Alkyl Cleavage Research Articles

DEMETHYLATION STUDIES. IV. THE IN VITRO AND IN VIVO CLEAVAGE OF ALKYL- AND ARYLALKYL-P-NITROPHENYL ETHERS.

DEMETHYLATION STUDIES. IV. THE IN VITRO AND IN VIVO CLEAVAGE OF ALKYL- AND ARYLALKYL-P-NITROPHENYL ETHERS.

Investigations on organo‐tin compounds. XIII

AbstractWhereas in α‐substituted organo‐tin nitriles and esters the functionally substituted group is easily removed from the tin atom, it appears that groups in which the substituent occupies a β‐position or beyond with respect to the tin atom are very resistant to tin‐carbon bond cleavage. With compounds containing groups of the latter type, the reactions studied result in rapid cleavage of unsubstituted aryl or alkyl groups.Various organo‐tin halides containing alkyl groups substituted in the β‐position or beyond are described.