coconut milk by examining changes in protein structure. ACP treatment induced structural alterations in CG, disrupting binding sites with immunoglobulin E (IgE). Consequently, this led to a reduction in the affinity between CG and IgE, evidenced by a decrease in Ka from 2.17 × 104/M to 0.64 × 104/M, thereby diminishing IgE-mediated allergic reactions. The findings from allergenic and cellular models further corroborated that ACP treatment decreased the allergenicity of CG by 55.18%, while inhibiting degranulation and the release of allergic mediators. This study presents an innovative methodology for producing hypoallergenic coconut milk, thereby expanding the applicability of ACP technology within the food industry.

In-package cold atmospheric plasma processing for shelf-life extension of gilthead seabream (Sparus aurata) fillets.

In-package cold atmospheric plasma (CAP) processing, which refers to the generation of CAP inside a sealed package, enables a local disinfecting reaction, allowing no post-process contamination and extending the shelf-life (SL) of perishable food products, such as fresh fish. In the present study, four in-package CAP treatments, differing in frequency and processing time, were applied on fresh gilthead seabream (Sparus aurata) fillets, prepacked in low-permeability pouches. Fish SL was evaluated during isothermal storage at 2°C, whereas untreated packaged fillets were used as control samples. The SL assessment of the fish fillets was based on microbial enumeration of total aerobic mesophilic count (TMC), total aerobic psychrotrophic count (TPC), Pseudomonas spp., Enterobacteriaceae, and lactic acid bacteria (LAB), pH measurement, determination of color and texture parameters, lipid oxidation, total volatile basic nitrogen (TVB-N) measurement, and sensory evaluation. All CAP treatments were effective against microbial inhibition in fish fillets, especially regarding TMC, TPC, and Pseudomonas spp., resulting in maximum reduction of 1.49, 1.24, and 1.43logCFU/g, respectively, compared to the control samples after 16 days of storage. However, minor effect was observed against Enterobacteriaceae and no effect against LAB. CAP processing did not affect the color and texture parameters of fish fillets, and TVB-N production was slightly reduced in CAP-treated samples; however, lipid oxidation was accelerated, especially at the more intense processing conditions, by a maximum of 75.5%. The results of the study indicated that in-package CAP processing could be effectively applied for inhibiting spoilage during refrigerated storage and extending SL of fresh fish fillets. PRACTICAL APPLICATION: In-package cold atmospheric plasma (CAP) processing was tested on gilthead seabream fillets, a highly perishable product with high commercial potential if its shelf-life can be extended through minimal processing. The food industry could benefit from in-package CAP technology as it is a cost effective nonthermal processing method while preventing post-processing contamination of the products. Although in-package CAP processing has not been extensively tested on fish, this study examined the quality and shelf-life of a highly perishable fish species, and the results could be further used as a reference for processing optimization of the CAP treatments.

Pathogens inactivation and preservation of Pacific white shrimp by atmospheric cold plasma treatment

Atmospheric cold plasma (ACP) efficacy in inactivating Listeria monocytogenes and Vibrio parahaemolyticus was investigated on fresh and frozen shrimp. ACP inactivation efficacy increased with treatment time (5–20 min) and treatment voltages (60–80 kV) due to increased reactive gas species. ACP yielded stronger pathogen inactivation on frozen versus fresh shrimp. ACP treatment at 80 kV for 30 min maximally reduced L. monocytogenes and V. parahaemolyticus by 0.94 and 1.26 log CFU/g on fresh shrimp and by 1.68 and 2.0 log CFU/g on frozen shrimp. During storage at 4 °C, ACP-treated shrimp exhibited slightly higher thiobarbituric acid reactive substances (TBARS) levels but overall improved quality attributes, including lower total viable count, total volatile basic nitrogen, and pH, as well as higher sensory scores compared to the controls. ACP also extended shrimp shelf-life by 2 days. Therefore, ACP holds significant potential for seafood disinfection and preservation. Industrial relevanceACP effectively reduced levels of Listeria monocytogenes and Vibrio parahaemolyticus on both fresh and frozen shrimp with greater inactivation effects on frozen shrimp. In addition to enhancing microbial safety, ACP also improved shrimp quality and extended shelf-life. ACP could readily be coupled with packaging technology and bio preservatives to enhance its efficacy. This research provides a foundation for the eventual industrial adoption of ACP technology to benefit both consumers through reduced pathogen risks, and seafood processors through improved product safety, quality, and shelf-life.

The application of cold atmospheric plasma technology in the brain: The potential role of reactive species in neuroprotection effects of plasma

The application of cold atmospheric plasma technology in the brain: The potential role of reactive species in neuroprotection effects of plasma

Effect of the Cold Atmospheric Plasma Technology for Treatment the Cancer Diseases in the Human: A literature Review

CAP is a form of plasma with a temperature below 104°F at the application site. There are a variety of techniques for producing CAP, including Atmospheric Pressure Plasma Jet, Dielectric Barrier Discharge, and plasma needle and pencil. Multiple gases can produce CAP, including Helium, Heliox, Nitrogen, Argon, and air. Due to CAP's ability to deactivate organisms, cause cell separation, and kill cancer cells, researchers are interested in identifying dental and oncological applications for the compound. CAP is an ionized gas at 25 Co; it produces ROS and RNS due to several factors such as U.V., ray, heat, and power electric effects. Plasma is a matter at (fourth state) formed at low pressure or high temperature. Often, it is described as an ionized gas produced by the polyatomic fragmentation or the subtraction of electrons from monatomic gas shells. CAP has an antitumor effect. The current study aims to shed light on CAP technology, its definition, types, general applications, and their applications in treating human cancer. CAP was effective in treating cancer and eliminating tumor cells. CAP may have a place in the therapy of cancer. CAP used for cancer therapy has many advantages as a therapeutic method due to its effects of high selectivity, non-toxicity, combination potential, and adaptability. CAP eradicates cancer cells and uses this technique as a clinical therapeutic option that is effective and safe.

Cold atmospheric plasma: a sustainable approach to inactivating viruses, bacteria, and protozoa with remediation of organic pollutants in river water and wastewater

Innovative technologies are needed to enhance access to clean water and avoid waterborne diseases. We investigated the performance of cold atmospheric plasma (CAP), a clean and sustainable approach for microbial inactivation and total organic carbon (TOC) degradation in environmental water. Water matrices played a crucial role in the performance of CAP efficacy; for example, complete removal of ɸX174 from dH2O required 1 min of treatment, while ɸX174 reductions of ~ 2log10 and 4log10 were obtained after 10 min of CAP exposure in river water and wastewater samples, respectively. Similarly, after 10 min of CAP treatment, bacterial concentrations decreased by 3 log10 and 4 log10, in river and wastewater samples, respectively. In contrast, after 30 s of contact time, a 4 log10 reduction of bacteria was accomplished in dH2O. Complete removal of Acanthamoeba from dH2O was found after 30 min of CAP treatment, whereas it was not removed from surface water or wastewater at the same exposure time. Additionally, the approach successfully reduced TOC, and the degradation kinetics of TOC were represented by pseudo-first-order. CAP showed higher rates of TOC degradation in the final effluent of the wastewater treatment plant compared to surface water. The difference in CAP performance between river water and wastewater could be attributed to the bulk structure of humic acids in river water compared to small organic byproducts in the final effluent of WWTP. Overall, the findings reported here support the idea that CAP holds promise as a sustainable solution for controlling pathogens, removing organic water pollution, and integrating with traditional purification processes. Low-cost systems may advance CAP technology and increase its widespread use.

Effect of atmospheric pressure non-thermal pin to plate cold plasma on structural and functional properties of pea protein isolate

Atmospheric Cold Plasma (ACP) has a proven track record for its non-thermal, minimal processing technology. The effects of ACP technology on the physicochemical and functional properties of Pea Protein Isolate (PPI) solutions. The results indicated significant changes in various properties of the PPI sample. The percentage of soluble protein increased by 66.94 % in the highest treatment compared to the untreated sample. A similar trend was observed for Emulsifying Activity and Emulsifying Stability, which showed significant increases of 25.27 % and 10.80 %, respectively. Foaming capacity and stability also increased by 57.28 % and 6.06 %, respectively. Additionally, beneficial changes in rheological behavior were observed, with increased viscosity during the cooling period from 95 °C to 40 °C, which has potential benefits for various food applications. Differential Scanning Calorimetry (DSC) results indicated that ACP treatment rearranged the conformation of PPI. The FTIR spectrum confirmed changes in the secondary structure, particularly in the amide I region (1600 - 1700 cm−1), following ACP treatment. This study demonstrates that ACP treatment can successfully modify the functionality of PPI.

Understanding the mechanisms of action of atmospheric cold plasma towards the mitigation of the stress induced in molds: The case of Aspergillus chevalieri

Aspergillus chevalieri is a xerophilic/xerotolerant fungi affecting dried food products. In this study the ability of non-thermal cold atmospheric plasma (CAP) at high power density (NOx) to affect biological process inducing the stress responses of A. chevalieri species exposed for 5 min (5’CAP-NOx) and 30 min (30’CAP-NOx) were analysed at 0, 1, 6, 12 and 48-h post treatment (hpt). At 48 hpt with 30’CAP-NOx, 84% of fungal growth reduction was observed. The membrane integrity estimated by confocal investigation after carboxyfluorescein diacetate/propidium iodide staining showed the dead surface mycelium layers exposed to the treatments. Reverse transcription-quantitative real-time PCR revealed an early downregulation, at 0 hpt, followed by upregulation or recovery starting to 1 hpt, of selected key genes involved in fungal stress responses. The cellular response to stress was confirmed by mycelial glutathione accumulation in the early phase after both CAP-NOx treatments, at 0 and 1 hpt, followed by the strong glutathione reduction at 12 and 48 hpt using 30’CAP-NOx treatment. The ability of A. chevalieri to modulate metabolic profile according to treatments was underlined by volatilome investigation, which mainly involved lipid metabolism. This work highlighted the adaptative response mechanisms of A. chevalieri to overcome the CAP-NOx treatment. Industrial relevanceThe application of cold atmospheric plasma (CAP) technology to avoid microbial growth in foods is considered of high interest. Utilization of CAP technology, a nonthermal technique, is encouraged because of its efficiency in maintaining natural aroma and flavor and product shelf-life. Regarding the management of Aspergillus chevalieri, the developments in mechanistic insights indicated that cold plasma affected several targets in fungal cells and was a successful tactic when employed to stop the selection of resistant fungal strains.

Reduction of microbial population of fresh vegetables (carrot, white radish) and dried fruits (dried fig, dried peach) using atmospheric cold plasma and its effect on physicochemical properties

Non-observance of hygiene principles during storage causes excessive growth of microorganisms in these products and the return of export products to the manufacturer. The purpose of this research is to examine the antimicrobial effects of the jet cold plasma device and its impact on the physicochemical and sensory characteristics of a carrot, white radish, dried fig, and dried peach. For this purpose, the samples were inoculated with Escherichia coli O157:H7, Enterococcus faecalis, and Aspergillus niger. Then samples were treated with atmospheric cold plasma in the form of a jet probe and DC pulse source with 17 KV and 2.26A for 0, 3, 6, 9, and 12 min. The results showed that the rate of inactivation of microorganisms increases with increasing exposure time to atmospheric cold plasma. The maximum reduction of the microbial load was observed at 17 kV and 12 min. The resistance of microorganisms in dried fig and dried peach was higher than in carrot and white radish due to lower humidity. Also, A. niger showed the highest resistance to cold plasma compared with E. coli O157:H7, and E. faecalis. By comparing the average indices of a, and b, no significant change was observed between the treated and the control samples (p > 0.05). The texture structure remained intact after plasma application, and the plasma had no destructive effect on the texture. The samples treated with cold plasma did not show a significant effect on the physicochemical and sensory characteristics of different food products. Therefore, atmospheric cold plasma technology can be used as an efficient maintenance technique to enhance the shelf life of food products.

Effect of low current cold atmospheric plasma on grains surface structure and water absorption capacity

The use of preparatory electrophysical methods of influencing food raw materials is one of the main trends in the development of innovative processes and technologies in the food and processing industry. Based on the physical effect of electron emission from a thermal emission source, a cold atmospheric plasma (CAP) was obtained, which was successfully applied to the grain material. Physical characteristics and evolution of low-temperature atmospheric plasma were considered as the main methods of analysis of electrophysical effects. To assess the effect of low-temperature plasma on grain material, measurements of water absorption capacity and analysis of surface modification by electron scanning microscopy were carried out. It has been experimentally established that CAP treatment contributes to a more intensive process of water absorption due to changes in the surface structure of the grain material. The total duration of the process of water absorption of grain material after processing of CAP decreased by more than three times until the equilibrium moisture content was reached. Scanning electron microscopy has shown that the processing of CAP leads to the appearance of a fine-mesh structure of the surface of the grain material. The effect of CAP treatment leads to modification of the seed surface, which consists in the manifestation of a fine-meshed structure on the surface of the seeds. Taking into account the advantages of CAP technology, namely the absence of the need for vacuuming and short processing time, the technology has a high practical potential.

Inactivation of pectinmethylesterase in fresh orange juice by cold atmospheric plasma technology: A kinetic study

Preservation of fruit juices requires the inactivation of natural endogenous enzymes, such as pectinmethylesterase (PME). Within this work, cold atmospheric plasma (CAP), and in particular a dielectric barrier plasma jet fed with helium gas, was demonstrated to effectively inactivate PME of freshly squeezed orange juice in short treatment times (2–30 min). By a combination of temperature measurements and a multidimensional heat transfer model, the temperature profile of the whole sample during plasma treatment was extracted. It was found that the thermal phenomena were not a driving factor for PME inactivation. Plasma treatment of orange juices resulted in inactivation of 55–80% of PME with <5.0% of PME inactivation caused by the temperature increase from 20 to 90 °C. The Weibull distribution model compared to the first-order fractional, the sigmoidal logistic and the Hulsheger's kinetic models was found to better describe mathematically (R2 > 0.99; Af = 1.002–1.052) the effect of CAP processing on residual PME activity. Multi-parameter equation fits allowed the prediction of residual PME activity as a function of the applied voltage, helium flow, and treatment time. Generally, higher voltages and lower helium flows applied led to higher PME inactivation rates in fresh orange juice.

Application of NaCl in Cold Atmospheric Plasma Jet and Plasma-Activated Solution to Enhance Virus Inactivation

Viruses are serious pathogenic contaminants that gravely threaten human health. There is an urgent need for environment-friendly and novel disinfection methods to inactivate various viruses. In this study, we applied the technique of cold atmospheric plasma (CAP) for virus disinfection. Particularly, we utilized the cold atmospheric plasma jet (CAPJ) and the plasma-activated solution (PAS) approaches for the treatment of bacteriophage MS2, and we added NaCl in the treatment system to enhance the disinfection efficiency. The inactivation effects under different CAPJ-PAS conditions using various plasma working gases were investigated. Also, the involved inactivation mechanisms due to respective active species were scrutinized. Our results showed that the addition of NaCl could considerably enhance the virus inactivation efficiency in the air/oxygen-CAPJ-PAS treatment, and during the direct CAPJ treatment, the primary inactivation factors were attributed to &amp;#183;OH, &lt;sup&gt;1&lt;/sup&gt;O&lt;sub&gt;2&lt;/sub&gt;, ONOOH and ClO&lt;sup&gt;-&lt;/sup&gt;, while for the indirect PAS treatment, the major inactivation contributors stemmed from &lt;sup&gt;1&lt;/sup&gt;O&lt;sub&gt;2&lt;/sub&gt; and ClO&lt;sup&gt;-&lt;/sup&gt;. This work therefore demonstrates the usefulness of NaCl in the CAPJ-PAS treatment in the virus inactivation and offers new perspectives on the application of CAP technology in disinfection of viruses.

The impact of cold plasma innovative technology on quality and safety of refrigerated hamburger: Analysis of microbial safety and physicochemical properties

Atmospheric cold plasma (ACP) is an innovative non-thermal decontamination technology that is considered a great alternative to conventional preservation methods. Most importantly, improving microbial safety along with maintaining the sensory and quality properties of the treated foods, especially for perishable products. Hence, this study aimed to investigate the antimicrobial effects of novel dielectric barrier discharge (DBD) and Jet cold plasma systems and their impact on the physicochemical, color, and sensory properties of refrigerated hamburger samples. In the current study, hamburger samples were inoculated with Staphylococcus aureus, Escherichia coli, Molds and Yeasts microbial suspension (~106 CFU/mL), and then were treated with argon (Ar), helium (He), nitrogen (N), and atmosphere (Atm) gases at different times (s) (0, 30, 60, 90, 180, 360). Similarly, uninoculated samples were considered for total viable count (TVC) testing. The results exhibited that plasma system type, gas type, and treatment time had a significant antimicrobial effect with a microbial reduction ranging from 0.01 to 2 log CFU/g and 0.04–1.5 log CFU/g for DBD and Jet plasma systems, respectively. Also, a treatment time longer than 90 s for DBD and 180 s for jet resulted in a significant reduction in microbial count. The ability of atmospheric cold plasma to inactivate tested foodborne pathogenic bacteria (E. coli and S. aureus) was stronger than other gases because the concentration of O3 and NO gases in atmospheric plasma is higher than other used plasma gases. Surface color measurements (L*, a* and b*) of samples in both methods (DBD and Jet) were not significantly affected. Moreover, samples treated with various plasma gases have indicated insignificant oxidation changes (Thiobarbituric acid assay). These outcomes can assist to reduce microbial contamination and oxidation of hamburgers as a high-consumption and perishable product using ACP technology. Owing to the non-thermal nature of ACP, samples treated with ACP have exhibited no or least effects on the physical, chemical, and sensory features of various food products. As a result, cold plasma innovative technology can be proposed and used as an efficient preservative method to increase the shelf life of food products.

Applications of atmospheric cold plasma in agricultural, medical, and bioprocessing industries.

Atmospheric cold plasma (ACP) is a nonthermal technology that is extensively used in several industries. Within the scopes of engineering and biotechnology, some notable applications of ACP include waste management, material modification, medicine, and agriculture. Notwithstanding numerous applications, ACP still encounters a number of challenges such as diverse types of plasma generators and sizes, causing standardization challenges. This review focuses on the uses of ACP in engineering and biotechnology sectors in which the innovation can positively impact the operation process, enhance safety, and reduce cost. Additionally, its limitations are examined. Since ACP is still in its nascent stage, the review will also propose potential research opportunities that can help scientists gain more insights on the technology. KEY POINTS: • ACP technology has been used in agriculture, medical, and bioprocessing industries. • Chemical study on the reactive species is crucial to produce function-specific ACP. • Different ACP devices and conditions still pose standardization problems.

Role of cold atmospheric plasma in microbial inactivation and the factors affecting its efficacy

The rise in multidrug-resistant pathogens and biofilms has become a significant issue to address. In the rise of the hour, various innovating technologies are being used to combat these deadly pathogens. One of the emerging technologies is cold atmospheric plasma (CAP) which could bring a revolution to this aspect. The antimicrobial property of CAP makes it a powerful tool in the inactivation of multidrug-resistant pathogens and biofilms. This review paper emphasizes how the antimicrobial efficacy of CAP is affected by the types of the devices, operating gas composition and flow rate, variation of source frequency, voltage and power, exposure distance, treatment time, initial concentration of microorganism suspension, and growth media and nature of target microorganisms. Further, the role of various CAP agents i.e., reactive species, charged particles, UV radiation, and electric field in the inactivation mechanism has been reviewed. A brief idea of some of CAP technology's prospects and its effectiveness has been discussed at the end. Overall, the content of this review provides a global thought on the influence of CAP parameters on drug-resistant pathogens and biofilms, which will aid researchers in this field.

Cold atmospheric plasma differentially affects cell renewal and differentiation of stem cells and APC-deficient-derived tumor cells in intestinal organoids

Cold atmospheric plasma (CAP) treatment has been proposed as a potentially innovative therapeutic tool in the biomedical field, notably for cancer due to its proposed toxic selectivity on cancer cells versus healthy cells. In the present study, we addressed the relevance of three-dimensional organoid technology to investigate the biological effects of CAP on normal epithelial stem cells and tumor cells isolated from mouse small intestine. CAP treatment exerted dose-dependent cytotoxicity on normal organoids and induced major transcriptomic changes associated with the global response to oxidative stress, fetal-like regeneration reprogramming, and apoptosis-mediated cell death. Moreover, we explored the potential selectivity of CAP on tumor-like Apc-deficient versus normal organoids in the same genetic background. Unexpectedly, tumor organoids exhibited higher resistance to CAP treatment, correlating with higher antioxidant activity at baseline as compared to normal organoids. This pilot study suggests that the ex vivo culture system could be a relevant alternative model to further investigate translational medical applications of CAP technology.

Impact of Cold Atmospheric Plasma (CAP) Treatments on the Oxidation of Pistachio Kernel Lipids.

Cold atmospheric plasma (CAP) is a non-thermal technology that could be applied for food decontamination from both biological (microorganisms) and chemical (pesticides, food allergens, mycotoxins) contaminants, thanks to the production of reactive species (RS). However, RS could also promote the onset and the progress of food lipid oxidation, which may limit the quality and acceptability of the final products. The aim of this work was to assess the oxidation degree of pistachio kernels after treatment in a surface dielectric barrier discharge (SDBD). Two different operative conditions for CAP generation were investigated, resulting in the production of high (800 ppm) or low (300 ppm) concentrations of ozone. Limited amounts of hydroperoxides (3.00–4.22 mEq O2/kg), thiobarbituric acid reactive substances (TBARS, 0.072–0.600 mg TEP/g oil), and phytosterol oxidation products (POPs, 14.43–17.20 μg/g) were observed in lipids of both control and plasma processed pistachios. Plasma treatments did not significantly affect the total fatty acid composition and the amounts of identified unsaponifiable matter constituents (4-desmethylsterols, 4,4-dimethylsterols, 4-methylsterols), except for an unexpected significant increase of γ-tocopherol content in extracted oils. These findings contribute to gaining further knowledge for the scale-up of CAP technology to industrial processing.

Cold atmospheric plasma technology for removal of organic micropollutants from wastewater\u2014a review

Water bodies are being contaminated daily due to industrial, agricultural and domestic effluents. In the last decades, harmful organic micropollutants (OMPs) have been detected in surface and groundwater at low concentrations due to the discharge of untreated effluent in natural water bodies. As a consequence, aquatic life and public health are endangered. Unfortunately, traditional water treatment methods are ineffective in the degradation of most OMPs. In recent years, advanced oxidation processes (AOPs) techniques have received extensive attention for the mineralization of OMPs in water in order to avoid serious environmental problems. Cold atmospheric plasma discharge-based AOPs have been proven a promising technology for the degradation of non-biodegradable organic substances like OMPs. This paper reviews a wide range of cold atmospheric plasma sources with their reactor configurations used for the degradation of OMPs (such as organic dyes, pharmaceuticals, and pesticides) in wastewater. The role of plasma and treatment parameters (e.g. input power, voltage, working gas, treatment time, OMPs concentrations, etc.) on the oxidation of various OMPs are discussed. Furthermore, the degradation kinetics, intermediates compounds formed by plasma, and the synergetic effect of plasma in combination with a catalyst are also reported in this review.Graphic

Effectiveness of atmospheric cold plasma technology on physicochemical and functional characteristics of ST25 fragrant rice (Oryza sativa L.) flour

Vietnam is one of the leading rice export countries in the world. ST25 fragrant rice (Oryza sativa L.) won the top prize for best rice in the world in 2019 and the second at World's Best Rice Contest 2020. Plasma has been considered as an innovative food processing technology. The aim of this study demonstrated the impact of time (4, 6, 8, 10, 12 min), power (160, 180, 200, 220, 240 W) and oxygen flow rate (0.2, 0.4, 0.6, 0.8, 1.0 ml/min) to the physicochemical and functional qualities of ST25 fragrant rice flour. Results showed that under plasma treatment time at 10 minutes, power 200 W, oxygen flow rate 0.8 ml/min, the amylose content (16.67±0.01 %), pasting temperature (83.21±0.02 oC), water absorption index (14.54±0.00 gm/gm sample), water solubility index (10.31±0.02 gm/100 gm sample), swelling power (14.96±0.00 gm/gm sample) were recorded. Under plasma treatment, surface of the ST25 fragrant rice flour became more hydrophilic to absorb more water resulting to shorter cooking time. Plasma treatment provides environmentally friendly processing of rice grain to limit pesticide abuse towards ecological farming.

PLASMA AIDS DENTAL BONDING

Here Peter Swanson, managing director of Intertronics, discusses cold atmospheric plasma technology and its applications in dental technology.