Periods are algebraic integrals, extending the class of algebraic numbers, and playing a central, dual role in modern Mathematical-Physics: scattering amplitudes and coefficients of de Rham isomorphism. The Theory of Periods in Mathematics, with their appearance as scattering amplitudes in Physics, is discussed in connection with the Theory of Motives, which in turn is related to Conformal Field Theory (CFT) and Topological Quantum Field Theory (TQFT), on the physics side. There are three main contributions. First, building a bridge between the Theory of Algebraic Numbers and Theory of Periods, will help guide the developments of the later. This suggests a relation between the Betti-de Rham theory of periods and Grothendieck’s Anabelian Geometry, towards perhaps an algebraic analog of Hurwitz Theorem, relating the algebraic de Rham cohomology and algebraic fundamental group, both pioneered by A. Grothendieck. Second, a homotopy-homology refinement of the Theory of Periods will help explain the connections with quantum amplitudes. The novel approach of Yves Andre to Motives via representations of categories of diagrams, relates from a physical point of view to generalized TQFTs. Finally, the known “universality” of Galois Theory, as how symmetries “grow”, controlling the structure of the objects of study, is discussed, in relation to the above several areas of research, together with ensuing further insight into the Mathematical-Physics symbiosis. To better understand and investigate Kontsevich-Zagier conjecture on abstract periods, the article ponders on the case of algebraic Riemann Surfaces representable by Belyi maps. Reformulation of cohomology of cyclic groups as a discrete analog of de Rham cohomology and the Arithmetic Galois Theory will provide a purely algebraic toy-model of the said algebraic homology/homotopy group theory of Grothendieck as part of Anabelian Geometry. The corresponding Platonic Trinity 5,7,11/TOI/E678 leads to connections with ADE-correspondence, and beyond, e.g. Theory of Everything (TOE) and ADEX-Theory. In perspective of the “Ultimate Physics Theory”, quantizing “everything”, i.e. cyclotomic quantum phase and finite Platonic-Hurwitz geometry of qubit frames as baryons, could perhaps be “The Eightfold (Petrie polygon) Way” to finally understand what quark flavors and fermion generations really are.