This study was carried out to determine some physical and mechanical properties of Uapaca kirkiana a lesser known timber species growing in public land near Iyondo Catchment Forest Reserve, Kilombero District, Morogoro, Tanzania. A total of 3 trees were used in the study. Preparation of test samples and laboratory procedure to determine some physical and mechanical properties followed standard methods. Analysis of variance was used to determine the variation between and within trees and regression analysis was used to determine relationship between wood basic density and mechanical properties. The results showed that Uapaca kirkiana has whitish sapwood and dark brown heartwood, with a mean basic density of 518.14 kg/m3. The properties of Uapaca kirkiana were as follows: modulus of elasticity (7185.69 N/mm2), modulus of rupture (59.7 N/mm2), work to maximum load (0.06 mmN/mm3), total work to failure (0.07 mmN/mm3), shear strength parallel to the grain (11.86 N/mm2), compression strength parallel to the grain (34.4 N/mm2) and cleavage strength (20.21 N/mm width). On axial direction, the modulus of elasticity, total work to failure, compression strength parallel to grain and cleavage strength were directly proportional to its basic density while modulus of rupture, work to maximum load and shear strength parallel to the grain were inversely proportional implying that Uapaca kirkiana is suitable for activities, which require high modulus of elasticity, total work to failure, compression strength parallel to the grain and cleavage strength. On radial direction modulus of elasticity, modulus of rupture, work to maximum load, compression parallel to the grain and cleavage strength were directly proportional to basic density while shear parallel to the grain was inversely proportional to basic density. Compared to Khaya anthotheca, the timber species found in the same location and market; it was found that the timber of Uapaca kirkiana had modulus of rupture and compression parallel to the grain far lower than those of Khaya anthotheca, while the work to maximum load, total work to failure, shear strength parallel to grain and modulus of elasticity were almost the same. Due to the similarity in some of their physical and mechanical properties, the wood of Uapaca kirkiana may berecommended to substitute Khaya anthotheca in wood works that require medium density wood like in decoration where colour is considered an important aspect for appearance and in cabinet, panel and furniture making though it is not adequate in high-class strength joinery. TJFNC Vol. 76 2007: pp. 94-101