Foliar chlorophylls are the most important pigments related to the physiological function of plants. Quantitative estimation of photosynthetic pigments can provide important information about relationships between plants and their environmental conditions. In this study, new spectral indices were designed to enhance spectral resistance to noise, using the area of the spectral curve and axis. The specific area was around the red edge (R daa), instead of the sum of the first derivative of the spectrum, specifically the area of red edge (R da). Meanwhile, three reference indices were also introduced as non-sensitive bands of chlorophylls. The results show that by dividing spectral references, a kind of re-projection, the spectral indices can be calibrated to allow direct and reasonable comparisons of the results. The sensitivity of these reference indices to chlorophylls was also evaluated in this study. The regression results show that R daa and its derivates are highly related to chlorophylls and resistant to noise.