A 37-year-old white woman was first examined by an ophthalmologist in December, 1960, for a pig mented lesion of the sclera (Fig. 1) which had re mained unchanged for the preceding 10 years. The scleral lesion was grey, 4 mm in diameter, and lo cated 5 mm posterior to the superior limbus in the vertical meridian. The lesion was neither elevated nor vascularized. On gonioscopic examination, a tu mor mass was detected in the angle in a position corresponding to the location of the scleral lesion (Fig. 2). The ciliary body was unremarkable, and the visual acuity and intraocular pressure were nor mal. The pupil was of normal size and shape and dilated normally. Examination in 1961 demonstrated no change in the findings. In 1962, the scleral lesion was slightly elevated and had increased to a diame ter of 10 mm. At this time, a smooth, slightly ele vated ciliary body tumor was noted which corre sponded to the site of the scleral lesion. There was no further change until 1969, when progressive growth of the ciliary body and angle tumor became obvious (Figs. 3 and 4). The extrascleral extension at this time measured 5 mm in diameter. The appar ent decrease in size since 1962 was attributed to loss of pigment. The patient was referred to the Uni versity of California, San Francisco, for consulta tion and the eye was enucleated on October 23, 1969.