Coat Color Dilution Research Articles

Genetic control of cross-reactive cytotoxic T-lymphocyte responses to a BALB/c tumor.

Using a segregation analysis we have determined that the cross-reactive response to the DBA/2 tumor P815 by CTL from BALB/c mice immunized with a BALB/c plasmacytoma (MOPC-167) is controlled by a single gene. The gene responsible is closely linked to the dilute coat color locus on chromosome 9. In contrast, the cross-reactive response to the DBA/2 tumor L5178Y by DBA/2 anti-MOPC-167 CTL appears to be controlled by two or more genes.

A allele necessary for dilute coat color in horses.

A allele necessary for dilute coat color in horses.

Dilute locus and audiogenic seizures in mice.

Evidence which indicates a positive relationship between susceptibility to audiogenic seizure and dilute coat color in mice is presented, and a possible mechanism for this relationship is discussed.

The effect of the coat colour dilution gene on body size in the mouse

The effect of the coat colour dilution gene on body size in the mouse

A mosaic (dark-eyed intense—pink-eyed dilute) coat colour of the house mouse

Two cases of mosaic (dark-eyed intense—pink-eyed dilute) pelage patterns are reported in the house mouse. The unusual colour was not inherited by descendants. A direct correlation between the mosaic pattern of the coat and the pattern of piebald white-spotting in this strain of mice was observed. Aberrant chromosome division in somatic tissue is suggested as an explanation of these mosaics.