Leading doctors of city veterinary clinics claim that in recent years cases of infectious rhinotracheitis in cats have increased in association with infectious diseases of bacterial etiology, such as Escherichia coli, Shigella spp., Pasteurella haemolytica, Pasteurella multocida, Staphylococcus aureus, Staphylococcus hyicus, Streptococcus spp., Klebsiella spp., Proteus spp., Pseudomonas aeruginosa, Campylobacter spp., Mycoplasma spp., Haemophilus spp. The lack of unified and available methods of laboratory diagnosis of associated cat rhinotracheitis leads to a complicated course and difficulties in timely treatment of sick animals. The aim of the work was to determine the prevalence of respiratory diseases and diseases accompanied by damage to the lymphoid organs of cats in the city of Kryvyi Rih. The material for the work was the results of studies of purebred and outbred cats suffering from infectious diseases in the period from 2021 to 2022. Research was conducted in four private veterinary clinics in Kryvyi Rih, the results were systematized at the Department of Epizootology and Microbiology of the State Biotechnology University (Kharkiv). It was established that the share of infectious respiratory diseases was 19.3%, and the specific weight of infections with damage to lymphoid organs was 13.0%. It was found that infectious rhinotracheitis of cats was manifested in association with calicivirus, chlamydia, bordetelliosis, and mycoplasmosis. When studying the age dynamics of patients with associated infectious cat rhinotracheitis, it was established that the most frequently affected young animals were 10 weeks old (23.0%) and 12 weeks old (20.5%). In the list of immunodeficiencies in cats, such diseases as panleukopenia, viral immunodeficiency, infectious peritonitis, and viral leukemia were registered. In the study of sexual susceptibility to immunodeficiencies, it was established that a higher percentage — 61.5% — of females were ill than males — 38.5%