Stratigraphic and structural interpretative studies have been carried out within the paralic sequence of Agbada Formation in the Niger Delta Basin. The method of study involved integrating sequence stratigraphic techniques with well logs, biostratigraphy, and 3D regional seismic data obtained from several producing fields in the Coastal Swamp depobelt of the onshore Niger Delta Basin. This was targeted at establishing regional sequence stratigraphic and structural framework from well log correlation and seismic mapping so as to better define hydrocarbon leads. Well log correlation using stratigraphic bounding surfaces such as maximum flooding surfaces (MFSs) and sequence boundaries (SBs) indicates that the stratigraphic package was deposited within the Middle to Late Miocene (8.5 to 12.1 Ma) age. Recognized depositional sequences revealed differential thickening and thinning of the associated system tracts (lowstand system tract (LST), transgressive system tract (TST), and highstand system tract) (HST)). This observed stratal behavior has been attributed to the influence of syndepositional tectonic structures that characterize the Coastal Swamp depobelt, which lies within the extensional zone. Flattening of MFSs at various ages indicates observable basinward shift of the depositional center. The genetic units of LST and HST serve as good hydrocarbon reservoir whereas HST and TST constitutes mainly the source and seal packages rocks in the area. Structural interpretation revealed the occurrence of simple/faulted rollover anticline, collapsed crest, regional hanging wall and footwall, horst block, and subdetachment fault structural styles that constitute the key hydrocarbon entrapment mechanisms. Structural top maps show fault-dependent closures which dominate the extensional zone, which could form possible hydrocarbon leads and prospects that should be targeted during exploration studies for development.