3D printing is now being applied in various research areas due to its ability to produce highly complex parts whenever needed. This is highly helpful in the fields of robotics; radiation environment monitoring and space applications where stand-alone equipment are usually required. In this work, FDM 3D-printed polycarbonate acrylonitrile butadiene styrene (PCABS) samples were subjected to 1 kGy to 9 kGy of gamma irradiation from a Cobalt-60 irradiator. Parameters such as infill density and dose rate were modified to determine the best setting to improve the mechanical characteristics of the 3D-printed thermoplastic. Results show that samples with lower infill density obtain higher ultimate strength when exposed to higher doses of radiation.