Clinical Practice Guidelines For Diagnosis Research Articles

ED08.01 Surgery of Early-Stage NSCLC

ED08.01 Surgery of Early-Stage NSCLC

MTE27.01 Treatment of Lung Cancer Patients with Poor Performance Status

MTE27.01 Treatment of Lung Cancer Patients with Poor Performance Status

ED04.01 Surgery in Bronchopulmonary Typical and Atypical Carcinoids

ED04.01 Surgery in Bronchopulmonary Typical and Atypical Carcinoids

Reply to Early colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Laparoscopic surgery for the treatment of right colon cancer has rapidly evolved over the past few years. This procedure is considered as feasible and effective in terms of short-term and long-term outcomes. Laparoscopic right colectomy (LRC) is performed by a small number of surgeons and, in most of cases, it was performed with an extracorporeal anastomosis.1 The recent ESMO guidelines with a Level of Evidence (LE) IV reported that for right-sided colonic cancers, the benefits of laparoscopic approach are less obvious since anastomosis must be hand sewn, which requires a laparotomy.2 The current state of the art for the treatment of the right colon cancers as reported by Fabozzi et al.3 in their papers, by right laparoscopic colectomy with intracorporeal anastomosis despite the technical challenging. However, in the past few years, many studies comparing the intracorporeal anastomosis (IA) versus the extracorporeal anastomosis (EA) in LRC were conducted1 ,4–8 with …

More challenges around sepsis: definitions and diagnosis

Sepsis is a complex and challenging syndrome, which can present in many ways and change quickly over time. Early recognition and timely management are key to help reduce its high associated morbidity and mortality (1). Zhang and colleagues recently published a guideline as part of The Society for Translational Medicine, entitled ‘clinical practice guidelines for diagnosis and early identification of sepsis in the hospital’ (2).

Perspectives and implications of the new sepsis clinical practice guidelines.

The Surviving Sepsis Campaign (SSC) advocates for early recognition and prompt treatment to decrease mortality from sepsis (1). Currently, the mortality rate associated with septic shock is greater than 40%, which makes early detection imperative (2-4). In the article by Zhang and colleagues entitled, “AME evidence series 001—The Society for Translational Medicine: clinical practice guidelines for diagnosis and early identification of sepsis in the hospital”, the authors discuss recent evidence that supports early recognition of sepsis (5). The comprehensive analysis examines the new definition of sepsis based on the guidelines published by the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) and provides a detailed assessment of sepsis screening using the Grades of Recommendation Assessment, Development and Evaluation (GRADE) framework.

Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Extranodal diffuse large B-cell lymphoma (DLBCL) and primary mediastinal B-cell lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Extranodal diffuse large B-cell lymphoma (DLBCL) and primary mediastinal B-cell lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Acute lymphoblastic leukaemia in adult patients: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Acute lymphoblastic leukaemia in adult patients: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Biliary cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Biliary cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Oesophageal cancer is the 19th most common cancer in the European Union (EU), with cca 45 900 new cases diagnosed in 2012 (1% of the total). In the EU, the highest age-standardised incidence rates for oesophageal cancer are in the Netherlands for men and the UK for women [1]. Variation between countries is high and may reflect different prevalence of risk factors, use of screening and diagnostic methods.

Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Diagnosis and clinical management of melanoma patients at higher risk of a new primary melanoma: A population-based study in New South Wales, Australia.

To describe the method of diagnosis, clinical management and adherence to clinical practice guidelines for melanoma patients at high risk of a subsequent primary melanoma, and compare this with melanoma patients at lower risk. The Melanoma Patterns of Care study was a population-based, observational study based on doctors' reported clinical management of melanoma patients in New South Wales, Australia, diagnosed with in situ or invasive melanoma over a 12-month period from October 2006. Of 2605 patients with localised melanoma, 1019 (39%) were defined as at higher risk due to the presence of one or more of the following factors: a family history of melanoma (11%), multiple primary melanomas (17%), or many naevi (24%). Compared to patients at lower risk, high risk patients were more likely to receive their initial care from a primary care physician (56% vs 50%, P = 0.002), have their melanoma detected during a routine skin check (40% vs 33%, P < 0.001), have their lesion assessed with dermoscopy (63% vs 56%, P = 0.002), and be encouraged to have skin surveillance (84% vs 77%, P < 0.001) and skin self-examination (87% vs 83%, P = 0.03). Higher socioeconomic status and urban residence were associated with patients at higher risk receiving initial treatment from a specialist doctor. Clinical management of higher risk patients was more likely to conform to clinical practice guidelines for diagnosis and skin surveillance than to melanoma patients at lower risk.

Clinical Practice Guidelines for Diagnosis and Management of Hypersensitivity Reactions to Contrast Media.

The objective of these guidelines is to ensure efficient and effective clinical practice. The panel of experts who produced this consensus document developed a research protocol based on a review of the literature. The prevalence of allergic reactions to iodinated contrast media (ICM) is estimated to be 1:170 000, that is, 0.05%-0.1% of patients undergoing radiologic studies with ICM (more than 75 million examinations per year worldwide). Hypersensitivity reactions can appear within the first hour after administration (immediate reactions) or from more than 1 hour to several days after administration (nonimmediate or delayed reactions). The risk factors for immediate reactions include poorly controlled bronchial asthma, concomitant medication (eg, angiotensin-converting enzyme inhibitors, ß-blockers, and proton-pump inhibitors), rapid administration of the ICM, mastocytosis, autoimmune diseases, and viral infections. The most common symptoms of immediate reactions are erythema and urticaria with or without angioedema, which appear in more than 70% of patients. Maculopapular rash is the most common skin feature of nonimmediate reactions (30%-90%). Skin and in vitro tests should be performed for diagnosis of both immediate and nonimmediate reactions. The ICM to be administered will therefore be chosen depending on the results of these tests, the ICM that induced the reaction (when known), the severity of the reaction, the availability of alternative ICM, and the information available on potential ICM cross-reactivity. Another type of contrast media, gadolinium derivatives, is used used for magnetic resonance imaging. Although rare, IgE-mediated reactions to gadolinium derivatives have been reported.

Comments to the project of Russian clinical practice guidelines for diagnosis and treatment of differentiated thyroid cancer.

The article is dedicated to the discussion about the project of Russian clinical practice guidelines for diagnosis and treatment of differentiated thyroid cancer.

Клинические рекомендации Российской ассоциации эндокринологов по диагностике и лечебно-профилактическим мероприятиям при врожденной дисфункции коры надпочечников у пациентов во взрослом возрасте

Клинические рекомендации Российской ассоциации эндокринологов по диагностике и лечебно-профилактическим мероприятиям при врожденной дисфункции коры надпочечников у пациентов во взрослом возрасте

Russian clinical practice guidelines for diagnosis and treatment of differentiated thyroid cancer

The project of Russian clinical practice guidelines for diagnosis and treatment of differentiated thyroid cancer is dedicated to the management of patients with differentiated thyroid cancer. The guideline modifications 2016 include the following matters: indication for fine-needle aspiration biopsy, calcitonin screening, standards for biopsy results, indication for suppressive therapy and thyroid replacement therapy, targeted therapy in patients with radioiodine-refractory differentiated thyroid cancer.

Russian Association of Endocrinologists clinical practice guidelines for diagnosis and treatment of pheochromocytoma and paraganglioma

Russian clinical practice guidelines are dedicated to the management of patients with pheochromocytoma and paraganglioma.