Circuit Components Research Articles

Full state observer-based pole placement controller for pulse width modulation switched mode voltage-controlled buck Converter

Switched mode DC-DC converters play an important role in today's renewable energy systems, electric Vehicles, consumer electrical appliances, and many more. While many researchers have designed controllers for DC-DC converters, achieving low implementation cost remains a significant hurdle. This paper proposes a cost-effective observer-based pole placement controller for a PWM voltage-controlled Buck converter with clear step by step design approach. The state space averaged model of the DC-DC power converter is used to design pole placement with integrator compensator and full state observer. Pole placement is employed to improve the transient and steady state behavior of Voltage reference tracking response and full state observer is applied to extract the inductor current with the aim of removing the actual current sensor. Design specifications are set to a settling time of less than 5 msec and an overshoot of less than 5 %. While designing Observer-Controller combination, the separation principle, designing the controller and observer independently, is utilized by placing the observer poles far to the left of the controller poles for the Observer to converge faster. The designed controller and observer is verified with simulation in MATLAB/SIMULINK software and design of developed controller and observer are realized using low-cost analog electronics circuit components The results shows that the proposed system's strength in tracking the reference output voltage even in the presence of input voltage disturbance and the mean value of inductor current is well extracted having only the output voltage and MOSFET gate signal.

Dynamic Multiplexed Control and Modeling of Optogenetic Systems Using the High-Throughput Optogenetic Platform, Lustro.

The ability to control cellular processes using optogenetics is inducer-limited, with most optogenetic systems responding to blue light. To address this limitation, we leverage an integrated framework combining Lustro, a powerful high-throughput optogenetics platform, and machine learning tools to enable multiplexed control over blue light-sensitive optogenetic systems. Specifically, we identify light induction conditions for sequential activation as well as preferential activation and switching between pairs of light-sensitive split transcription factors in the budding yeast, Saccharomyces cerevisiae. We use the high-throughput data generated from Lustro to build a Bayesian optimization framework that incorporates data-driven learning, uncertainty quantification, and experimental design to enable the prediction of system behavior and the identification of optimal conditions for multiplexed control. This work lays the foundation for designing more advanced synthetic biological circuits incorporating optogenetics, where multiple circuit components can be controlled using designer light induction programs, with broad implications for biotechnology and bioengineering.

Self-aligned, inkjet-printed resistors on flexible substrates with excellent mechanical stability, high yield, and low variance

Resistors are basic yet essential circuit components that must be fabricated with high precision at low cost if they are to be viable for flexible electronic applications. Inkjet printing is one of many additive fabrication techniques utilized to realize this goal. In this work, a process termed self-aligned capillarity-assisted lithography for electronics (SCALE) was used to fabricate inkjet-printed resistors on flexible substrates. Capillary channels and reservoirs imprinted onto flexible substrates enabled precise control of resistor geometry and straightforward alignment of materials. More than 300 devices were fabricated using poly(3,4-ethylene dioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) as the resistive material and silver as the electrode material. By varying PEDOT:PSS ink formulation and resistor geometry, resistances spanning from 170 Ω to 3.8 MΩ were achieved. Over 98% of devices were functional and the relative standard deviation in resistance ranged from 3% to 18% depending on resistor length and ink composition. The resistors showed no significant change in resistance after 10 000 cycles of bend testing at 1.6% surface tensile strain. In summary, this work demonstrated a fully roll-to-roll compatible process for inkjet printing resistors with superior properties.

Slip modes modeling of electric vehicle asynchronous electric drive

Purpose. Creation a computer model of electric drive of an electric vehicle with the possibility of modeling in slippage modes, as well as the subsequent determination of slippage detection method as early as possible to further reducing or preventing slippage. Methodology. Mathematical analysis and modeling. Findings. Mathematical models in the structural form of the control system, power converter and motor are added in a simplified way, as the blocks. For compiling a computer model, the blocks of the control system and the power converter will be assembled using models of elements of power electric circuits. The model allows the ED simulation with a huge number of parameters varying – modeling slipping processes with one or two wheels, a sharp change in engine parameters, failure of one of the components of the power circuit, etc. Using the Simulink and SimPower packages of the Matlab software package, as well as the block diagram of the electric drive, a computer model of the ED was synthesized. Computer simulation of dynamic processes in the electric drive during a collision, as well as pulling away on the road surface with a reduced coefficient of friction, was carried out. The obtained diagrams fully correspond to the real physical processes occurring in the electric vehicle and give reason to believe that the constructed mathematical and computer models are adequate. Proceeding from this, electromechanical transients in the electric drive during acceleration with slipping and one wheel runover a road surface with reduced traction were obtained and analyzed. As a result of this analysis, the most optimal and reliable way to determine the skidding mode for its further elimination was determined. Originality. Computer model of the asynchronous electric drive of an electric vehicle with a detailed mechanical part, taking into account the mechanical differential gear, was built. The model allows the ED simulation with a huge number of parameters varying – modeling slipping processes with one or two wheels, a sharp change in engine parameters, failure of one of the components of the power circuit, etc. Practical value. Computer simulation was carried out for two modes: start of electric vehicle movement , when one of the wheels has been of on the road surface with a reduced coefficient of adhesion (0,1) since launch and acceleration with a collision with a surface with a reduced coefficient of adhesion (0,1) with one wheel at the moment of time of 6.3 s.

Learning Circuits and Coding with Arduino Board in Higher Education Using Tangible and Graphical User Interfaces

The integration of the Arduino board into educational settings has penetrated across various educational levels. The teaching of this subject can be accomplished by (a) using real components in breadboards, (b) prefabricated modular boards that snap together, and (c) utilizing computer simulations. Yet, it is unknown which interface offers a more effective learning experience. Therefore, this experimental study aims to compare the effectiveness of these interfaces in a series of three laboratory exercises involving 110 university students, who were divided into three groups: (a) the first group used a tangible user interface, implementing circuits on breadboards, (b) the second group also used a tangible interface but with modular boards, and (c) the third group used a graphical user interface to simulate circuits using Tinkercad. For each laboratory exercise, students completed both pretests and posttests. Also, they provided feedback through five Likert-type attitude questions regarding their experiences. In terms of data analysis, t-tests, ANOVA, and ANCOVA, along with bootstrapping, and principal component analysis were employed. The results suggest that among the participants, those who used a graphical user interface stated that their understanding of the interconnection of components in microcontroller circuits was enhanced, while students with previous experience in microcontroller labs found the circuit creation process easier than students without experience.

Spallation and particles infusion into the extracorporeal circuit during CRRT: a preventable phenomenon

Patients in intensive care are exposed to the risk of microparticle infusion via extracorporeal lines and the resulting complications. A possible source of microparticle release could be the extracorporeal circuit used in blood purification techniques, such as continuous renal replacement therapy (CRRT). Disposable components of CRRT circuits, such as replacement bags and circuit tubing, might release microparticles such as salt crystals produced by precipitation in replacement bags and plastic microparticles produced by spallation. In-line filtration has proven effective in retaining microparticles both in in-vitro and in-vivo studies. In our study, we performed an in-vitro model of CRRT-treatment with the aim of detecting the microparticles produced and released into the circuit by means of a qualitative and quantitative analysis, after sampling the replacement and patient lines straddling a series of in-line filters. Working pressures and flows were monitored during the experiment. This study showed that microparticles are indeed produced and released into the CRRT circuit. The inclusion of in-line filters in the replacement lines allows to reduce the burden of microparticles infused into the bloodstream during extracorporeal treatments, reducing the concentration of microparticles from 14 mg/mL pre in-line filter to 11 mg/mL post in-line filter. Particle infusion and related damage must be counted among the pathophysiological mechanisms supporting iatrogenic damage due to artificial cross-talk between organs during CRRT applied to critically ill patients. This damage can be reduced by using in-line filters in the extracorporeal circuit.

Network-level encoding of local neurotransmitters in cortical astrocytes

Astrocytes, the most abundant non-neuronal cell type in the mammalian brain, are crucial circuit components that respond to and modulate neuronal activity through calcium (Ca2+) signalling1–7. Astrocyte Ca2+ activity is highly heterogeneous and occurs across multiple spatiotemporal scales—from fast, subcellular activity3,4 to slow, synchronized activity across connected astrocyte networks8–10—to influence many processes5,7,11. However, the inputs that drive astrocyte network dynamics remain unclear. Here we used ex vivo and in vivo two-photon astrocyte imaging while mimicking neuronal neurotransmitter inputs at multiple spatiotemporal scales. We find that brief, subcellular inputs of GABA and glutamate lead to widespread, long-lasting astrocyte Ca2+ responses beyond an individual stimulated cell. Further, we find that a key subset of Ca2+ activity—propagative activity—differentiates astrocyte network responses to these two main neurotransmitters, and may influence responses to future inputs. Together, our results demonstrate that local, transient neurotransmitter inputs are encoded by broad cortical astrocyte networks over a minutes-long time course, contributing to accumulating evidence that substantial astrocyte–neuron communication occurs across slow, network-level spatiotemporal scales12–14. These findings will enable future studies to investigate the link between specific astrocyte Ca2+ activity and specific functional outputs, which could build a consistent framework for astrocytic modulation of neuronal activity.

Bundle branch reentrant ventricular tachycardia in a patient with Fabry disease

BackgroundBundle branch reentrant ventricular tachycardia is a unique type of VT that employs both bundles and the ventricular septum as integral components of a re-entrant circuit. It is usually observed in dilated cardiomyopathy, and its circuit depends exclusively on the specialized conduction system.Case presentationA 67-year-old man with a history of Fabry disease, and atrial fibrillation ablation, was admitted for a wide QRS tachycardia at 150 bpm, with an LBBB. Pharmacological therapy failed to stop the arrhythmia. Intracardiac recordings confirm the diagnosis. His Bundle recordings are essential, and Atrioventricular (AV) dissociation is typically present. The method used to induce left BBRVT is right ventricle apex stimulation. An electrophysiological study showed an AV dissociation a long HV sequence and a similar QRS morphology between VT and sinus rhythm. An overdrive stopped it. The same arrhythmia reappears and is restored to sinus rhythm by electrical cardioversion. We decided to implant an Implantable Cardiac defibrillator (ICD) with a backup pacing for secondary prevention and to ablate the right bundle branch.ConclusionBBRVT is a rare entity that is underreported. Pharmacological therapy is usually inefficient. An ICD is recommended for secondary prevention and can provide backup pacing, frequently required after catheter ablation to prevent the development of AV block or an excessive prolonged HV interval. Catheter ablation of the bundle branch is the first-line therapy.

Liftoff of a soft-actuated micro-aerial-robot powered by triboelectric nanogenerators

Aerial insects can nimbly navigate in cluttered natural environments while they interact with delicate objects such as flowers and leaves. To achieve insect-like agility and robustness, power dense dielectric elastomer actuators (DEAs) have been developed for driving sub-gram micro-aerial-vehicles (MAVs). However, despite exhibiting muscle-like bandwidth and resilience, DEAs require a high driving voltage in the range of 1 – 2 kilovolts. This requirement poses substantial challenges for developing compact boost electronics and energy sources, which prohibit power autonomous operations of soft-actuated sub-gram MAVs. Here, we develop a compact and high power triboelectric nanogenerator (TENG) that can effectively charge a high-voltage DEA and enable the liftoff of a soft-actuated MAV. We propose an In-plane Charge Pump (ICP) design that can deliver over 1500 V and 110 mW without requiring a secondary charge pump or magnetic circuit components such as inductors or transformers. Compared to conventional free-standing mode TENGs, our ICP design shows a 280 % and 920 % increase in voltage and energy generation, respectively. When this TENG powers a DEA-driven MAV, the 160 mg robot achieves liftoff with a lift-to-weight ratio of 1.75. This result highlights the potential of powering high-voltage microrobots with energy-harvesting devices.

Scaling up of a Self-Confined Catalytic Hybridization Circuit for Robust microRNA Imaging.

The precise regulation of cellular behaviors within a confined, crowded intracellular environment is highly amenable in diagnostics and therapeutics. While synthetic circuitry system through a concatenated chemical reaction network has rarely been reported to mimic dynamic self-assembly system. Herein, a catalytic self-defined circuit (CSC) for the hierarchically concatenated assembly of DNA domino nanostructures is engineered. By incorporating pre-sealed symmetrical fragments into the preying hairpin reactants, the CSC system allows the hierarchical DNA self-assembly via a microRNA (miRNA)-powered self-sorting catalytic hybridization reaction. With minimal strand complexity, this self-sustainable CSC system streamlined the circuit component and achieved localization-intensified cascaded signal amplification. Profiting from the self-adaptively concatenated hybridization reaction, a reliable and robust method has been achieved for discriminating carcinoma tissues from the corresponding para-carcinoma tissues. The CSC-sustained self-assembly strategy provides a comprehensive and smart toolbox for organizing various hierarchical DNA nanostructures, which may facilitate more insights for clinical diagnosis and therapeutic assessment.

Assessing the efficiency of measures to enhance electric power quality in variable-frequency drive for scraper conveyors

The intensive implementation of variable-frequency drive machines and installations in underground mining processes necessitates addressing several issues, with a primary focus on ensuring the quality of electric power. Elevating the energy resource of mining machines and enhancing the energy efficiency of mining operations requires maintaining the rated indicators of electric power quality in mine power distribution systems. Achieving this involves assessing the level and composition of higher harmonic components in voltage and current within power circuits equipped with variable-frequency drives (VFD). Key objectives encompass the development of a simulation model based on the equivalent diagram of the power distribution system substitution with a scraper conveyor VFD to scrutinize the spectral composition of higher harmonic components in the power circuits of the mine power distribution system (MPDS). Additionally, the study involves analyzing the impact of harmonic filters (HFs), reactors, and sine filters on the quality of electric power in the VFD system of a scraper conveyor. Further analysis extends to the spectral composition of higher harmonic components in circuits related to insulation leakage and metering circuits of the residual-current device. Practical recommendations for improving electric power quality in the VFD system of a scraper conveyor are then developed based on the research findings. The established model of a variable-frequency drive system for scraper conveyors facilitates the assessment of the effectiveness of electric power quality improvement measures. The harmonic composition of voltage and current in the mine power distribution system is determined under maximum distortion conditions and in the presence of HFs, reactors, and sine filters. Research methods are chosen to unveil the spectral composition of voltage and current in symmetrical and single-phase modes of insulation leakage, as well as in metering circuits of residual-current devices (RCDs). It is noted that the harmonic composition of leakage voltage and current is primarily influenced by the parameters of the output voltage modulated by the autonomous frequency converter inverter. Considering the high level of harmonic components in voltage and current, adjustments to RCD settings, capacitive current compensator, and the protective shunting unit are recommended for electrical safety. The study emphasizes the importance of scientifically substantiating the rated indicators of higher harmonic components for leakage circuits and further exploring the physiological effects of higher current harmonics on the human body. The feasibility of installing a harmonic filter (HF) directly on the low-voltage supply section of a scraper conveyor should be technically justified. Interestingly, the presence of HFs, reactors, and sine filters does not significantly impact the harmonic composition or the magnitudes of coefficients of the harmonic components in the phase voltage of the system concerning ground and leakage currents through insulation. However, higher harmonic components induced in leakage current circuits may pose a potential hazard, leading to a violation of magnetic compatibility and posing risks in case of contact with live parts of electrical equipment.

Effect of PCM-filled hallow fin heat sink for cooling of electronic components — a numerical approach for thermal management perspective

This paper aims at the PCM-based heat sink for electronic cooling. In the present analysis, paraffin wax-based phase change material (PCM), in 3-fin and 4-fin hollow heat sinks with the proper volume of PCM in the temperature of the electronic components can be controlled. The PCM-filled heat sinks are placed on top of the high heat-generating integrated circuit (IC) components. The aim is to reduce the maximum temperature of the electronic components and keep them below their critical temperature, hence increasing the life of the IC chips. A correlation is put forward for dimensionless temperature ([Formula: see text]) in terms of heat flux ([Formula: see text]), volume content ([Formula: see text]) and size of the IC chips ([Formula: see text]). It has been found that there will be a 4–[Formula: see text]C drop in temperature when compared to solid fins heat sinks. It is confirmed that the temperature of the IC chip is a strong function of heat flux, size and volume content of PCM.

Design of Impedance Matching Network for Low-Power, Ultra-Wideband Applications

This paper addresses the design of ultra-wideband (UWB) impedance matching networks operating in the unlicensed 3.1–10.6 GHz frequency band for low-power applications. It improves the simplified real frequency technique (SRFT) by adding a realizability check and employing an iterative approach with different initial guesses in optimization to achieve realizable solutions under the requirements of UWB, low-power consumption, and a minimum number of circuit components. The comparison of solutions obtained using the SRFT with published solutions based on the Chebyshev filter theory is presented. It is shown that the optimal SRFT solution requires fewer components in the impedance matching network, maximizes the RF power delivery over the UWB spectrum with a reflection coefficient below −10 dB, and allows for circuit optimization to reduce power consumption. Using the improved SRFT, it demonstrates a systematic approach to find the strategies and limitations of designing the input matching networks for low-power UWB applications using GlobalFoundries 90 nm BiCMOS technology.

Reducing hydrophobic drug adsorption in an in-vitro extracorporeal membrane oxygenation model

Extracorporeal membrane oxygenation (ECMO) is a life-saving cardiopulmonary bypass technology for critically ill patients with heart and lung failure. Patients treated with ECMO receive a range of drugs that are used to treat underlying diseases and critical illnesses. However, the dosing guidelines for these drugs used in ECMO patients are unclear. Mortality rate for patients on ECMO exceeds 40% partly due to inaccurate dosing information, caused in part by the adsorption of drugs in the ECMO circuit and its components. These drugs range in hydrophobicity, electrostatic interactions, and pharmacokinetics. Propofol is commonly administered to ECMO patients and is known to have high adsorption rates to the circuit components due to its hydrophobicity. To reduce adsorption onto the circuit components, we used micellar block copolymers (Poloxamer 188TM and Poloxamer 407TM) and liposomes tethered with poly(ethylene glycol) to encapsulate propofol, provide a hydrophilic shell and prevent its adsorption. Size, polydispersity index (PDI), and zeta potential of the delivery systems were characterized by dynamic light scattering, and encapsulation efficiency was characterized using High Performance Liquid Chromatography (HPLC). All delivery systems used demonstrated colloidal stability at physiological conditions for seven days, cytocompatibility with a human leukemia monocytic cell line, i.e., THP-1 cells, and did not activate the complement pathway in human plasma. We demonstrated a significant reduction in adsorption of propofol in an in-vitro ECMO model upon encapsulation in micelles and liposomes. These results show promise in reducing the adsorption of hydrophobic drugs to the ECMO circuits by encapsulation in nanoscale structures tethered with hydrophilic polymers on the surface.

Assembly mechanisms of the neuronal gap junction channel connexin 36 elucidated by Cryo-EM

Electrical synapses are essential components of neural circuits. Neuronal signal transduction across electrical synapses is primarily mediated by gap junction channels composed of Connexin36 (Cx36), the lack of which causes impaired electrical coupling between certain neurons including cortical interneurons and thalamic reticular nucleus (TRN) neurons. However, the structural basis underlying Cx36 function and assembly remains elusive. Recently, Lee et al. reported cryo-EM structures of Cx36, thus provided first insights of its gating mechanism. Here, we report a consistent cryo-EM structure of Cx36 determined in parallel, and describe unique interactions underpinning its assembly mechanism in complementary to the competing work. In particular, we found non-canonical electrostatic interactions between protomers from opposing hemichannels and a steric complementary site between adjacent protomers within a hemichannel, which together provide a structural explanation for the assembly specificity in homomeric and heteromeric gap junction channels.

Microbiologically influenced corrosion can cause a dental implant rejection

In the present study, we apply electrochemical and molecular biology approaches to establish whether microbiologically influenced corrosion (MIC) may be the reason for dental implant rejection. Titanium-based implants have been incubated in vitro in Ringer/glucose solution in the presence and absence of a salivary microbiota and the change in their corrosion potential and current density was monitored over time by potentiodynamic polarization. The charge transfers processes occurring on the Ti-based implant surface during the initial bacterial adhesion and after biofilm formation were analyzed by electrochemical impedance spectroscopy. The components of the equivalent electrical circuit as well as the heterogeneous electron transfer rate constants were estimated. In parallel, bacterial species from the salivary microbiota have been identified by sequencing of the 16S ribosomal amplicon method, and their contribution to the corrosion processes of dental implants was verified and compared to that of native saliva in vitro. The scanning electron microscopy observation and energy dispersive spectroscopy analysis of the implant surface after long-term exposure to a bacterial-containing environment revealed more detailed features of the occurring corrosion processes.

Molecular Structure Effects on Ionic Diode Performance in Desalination: Ultrahigh Rectification in Butylated Intrinsically Microporous Polyamine (PIM‐EA‐TB)

AbstractIonic diodes are components in ionic circuits for AC‐electricity driven desalination and ion extraction processes. Independent of the ionic diode type/mechanism, achieving ionic current rectification at high ionic strengths is challenging but important, for example in seawater desalination and treatment of brine. Here, the butylation of a molecularly rigid (glassy) polymer of intrinsic microporosity (PIM‐EA‐TB) is shown to give anionic diodes with ultrahigh rectification effects (associated with interfacial resistivity) even in high ionic strength aqueous 2 M NaCl solution. The effect is rationalised based on polymer structure affecting ion transport.

Electric circuit representation of the human circulatory system to estimate the position of nanosensors in vessels

Nanodevices are the focus of research enhancing the detection and treatment of diseases in the human body. Focusing on the scenario where nanosensors are flowing with the blood in the human circulatory system (HCS), in this work, we investigate a model to predict their distribution along the various vessel segments. Although various approaches report solutions for localizing nanosensors in the body, it is also relevant to derive their stationary distribution along the vessel segments as a prior step to assess their actuation and sensing capabilities in the body. We use a Markov chain formulation to derive the stationary distribution of nanosensors. We evaluate the transition probabilities relying on the representation of vessels with electric circuit components. We implement the electric circuit representation of the left ventricle in the heart and the arteries to find the blood flow at vessel bifurcations and then compute the Markov chain probabilities. Our system also allows to reveal the dynamics of the movement of nanosensors with the human activity. We illustrate results in two regimes, as low and high activity, to mimic the case when being at rest or doing sports.

Frequency reconfigurable circular microstrip G-slotted antenna with DGS for various wireless applications

Frequency reconfigurable circular microstrip G-slotted antenna with DGS for various wireless applications

Value-related learning in the olfactory bulb occurs through pathway-dependent perisomatic inhibition of mitral cells.

Associating values to environmental cues is a critical aspect of learning from experiences, allowing animals to predict and maximise future rewards. Value-related signals in the brain were once considered a property of higher sensory regions, but their wide distribution across many brain regions is increasingly recognised. Here, we investigate how reward-related signals begin to be incorporated, mechanistically, at the earliest stage of olfactory processing, namely, in the olfactory bulb. In head-fixed mice performing Go/No-Go discrimination of closely related olfactory mixtures, rewarded odours evoke widespread inhibition in one class of output neurons, that is, in mitral cells but not tufted cells. The temporal characteristics of this reward-related inhibition suggest it is odour-driven, but it is also context-dependent since it is absent during pseudo-conditioning and pharmacological silencing of the piriform cortex. Further, the reward-related modulation is present in the somata but not in the apical dendritic tuft of mitral cells, suggesting an involvement of circuit components located deep in the olfactory bulb. Depth-resolved imaging from granule cell dendritic gemmules suggests that granule cells that target mitral cells receive a reward-related extrinsic drive. Thus, our study supports the notion that value-related modulation of olfactory signals is a characteristic of olfactory processing in the primary olfactory area and narrows down the possible underlying mechanisms to deeper circuit components that contact mitral cells perisomatically.