Chronic Recurrent Cystitis Research Articles

The Association between Chronic Inflammation and Recurrent Cystitis in Women

The Association between Chronic Inflammation and Recurrent Cystitis in Women

The modern approach to intravesical therapy of chronic cystitis

The difficult of treating patients with chronic recurrent cystitis are caused by various factors like virulence of uropathogenic Escherichia coli, and the state of the local resistance of the bladder mucosa and their interaction. Instilan instillations in the treatment of patients with chronic cystitis led to a pronounced positive dynamics of clini cal 95% of patients, as well as to reduce the number of recurrences of cystitis more than 2 times, which greatly improved the quality of life of patients. The results allow us to recommend the use of intravesical sodium hyaluronate for the treatment of various forms of chronic cystitis.

The usage of intravesical laser therapy in chronic cystitis combined treatment

The purpose of the research. Evaluating the effectiveness of intravesical laser therapy in the treatment of chronic cystitis. Patient and methods. 76 women with chronic recurrent cystitis were appointed standard antibacterial together with intravesical laser therapy (10 sessions). The parameters of the laser radiation were selected individually depending on the severity of pain syndrome.The duration of laser irradiationwas from 3 to 5 minutes. Results. Urinary frequency and intensity of pain syndrome decreased in 1.8 times and 2.2 times to 3-month and in 2 and 2.4 times to 6 month after the end of treatment, respectively. During the observation the relapses of chronic cystitis developed only at 3 (3,9%) of 76 treated patients. Conclusion. The research results showed the possibility and expediency of inclusion of intravesical laser therapy in complex treatment of patients with chronic recurrent cystitis.

Treatment of Chronic Cystitis in Children

Chronic inflammatory processes of the urinary bladder’s wall dominate in the structure of urologic diseases in children, but the issue of their treatment still remains very acute. Despite the use of modern methods of treatment, children with chronic recurrent cystitis constitute a significant part of the total number of hospitalized patients (19 to 21%). In recent years quite many morphological studies of the bladder’s mucosa during inflammatory diseases were held. However, the mechanism that leads to the damage of the urothelium in chronic cystitis and factor that determines the type of metaplasia during inflammation of the bladder are unclear. Endoscopic examination, in some cases, does not allow differentiating inflammatory from tumor-like lesions of the mucosa. Destructive lesions of the bladder’s mucosa occur during exacerbation of chronic inflammation or severe, far gone acute inflammation. Therefore, conducting endovesical biopsy is necessary for clarifying forms of chronic cystitis and identifying urothelial hyperplasia or dysplasia and is critical in the diagnosis of diseases of the urinary bladder. It is still unclear under what endoscopic and morphological forms of recurrent cystitis in children neurogenic bladder disorders are more frequent and for what form of recurrent cystitis most pronounced neurogenic bladder dysfunctions are more likely to occur. The nature and extent of neurogenic disorders in children with various forms of recurrent cystitis in the late periods after antireflux surgeries remain unexplored.

Assessment of microcirculation’s condition of the bladder wall at women with chronic recurrent cystitis

The aim of study was studying of microcirculation’s condition in the bladder wall at patients with chronic recurrent cystitis. Patient and methods. For the investigation of the bladder wall microcirculation the original technique of intravesical high-frequency ultrasonic dopplerography (USDG) with help of which the study of the bladder wall blood-flow at 37 women with chronic recurrent cystitis was carried out as well as at 32 healthy women from the control group. Results. The method of USDG gave the possibility to estimate the blood-flow condition in the bladder wall at women with chronic cystitis and to establish the existence and extent of its violations. Conclusion. The disorder of the microcirculation can be considered as one of the major factors promoting a chronization and recurrency of the inflammatory process in the bladder wall. The prescription of medications improving the blood-flow in the bladder wall is pathogenetic defensible

Community Transmission in the United States of a CTX-M-15-Producing Sequence Type ST131 Escherichia coli Strain Resulting in Death

A middle-aged woman developed fatal urosepsis due to a multidrug-resistant Escherichia coli strain representing sequence type ST131, a recently emerged, disseminated, multidrug-resistant extraintestinal pathogen, after presumably having acquired it from her extensively antibiotic-exposed sister with chronic recurrent cystitis. Susceptibility results (reported on day 4) showed resistance to the initially selected regimen.

Psychosomatische Aspekte der chronisch rezidivierenden Zystitis

In spite of intensive research, chronic recurrent cystitis is etiologically a still insufficiently understood clinical picture. A 52-year-old patient presented with recurrent cystitis that had been treated exclusively somatically for years for which at least a psychosomatic co-pathogenesis of magnitude of the discomfort was diagnostically representable as well as being of therapeutic utility. In recollection of a bio-psychosocial understanding of human diseases, psychosomatic considerations should be undertaken at last but not least in patients with persistent cystitis.

Hémorragie sous-arachnoïdienne anévrismale et maladie de Wegener : une association peu commune

Background Wegener granulomatosis (WG) is an uncommon systemic necrotizing vasculitis that demonstrates renal and respiratory tropism. While the pathogenesis of WG remains controversial, autoimmune and inflammatory mechanisms are likely to be involved. The nervous system could be affected in up to 54% of cases. Although central nervous system involvement has been reported in 7–11% of cases, aneurysmal subarachnoid hemorrhage (SAH) occurrence is exceptional. Methods We describe the third reported case of WG-related aneurysmal SAH and then discuss the diagnosis and pathogenesis of WG along with the physiopathology of intracranial aneurysm in light of recent data reported in the literature. Results A 63-year-old woman with WG was referred to our neurosurgical department for aneurysmal SAH. The vasculitis diagnosis had been established 4 years earlier when she presented with chronic sinusitis, recurrent cystitis, and renal failure. The cerebral angiography revealed an anterior communicating artery dysplastic aneurysm. The neurosurgical management of the aneurysm was scheduled but delayed because the patient was experiencing a vasculitis flare-up. Immunosuppressive therapy and intravenous corticotherapy were given, with the patient's improvement, allowing neurosurgical clipping of the aneurysm. Conclusions Wegener granulomatosis-related aneurysmal SAH is an exceptional condition in neurovascular pathology. As inflammatory mechanisms are involved in the pathogenesis of aneurysm, the vasculitis flare-up could account for this SAH. The management of WG could benefit from anti-inflammatory therapy, as could the vasculitis-related SAH. SAH occurrence in patients with systemic vasculitis could indicate a vasculitis flare-up.