The article analyzes the problems of effective management of labor safety at enterprises. It is noted that the search for methods of justifying management decisions in this area remains relevant from the point of view of theoretical consideration of existing developments and the development of practical recommendations for their implementation at enterprises. Despite the presence of a large number of different approaches to improving management efficiency, based on the theory of decision-making and expert methods, taking into account the cost of implementing this or that variant of the decision, in the vast majority of cases, remains overlooked. A method of conducting an a priori assessment of the effectiveness of decisions is proposed, which involves the formation of a set of alternatives of management decisions, their subsequent expert assessment, as well as the assessment of the cost of their implementation. For a reasoned choice of alternatives, it is suggested to use the indicator of their effectiveness, which is calculated as the ratio of expert assessment to the conditional cost of implementing the alternatives. An example of the application of the developed methodology for one of the enterprises of the mining and metallurgical complex for the justification of measures to reduce the risk of a traumatic event "Contact with an open flame, hot substance or surface" is considered. An alternative is recommended for implementation, which involves increasing the level of technical control of dangerous production factors. For the rational implementation of the proposed methodology at the enterprise, it is necessary to ensure the functioning of the system of accounting and analysis of production factors for the possibility of using these data in the formation of problems that need to be solved. In addition, the implementation of the methodology involves the possibility of involving qualified experts for an objective a priori evaluation of alternatives