Olfactory enrichment of domestic cats using certain herbs can re-establish naturalistic feline behaviour and reduce inactivity. The role of Acalypha indica on such behavioural changes in domestic cats were assessed in this study. Closed-circuit television cameras were used to minimise human interference and observer effects on test subjects. Cats were individually tested against each scent in a closed empty pre-acclimatised enclosure. The ethogram for the study included 7 behaviours: sniffing, chewing, licking, face rubbing, rolling, lying, and holding and two time-intervals: total interaction time and lag period. The experiment was conducted in two phases. First, cats’ behaviours towards whole plants of Laporea interrupta (C1 =control-1), A. indica and Nepeta cataria powder was assessed. Secondly, cats’ behaviour towards liquids: fresh root- distilled water extract (FW), dried root-Ethanol extract (DE) and Ethanol/distilled water extract (EW) of A. indica; N. cataria spray (CS) and distilled water (C2 =control-2) were tested. Of the 37 cats tested, 65.6% showed olfaction reactions towards A. indica or its extractions, while 37.5% of cats reacted towards N. cataria. Pair-wise comparison of A. indica and C1 were statistically significant for all the tested parameters, whereas N. cataria and C1 showed a statistically significant difference only for lag-period (p = 0.039) and face-rubbing (p = 0.022). Gender and age of cats showed no statistically significance for any behavioural reaction. Behaviour responses differed between A. indica and N. cataria (chewing 95.24% and 25.00%; rolling: 58.33% and 10.31% respectively) while similar behavioural patterns were noted for A. indica and FW. Comparison of EW, CS, DE, FW with C2 revealed that only FW had a significant statistical difference for all tested behaviours, while DE showed a significant difference for total interaction time (p = 0.013) and sniffing (p = 0.007). In conclusion, the longer and intense response to A. indica by the cats suggests its utility as an environment enrichment agent.