Abstract Introduction: Existing protocols for clinical trials are typically slow and error-prone due to lack of informatics tools for sharing and accessing clinical data in real time. There is an increasing pressure on clinical trial laboratories to change the way clinical research is performed so as to minimize costs and speed up R&D, which in turn will produce better and faster outcomes. Cloud-based technologies are emerging as one of the most viable options for streamlining the heavily regulated clinical research processes. Description: Cloud-based software tools such as laboratory information management systems (LIMS) are much more capable than traditional paper-based or desktop tools for accelerating a clinical trial life cycle. Cloud-based LIMS enhance collaboration between sponsors and investigators, enabling more timely and accurate sharing of information with pharmaceutical companies. Summary: Many sponsors are now adopting cloud-based LIMS for conducting clinical trials. The onus is on service providers to keep pace with the demands of the industry, comply with the regulatory framework and at the same time deliver value to CROs and testing labs by reducing costs and maintaining efficiency. Conclusion: CloudLIMS.com has developed a cloud based software called CloudLIMS Lite for managing clinical research workflows to provide a cost effective solution to the clinical research industry. Being on the cloud, CloudLIMS Lite facilitates users to access and share data in real time, across multiple laboratories in different geographical locations and adhere to the regulatory framework. This in turn improves their operational efficiency. CloudLIMS Lite uses 256-bit AES encryption SSL protocol, thereby enabling secure data transmission. CloudLIMS Lite deploys a separate database layer for each of its customers making it impossible for any third party to view or access data. Citation Format: Arun Apte, Shonali Paul, Aditi Gade, Carolyn Compton. Accelerating clinical research using cloud technology [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 2606. doi:10.1158/1538-7445.AM2017-2606