Objective: Diabetes is one of the most common chronic diseases in older adults in China, accompanied with higher demanding on caregiver. But the impact of caregiver on old diabetic inpatient in one-year readmission still unknown. Method: This longitudinal study was conducted at the Center of Gerontology and Geriatrics, West China Hospital from December 2011 to October 2012. All participants were followed up until December 2013. Demographics of diabetic inpatients (60 years and older) and ADLs, IADLs, timed “Up and Go” test (TUG), frailty were assessed, their caregiver were assessed by the Chinese version of the validated Zarit Burden Interview. The demand of caregiver was defined as following: more than two dependence of ADL and/or IADL and TUG more than 30s.The number of one-year readmission were collected by HIS or phone. Results: A total of 145 diabetic inpatients were enrolled. Patients with caregiver were 67(46.21%), only 37(55.23%) of them targeted the standard of caregiver demand. Average age of all caregivers were 59.39 ± 14.35 (range 24 to 90), 52(78.8%) of them were female, 54.5% were patients’ spouses. Half of patients 39(58.21%) with caregiver readmitted to hospital less than 1 time in a year. After adjusting by age, gender, Marital status, level of education, evaluation of caregiver’s current health status (OR 0.391), occupation besides caregiver, caregiver’s attitude (OR 3.259) and their mood to their patients (OR 2.071) were the risk factors for one-year readmission. Conclusion: For diabetic inpatients in China, the standard of caregiver demanding criteria need to set up. Caregiver’s psychological problems should be paid more attention.