The antenna plays an essential role in the medical industry. The short-range 5th Generation (5G) communication can be used for seamless transmission, reception, patient monitoring, sensing and measuring various processes at high speeds. A passive Ultra Wide Band (UWB) antenna, used as a sensor in the measurement of Prothrombin Time (PT) i.e., blood clot is being proposed. The investigated micro-strip patch UWB antenna operating in the frequency range of 3.1 to 10.6 GHz consists of a circular patch with a diamond-shaped slot made of jeans substrate material with good sensing properties is accomplished by adjusting the copper thickness of the patch. Due to the turbidity in blood plasma, PT measurement is the repetitive approach to get accurate value. In order to solve this issue, an antenna is designed, fabricated and analysed to obtain the accurate PT measurements from blood plasma. The blood clotting is observed by electromagnetic emitted voltage converted into the frequency range of 5 to 10 GHz and voltage range of 0.66 to 0.87 mV. The circular UWB antenna is constructed employing jean’s substrate with a partial ground plane to improve the S-parameter, gain, bandwidth and performance characteristics. The proposed antenna with Specific Absorption Rate (SAR) value within the acceptable range can be used as a wearable device in the human body, leveraging 5G technology. This antenna is well suited for various other applications like wireless sensors, wearable devices and short-range communication applications.