Circulation Problems Research Articles

Moisture‐Driven Actuators

AbstractWater constitutes a huge circulation network in solid, liquid and gaseous forms that contains inestimable recyclable energy. Obtaining energy from gaseous moisture is challenging but of great significance to promote the energy upgrading. The emergence of moisture‐driven actuator (MDA) provides an effective way in converting moisture energy to mechanical energy. The MDA can combine with water molecules through hygroscopicity and swell to produce macroscopic deformation. Due to the wide distribution of humidity and the wireless driving mode, MDA shows great application potential in the fields of environmental monitoring, remote control and energy harvesting. This paper comprehensively reviews the research progress of MDA from aspects of hydrophilic materials, structures, preparing methods, multi‐response integration and applications, aiming at providing guidance for the design, preparation and application of MDA. Besides, the challenges faced by MDA are analyzed and corresponding solutions are proposed, which points out the next stage developing direction of MDA.

The Problem of Internal Circulation of Foreign Coins in Russia in the 1830s

The monetary circulation of the Russian Empire in the 1st half of the 19th century went through several stages: from silver monometallism to the assignation monetary system and back to silver monometallism. The assignation monetary system, established in 1812, represented a unique phenomenon of world monetary circulation. The issue of internal circulation of foreign coins persisted throughout this period. Despite the prohibition of the internal circulation of foreign coins at the inception of the first silver monometallism in 1810, this regulatory decree was not consistently enforced, leading to the illicit circulation and accumulation of foreign coins. The 1830s emerged as a pivotal period during which the challenges associated with internal circulation significantly disrupted monetary turnover. Notwithstanding these obstacles, the financial management, led by Finance Minister E. F. Kankrin, demonstrated reluctance to implement drastic measures. The analysis concludes that the financial management under E. F. Kankrin did not perceive the circulation of foreign coins as a substantial threat to the Russian monetary system and exhibited hesitation in pursuing radical interventions, save for certain individuals aligned with Emperor Nicholas I.

Harmonic voltage compensation and harmonic current sharing strategy of grid-forming inverter

In a multi-inverter parallel system, the harmonic governance control strategy may worsen the system's current circulation problem due to the line impedance difference, which could further affect the stable operation of the system. To solve the problem, the strategy considering both power sharing and harmonic control is proposed in this paper. First, the microgrid system with background harmonics is modeled and analyzed. Based on the modeled system, a comprehensive control strategy for the grid inverter with harmonic voltage compensation and harmonic current sharing is established. In this paper, the output signal is controlled by frequency division. This paper adopts grid-forming control in the fundamental wave domain and employs harmonic voltage compensation control in the harmonic domain. The harmonic voltage is synthesized by collecting the specific harmonic current through the band-pass filter, compensating for the harmonic voltage drop on the line to improve the harmonic voltage quality of the point of common coupling(PCC). Aiming at the sharing problem caused by line impedance difference, virtual impedance control is introduced, harmonic impedance is redesigned according to the adjusted output impedance, and the harmonic output impedance before and after adjustment is measured and compared. The simulation results show that the proposed control strategy can not only reduce the harmonic content of the PCC voltage but also achieve the effect of equal harmonic current division.

An Experimental Study of the Retention Effect of Urban Drainage Systems in Response to Grate Inlet Clogging

The rainfall drainage characteristics of urban areas result in more surface runoff compared to soil surfaces. Conventional Urban Drainage Systems, CUDs, have disadvantages when managing this surface runoff, leading to urban water circulation issues such as flooding and depletion of groundwater. The performance of CUDs varies significantly depending on the clogging of grate inlets with various debris and shapes. To address these disadvantages, Sustainable Urban Drainage Systems, SUDs, have been proposed. This study compares the drainage efficiency of the two systems; using a physical model with an artificial rainfall simulator, an experimental study was conducted with respect to clogging type, clogging ratio, and rainfall intensity. Comparative analysis of peak flow rates and the peak time demonstrates the advantages of IRDs. As a result, IRDs are applicable to the mitigation of urban water circulation problems such as inundation.

Thrombotic antiphospholipid syndrome: Recurrent thromboses

Thrombotic antiphospholipid syndrome (APS) is a condition affecting young people in whom a thromboembolic event occurs in the presence of circulating antiphospholipid antibodies (aPL).The aim of this study was the evaluation of the incidence of recurrent thrombosis and its risk factors in antiphospholipid syndrome.Material and methods. The retrospective study included 98 patients with aPL who were followed up at the institute from 2014 to 2023, of whom 66 (67%) were women and 32 (33%) were men. Of the 98 patients with aPL, 48 (49%) had a diagnosis of systemic lupus erythematosus (SLE). Antiphospholipid antibodies (aPL), including antibodies to cardiolipin (IgG/IgM aCL), antibodies to ß2-glycoprotein 1 (IgG/IgM aß2GP1), antibodies to ß2-glycoprotein IgG against domain 1 (IgG aß2GP1-D1), antibodies to phosphatidylserine/prothrombin complex (IgG/ IgM aPS/PT) and other thrombotic risk factors. aPL was assessed by enzyme-linked immunosorbent assay (ELISA) and chemoluminescence assay (CHLA).Results. Thrombosis recurrence was reported in 62 (63%) of 98 patients, and 36 (35%) did not. The main cause of recurrent thrombosis was treatment with direct oral anticoagulants (DOACs). 24 (38.7%) of 62 patients with recurrent thrombosis were treated with DOACs, the duration of which ranged from 6 to 24 months. The next most common cause of recurrent thrombosis was the lack of continuous anticoagulant therapy in 20 (32.5%) of the patients. In 17 (27.4%) of the patients, the recurrence occurred while they were still taking warfarin. In 10 (41.7%) of the 24 patients, the recurrent thrombosis was arterial in origin. This was associated with recurrent cerebral circulation problems. The level of positivity did not matter, but all had triple IgG aPL positivity. 5 had lupus anticoagulant (LA) at the onset of the disease before anticoagulant use. IgG aPS/PT was most important in association with recurring thrombosis in the ELISA: 45 (72.6%) of 62 patients with recurring thrombosis were positive for IgG aPS/PT, compared with 19 (52.8%) of 36 patients without recurring thrombosis. The detection of all aPL was more frequent in CHMA than in ELISA. However, the definition of aPL in ELISA is recommended according to the latest classification criteria. Triple IgG positivity for aCL of IgG aß2GP1, IgG aß2GP1-D1 and CHMA remained a risk factor for recurrent thrombosis and increased the risk of recurrence more than threefold. Obesity was a risk factor for recurrent thrombosis, with a 5-fold increased risk of recurrent thrombosis in obese compared to non-obese patients (p=0.01).Conclusions. Recurrent thrombosis in APS is largely associated with IgG aCL, IgG aß2GP1, IgG aß2GP1-D1, IgG aPS/PT. Triple IgG aPL positivity in any combination significantly increased recurrent thrombosis risk.The presence of any type of aPL IgG in both ELISA and CHLA influenced the recurrence rate of thrombosis in APS.Obesity was a significant risk factor for recurrent thrombosis.

A question of autonomy: the Islamic-conservative cultural sphere in Turkey

ABSTRACT The Islamic-conservative cultural sphere in Turkey has rapidly expanded during the 20-year rule of Erdoğan’s Justice and Development Party. Despite popular debates regarding the rise of ‘conservative art’, academic studies have thus far limited their focus to the cultural policies and actions of the ruling power. Consequently, our understanding of cultural producers within this expanding sphere, their aesthetic viewpoints and their position within the broader cultural field remains limited. To address this gap, we employ Bourdieu’s field theory and explore the dynamics of this cultural sphere by conducting in-depth interviews with artists and cultural intermediaries active within Islamic/Islamist art circles. Our findings suggest that the sphere is relatively autonomous from the broader cultural field, characterized by its closed-circuit production and circulation network, specific forms of capital, and exclusive ties to the realm of power. However due to its own tensions and fragmentations, this autonomous sphere does not function as a monolithic bloc of Islamic/conservative forces struggling for legitimacy against an established secularist/Kemalist/leftist bloc, as has been often presumed throughout Turkish history. Our discussion also contributes to the broader Bourdieusian literature by questioning the utility of concepts such as ‘field’ and ‘pillars’ in comprehending contexts with emerging Islamic/conservative cultural sphere.

Mathematical Modelling of the Thermosolutal Effect on Blood Flow through a Micro-Channel in the Presence of a Magnetic Field

Substances such as mass concentrations in the blood cause circulation challenges. Blood is a substance made up of 55% plasma and 45% hemoglobin, which flows through the blood vessels and is aided by the heart in pumping to all organs and other tissues and cells in the human body. Mathematical modelling plays an important role in understanding the blood circulation problem in the human body, and it helps transform the real-life cardiovascular problem into a system of mathematical equations. In this research, we transformed the real-life cardiovascular problem of the heat effect on mass concentration and blood flow through blood vessels into a system of partial differential equations representing blood momentum, energy, and mass concentration equations after modifying the Navier-Stoke equation. The models are scaled from dimensional to dimensionless using specific scaling parameters. The scaled dimensionless equations were further perturbed and reduced to a system of ordinary differential equations, and the system of ODEs was solved using the Laplace method, where mathematical models representing blood velocity profiles, temperature profiles, and mass concentration profiles were obtained. A numerical simulation was performed using Wolfram Mathematica, version 12, where the effect of the pertinent parameters on the flow profiles was investigated and the results were presented graphically. The variation of the pertinent parameters such as the Grashof number, solutal Grashof number, Prandtl number, Soret number, Schmidt number, Darcy number, and magnetic field affect the flow profile such that the increase in Grashof number and solutal Grashof number causes the blood velocity to increase substantially at the centre of the vessel before decreasing to zero as the wall boundary layer increases, while the increase in Prandtl number and Soret number increases the blood temperature and velocity.

Generation and Analysis of a Dataset of Optimal Double-Loop Circulant Networks

Optimal circulant networks are of practical interest as graph models of reliable communication networks for supercomputer systems and networks on a chip. A large dataset of parameters of optimal double-loop circulant networks with a number of nodes of up to 50,000 and 451,000 points has been constructed. The dataset contains, for each number of vertices, all generators corresponding to optimal or suboptimal (in the absence of optimal) descriptions of the graph. This made it possible to find analytical dependencies of the parameters that define families of optimal graphs. Based on the analysis of the constructed dataset, the solution to the problem of determining optimal two-dimensional circulant networks is studied. A process is automated for determining analytical, parametric descriptions of the families of optimal double-loop networks, described polynomials of diameter. Having applied the methods of integrating differential evolution and reduced local search to the analysis of the generated dataset, we rediscovered a number of previously known families and found more than 200 new, different from all those known in literature, families of optimal double-loop networks with generators of linear and quadratic types of polynomials. Our new ap­proach can be applied to studing datasets of other promising classes of graphs and networks.

On farm conservation of cassava in traditional communities of Jangada, Mato Grosso State, Brazil: ethnobotany and genetic diversity

Jangada is a municipality in the Baixada Cuiabana region, State of Mato Grosso, Brazil. This study aimed to evaluate the collection of local cassava conserved by four traditional communities of Jangada in terms of ethnobotanical/socioeconomic and genetic aspects. Socioeconomic and ethnobotanical analyses were carried out with 40 farmers using qualitative techniques and descriptive statistics. Seven microsatellite markers were used for genetic analysis. A total of 182 cassava citations were verified, 31 of which were different. The Broto Branco variety was the most frequent (94.3%), followed by Vermelha Gaiadeira and Liberata (82.9 and 77.1%, respectively). The calculated median age for farmers was 56 years. Spearman’s coefficient indicated a positive correlation between the increase in farmer’s age and the number of cultivated local varieties. Few varieties are planted by many farmers, and most are planted by few farmers. High genetic diversity was observed, and most of the variability occurred within communities (88%). Two groups were formed in the cluster analysis, with two communities in each group. The propagule circulation network helped to understand the genetic similarity of communities with the closest geographic location. Cassava cultivation plays an important role in the studied communities, which maintain a high ethnobotanical and genetic diversity and relevant knowledge about the cultivated varieties.

Research progress and development of deep and ultra-deep drilling fluid technology

The research progress of deep and ultra-deep drilling fluid technology systematically reviewed, the key problems existing are analyzed, and the future development direction is proposed. In view of the high temperature, high pressure and high stress, fracture development, wellbore instability, drilling fluid lost circulation and other problems faced in the process of deep and ultra-deep complex oil and gas drilling, scholars have developed deep and ultra-deep high-temperature and high-salt resistant water-based drilling fluid technology, high-temperature resistant oil-based/synthetic drilling fluid technology, drilling fluid technology for reservoir protection and drilling fluid lost circulation control technology. However, there are still some key problems such as insufficient resistance to high temperature, high pressure and high stress, wellbore instability and serious lost circulation. Therefore, the development direction of deep and ultra-deep drilling fluid technology in the future is proposed: (1) The technology of high-temperature and high-salt resistant water-based drilling fluid should focus on improving high temperature stability, improving rheological properties, strengthening filtration control and improving compatibility with formation. (2) The technology of oil-based/synthetic drilling fluid resistant to high temperature should further study in the aspects of easily degradable environmental protection additives with low toxicity such as high temperature stabilizer, rheological regulator and related supporting technologies. (3) The drilling fluid technology for reservoir protection should be devoted to the development of new high-performance additives and materials, and further improve the real-time monitoring technology by introducing advanced sensor networks and artificial intelligence algorithms. (4) The lost circulation control of drilling fluid should pay more attention to the integration and application of intelligent technology, the research and application of high-performance plugging materials, the exploration of diversified plugging techniques and methods, and the improvement of environmental protection and production safety awareness.

Applications of the Fourier neural operator in a regional ocean modeling and prediction

In this paper, we apply the Fourier neural operator (FNO) paradigm to ocean circulation and prediction problems. We aim to show that the complicated non-linear dynamics of an ocean circulation can be captured by a flexible, efficient, and expressive structure of the FNO networks. The machine learning model (FNO3D and the recurrent FNO2D networks) trained by simulated data as well as real data takes spatiotemporal input and predicts future ocean states (sea surface current and sea surface height). For this, the double gyre ocean circulation model driven by stochastic wind stress is considered to represent an ideal ocean circulation. In order to generate the training and test data that exhibits rich spatiotemporal variability, the initial states are perturbed by Gaussian random fields. Experimental results confirm that the trained models yield satisfactory prediction accuracy for both types of FNO models in this case. Second, as the training set, we used the HYCOM reanalysis data in a regional ocean. FNO2D experiments demonstrated that the 5-day input to 5-day prediction yields the averaged root mean square errors (RMSEs) of 5.0 cm/s, 6.7 cm/s, 7.9 cm/s, 8.9 cm/s, and 9.4 cm/s in surface current, calculated consecutively for each day, in a regional ocean circulation of the East/Japan Sea. Similarly, the RMSEs for sea surface height were 2.3 cm, 3.5 cm, 4.2 cm, 4.6 cm, and 4.9 cm, for each day. We also trained the model with 15-day input and 10-day prediction, resulting in comparable performance. Extensive numerical tests show that, once learned, the resolution-free FNO model instantly forecasts the ocean states and can be used as an alternative fast solver in various inference algorithms.

Reconstructing the trade history: provenance study of Han bronze mirrors in and out of Han China

A rapidly increasing number of bronze mirrors dated to the Chinese Han dynasty (202 BC – AD 220), known for their unique decorative patterns and highly developed alloying techniques, have been widely discovered in both China and beyond, providing fresh materials and scientific data to revisit their geological provenance, production and circulation network along the ancient Silk Road. In this paper, 47 bronze mirrors unearthed in the southeastern provinces of China, including Zhejiang, Anhui and Fujian provinces, have been characterized by typo-chronology, lead isotopic analysis, compositional analysis and metallography. A much wider comparative study is also carried out through a combination of data from China, Japan, Central Asia, and Southeast Asia, leading to a more updated lead isotopic database of the Han mirrors spreading out of China in various directions. Compared with the traditional ‘optimal’ model based on the Han mirrors recovered in Japan, the current study contributes several key changes in the bronze mirror production of the Han dynasty. The systematic analysis of the alloy composition, trace elements and typological studies shows that the bronze mirror industry shifted towards a more standardized production in the middle to late Western Han Dynasty. In contrast to the substantial change of non-mirror bronze productions, the similar distribution of lead isotope data in early and middle to late Western Han mirrors suggests that the ‘official monopoly of salt and iron’ policy was less effective for the management of lead involved in mirror production. Bronze mirrors dated to middle to late Western Han discovered outside Han-China, such as Japan, Thailand, Afghanistan, Xiongnu and the ancient Dian Kingdom, appear to be subjected to a more specific type of lead as a result of the state-centralized policy of the Western Han court.

Virginia Woolf’s Common Readers in Paris

In this article, we analyze historical, biographical, geolocational, and book distribution data from the Shakespeare and Company Project to understand Virginia Woolf’s readership in Paris in the 1920s and 1930s. The lending library cards from Sylvia Beach’s archive reveal the names of Woolf’s readers, and include important information about their reading habits and professional lives. The article uses a mixed-methods approach, combining historical and archival research on individual readers with visualizations of demographic, literary, and geographical data. Datasets from the Shakespeare and Company Project provide unique access to the networks of distribution, circulation, and readership that defined Woolf’s literary presence in Paris. These networks, in turn, resonate with Woolf’s own deep interest in her various readerships and publics.

ТІНЬОВІ ВІДНОСИНИ ПРИ ВИРОБНИЦТВІ ТА ОБІГУ ПРОДУКЦІЇ РОСЛИННИЦТВА В УКРАЇНІ ТА НАПРЯМИ ЗАПОБІГАННЯ ЇМ

Introduction. The sector of national agricultural production and sales of plant products has significant volumes of the shadow economy. First of all, it is about shadow farming on the land and shadow circulation of plant products. Both the owners of the land, who manage non-publicly, and the economy of the country in general suffer from such negative phenomena. Moreover, shadow agrarian production affects other related industries, which increases the scope of the consequences of the illegal economy. Problem Statement. The problem of shadow production and circulation of plant products is complex and has existed for more than a decade. Attempts to solve this problem have not yielded real results so far. There are objective and subjective factors that have caused the existence of shadow production and circulation of plant products in Ukraine. After all, a situation has developed in the country, in which some business entities cannot manage land publicly for a number of objective reasons, while others benefit from shadow management. Participants in the shadow circulation of crop production are land owners who manage their own land alone or give land for use without registering the right to lease. The beneficiaries of the shadow circulation of crop production are land tenants, suppliers of commodity and material values for crop production, buyers of crop production and other subjects who seek and are able to receive profits from shadow operations. The purpose is to justify the necessity of detinization of land management processes and the circulation of plant products. Methods. The following methods are used: abstract-logical, systematization, dialectical and formal logic, expert evaluations. Results. Shadow farming on the land and shadow circulation of plant products were studied. A number of factors have been identified that cause the existence of shadow farming on land and the shadow circulation of plant products. The necessity and possibility of ending shadow farming on the land and the shadow circulation of plant products have been proven. Conclusions. The problems of shadow management on land and shadow circulation of plant products can be solved through legal, institutional and organizational mechanisms, the application of which will be aimed at creating conditions under which public management on land will provide the producer with more economic benefits than shadow management.

Simulation of Conducted Responses in Microvascular Networks: Role of Current Rectification by Endothelial Cell Gap Junctions

Neuronal activity in the brain stimulates local increases in blood flow. Such flow increases require dilation of feeding arterioles, which can be initiated by upstream conducted responses in the form of electrical currents transmitted along the endothelial lining of the vessels. One potential trigger for this response is hyperpolarization of capillary endothelial cells in active regions resulting from local elevation of extracellular K+ concentration. The conducted hyperpolarization causes arteriolar dilation. For this mechanism to be effective in delivering increased flow to a specific location, the conducted response must travel in the upstream direction only, without reentry into adjacent parallel flow pathways. Such specificity in the response to activation has been observed in skeletal muscle, and may result from partial rectification of current in gap junctions connecting adjacent endothelial cells. The goal of this work is to simulate the spread of hyperpolarizing currents along vessel walls in microvascular networks of the cerebral circulation, including the effects of rectification in gap junctions. A theoretical model was developed for the spread of electrical current in the endothelial cells of a network of microvessels in response to local K+- induced hyperpolarization. Transmembrane currents are represented in the model by a KIR-channel conductance, a non-voltage-dependent K+ conductance, and a background conductance. Currents along vessel walls are represented assuming asymmetric gap junction conductance between adjacent endothelial cells, with higher conductance for downstream currents (causing upstream hyperpolarization) than for upstream currents. The model was applied to a synthetic network of 45 segments, assuming 20 nS conductance for upstream propagation, while a range of values was used for downstream propagation. The model shows effective upstream propagation of conducted responses when the gap junction conductance for downstream propagation is 1 nS or less. This result was confirmed in a simulation of a reconstructed murine cerebral cortex network with 4881 segments. In conclusion, partial current rectification by endothelial gap junctions can result in preferential upstream propagation of conducted responses, consistent with experimental observations of local flow regulation. Supported by NIH grant U01 HL133362. This is the full abstract presented at the American Physiology Summit 2024 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.

Analysis Of The Effect Of Ergonomics and Circulation On The Comfort Of Dormitory Occupants: Around Maranatha Christian University

The dormitory is a temporary accommodation used by people who work or study. A place is needed for small activities and rest that can increase the spirit of the dormitory residents. Based on the available data, many dormitory rooms still have ergonomic and circulation problems, with the majority of the problems found being narrow circulation, to furniture that is too small such as tables. The purpose of this study is to examine the comfort of the rooms based on furniture ergonomics and layout. The data collection of this qualitative research was done by interviewing dormitory room residents around Maranatha Christian University. The results of this study are to determine the ergonomics, circulation of the dormitory room, and good perspectives so that it can increase the comfort of the residents to carry out activities in it, as well as find solutions and suggestions that can be taken to respond to problems found in the dormitory rooms studied around the Maranatha Christian University.

Drug utilization by the population as an indicator of health protection culture in the region

The relevance of the research is determined by the total dependence of the level of health of the population on the availability of medicines. The problem of consumer culture is among the problems of drug circulation, because the health of the nation directly depends on it. The state-economic program for providing the population with necessary products from the pharmaceutical industry is also related to the issues of health maintenance culture. The purpose of the research is to determine the population’s attitude towards the consumption of medicines as an indicator of health conservation. The study is based on the use of a questionnaire survey method. The main questions were the peculiarities of the respondents’ attitude towards taking medications, the question of medical prescription of drugs, the importance of drug prices for the population, the influence of advertising on drug consumption, etc. According to the survey results, it has been proven that the quality of life of the vast majority of people directly depends on the use of drugs. The culture of the population regarding the consumption of drugs is quite high, as evidenced by the information about studying theinstructions before taking the drug by the majority of respondents, a reasonable attitude towards advertising drugs in the media, and an optimal level of trust in the quality of pharmacy products. An important issue in the culture of health conservation remains the provision of people with chronic diseases with drugs for daily use, which should not be completely dependent on imports from other countries, as well as a pricing policy that allows patients to purchase the necessary medicine. Maintaining a high level of culture of drug consumption should be ensured by the state, which implements a reasonable social policy and effective control over meeting people's needs for resources to maintain the health of the nation.

Clinical challenges in asymptomatic chronic aortoiliac occlusive disease

Asymptomatic aortoiliac occlusive disease, while less common compared to other peripheral arterial diseases, presents unique clinical challenges. Our center recently encountered a case involving a patient with chronic occlusion of the distal abdominal aorta and bilateral iliac arteries. Remarkably, this patient had developed an extensive network of collateral circulation, effectively compensating for the reduced blood supply to the pelvic and lower limb areas. This adaptive physiological response resulted in the patient exhibiting no significant clinical symptoms. To reveal the most effective diagnostic and treatment strategies for asymptomatic peripheral artery disease patients to avoid complications and other challenges, more clinical studies are needed in the future.

Exploring the connection between diabetes duration, HbA1c levels, and peripheral neuropathy in type 2 diabetes patients

Diabetes mellitus can lead to blood circulation problems, which include both large-scale (macrovascular) and small-scale (microvascular) issues. One specific small-scale problem is the loss of feeling in the feet (known as peripheral neuropathy), which can cause foot ulcers and greatly increase the risk of needing an amputation. The length of time someone has had diabetes and their HbA1c levels (a measure of blood sugar control over time) are linked to the risk of developing diabetic peripheral neuropathy (DPN) in individuals with diabetes. The purpose of this study was to investigate the relationship between how long someone has had type 2 diabetes mellitus (T2DM) and their HbA1c levels with the presence of DPN. We conducted a correlational study with a cross-sectional design. We specifically chose 154 outpatients with T2DM from a hospital clinic for this study. To collect data, we used forms that included demographic information, the Michigan Neuropathy Screening Instrument (MNSI), and the Michigan Diabetic Neuropathy Score (MDNS). We analyzed the data using chi-square tests. Our findings showed a significant link between DPN and both the duration of diabetes and abnormal HbA1c levels in individuals with T2DM, with statistical significance (p=0.001) for both. We suggest that individuals with diabetes should manage their condition carefully to minimize the risk of complications from DPN. It is also recommended that hospitals regularly offer educational programs on neuropathy risks and prevention of severe complications to patients with T2DM.

Angelica Sinensis and Chinese Arborvitae: A Review on its Phytochemical & Pharmacological Importance

Angelica sinensis and Chinese arborvitae has had a long history of use in traditional Chinese medicinal herbs and have been used to heal various ailments such as heartburn, overnight urination, arthritis, circulation problems and androgenic alopecia, pain, hemorrhoids, abnormally heavy bleeding during menstrual periods and many other conditions. The modern pharmacological studies discovered that these two plants have a wide variety of beneficial attributes for human health. Besides, its importance, a review of this both plants have not been properly assessed in the scientific literature to date. Here, we review and summarize the historic and recent literature concerning the botany, phytochemistry, pharmacological activities, and toxicity of this wonder plant. This summary could be advantageous for future research objective to exploit the therapeutic potential of these beneficial medicinal plants.