Event Abstract Back to Event Two-way active avoidance memory consolidation in rats with scopolamine infusions in basolateral amygdala and ventral hippocampus Pere Boadas-Vaello1*, Anna Carballo-Marquez1, Irene Villarejo-Rodríguez1, Anna Vale-Martinez1, Gemma Guillazo-Blanch1 and Margarita Marti-Nicolovius1 1 Universitat Autònoma de Barcelona, Institut de Neurociències, Spain There is evidence that the muscarinic activity in several brain regions modulates memory formation of aversively-motivated tasks, although the involvement of the muscarinic receptors (mRs) in the consolidation of two-way active avoidance (TWAA) learning has not been examined. The aim of the present study was to investigate whether the blockade of mRs in the basolateral amygdala (BLA) or ventral hippocampus (vHPC), which receive important cholinergic projections and are involved in aversive learning, affects TWAA consolidation. Immediately after a 30-trial acquisition session (conditioned stimulus: 3-s 60-dB tone, unconditioned stimulus: 0.5-mA footshock), Wistar rats were bilaterally infused with scopolamine (20ìg/site) or phosphate-buffered saline in the BLA or vHPC. Twenty-four hours later, avoidance retention was tested in a 30-trial session. Results showed that there was no difference between the vehicle and scopolamine-injected rats in any measure of shuttle-box performance, indicating that mRs blockade produces no impairment in early memory formation of TWAA learning. Results are discussed in the context of possible occurrence of over-training, which may have a protective effect against scopolamine induced-memory deficits. Conference: 41st European Brain and Behaviour Society Meeting, Rhodes Island, Greece, 13 Sep - 18 Sep, 2009. Presentation Type: Poster Presentation Topic: Poster presentations Citation: Boadas-Vaello P, Carballo-Marquez A, Villarejo-Rodríguez I, Vale-Martinez A, Guillazo-Blanch G and Marti-Nicolovius M (2009). Two-way active avoidance memory consolidation in rats with scopolamine infusions in basolateral amygdala and ventral hippocampus. Conference Abstract: 41st European Brain and Behaviour Society Meeting. doi: 10.3389/conf.neuro.08.2009.09.095 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 08 Jun 2009; Published Online: 08 Jun 2009. * Correspondence: Pere Boadas-Vaello, Universitat Autònoma de Barcelona, Institut de Neurociències, Barcelona, Spain, margarita.marti@uab.es Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Pere Boadas-Vaello Anna Carballo-Marquez Irene Villarejo-Rodríguez Anna Vale-Martinez Gemma Guillazo-Blanch Margarita Marti-Nicolovius Google Pere Boadas-Vaello Anna Carballo-Marquez Irene Villarejo-Rodríguez Anna Vale-Martinez Gemma Guillazo-Blanch Margarita Marti-Nicolovius Google Scholar Pere Boadas-Vaello Anna Carballo-Marquez Irene Villarejo-Rodríguez Anna Vale-Martinez Gemma Guillazo-Blanch Margarita Marti-Nicolovius PubMed Pere Boadas-Vaello Anna Carballo-Marquez Irene Villarejo-Rodríguez Anna Vale-Martinez Gemma Guillazo-Blanch Margarita Marti-Nicolovius Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.