You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Evaluation (II)1 Apr 20131390 INCREASED RISK OF DEVELOPING ERECTILE DYSFUNCTION SUCCESSIVELY WITH INCREASING AGE UP TO THE AGE OF 65 YEARS: DATA FROM A LONGITUDINAL STUDY IN MEN AGED 45 YEARS AND ABOVE Johan Stranne, Ulf Malmsten, Björn Areskoug, Ian Milsom, Ulla Molander, and Ralph Peeker Johan StranneJohan Stranne Gothenburg, Sweden More articles by this author , Ulf MalmstenUlf Malmsten Gothenburg, Sweden More articles by this author , Björn AreskougBjörn Areskoug Gothenburg, Sweden More articles by this author , Ian MilsomIan Milsom Gothenburg, Sweden More articles by this author , Ulla MolanderUlla Molander Gothenburg, Sweden More articles by this author , and Ralph PeekerRalph Peeker Gothenburg, Sweden More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.2744AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The aim was to explore the risk of developing erectile dysfunction (ED) over time in men aged 45 years and above followed longitudinally during a period of 11 years, adjusted for a number of known risk factors. METHODS A questionnaire containing questions relating to urogenital health issues such as urinary incontinence and erectile dysfunction was sent to a random sample (10 458) of men living in Gothenburg, Sweden in 1992. The men were from the age cohorts 45, 50, 55 years etc., up to the age of 85 or older. An analogous survey was sent to a random sample (10,845) of men from the age cohorts 46, 51, 56 years etc. resident in the city of Gothenburg in 2003. The response rate was 74.2% in 1992 (n = 7 763) and 67.8% in 2003 (n = 7 349). A total of 3256 men answered both questionnaires. We calculated the risk of developing ED for age cohort 45, 50, 55, 60, 65 and 70 years between the two questionnaires, 11 years apart, using variance analysis with repeated measures. The risk was adjusted for changes in known risk factors such as concomitant morbidity, intake of medication, smoking, alcohol consumption and physical exercise. RESULTS The prevalence of ED ranged from 1.1% in men aged 45 years of age to 10.4% in men aged 70 years at the baseline assessment in 1992 (Fig. 1). Between the two surveys the proportion of smokers in the population had decreased and the frequency of physical exercise had increased. This was paralleled by an increase in concomitant morbidity, intake of medications and in alcohol consumption, which was adjusted for in the analyses. There was a successive linear increase (+1.82% to +11.42%) in the prevalence of ED in the men grouped according to age at baseline from the age of 45 to a maximum at 65 years of age. CONCLUSIONS The risk of developing ED within 11 years increased successively from 45 to 65 years of age. The increase in risk was high already from the age of 50 years. For the older age cohorts in the study there is likely to have been a selection bias towards healthier, and potentially more potent men, answering both surveys. This information is important when planning and analyzing longitudinal interventional studies on ED in various age groups. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e569 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Johan Stranne Gothenburg, Sweden More articles by this author Ulf Malmsten Gothenburg, Sweden More articles by this author Björn Areskoug Gothenburg, Sweden More articles by this author Ian Milsom Gothenburg, Sweden More articles by this author Ulla Molander Gothenburg, Sweden More articles by this author Ralph Peeker Gothenburg, Sweden More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...