Chloride Atoms Research Articles

Synthesis and characterisation of bismuth(III) phthalocyaninate complex: [BiPc]4[Bi6I11Cl11

A new bismuth(III) phthalocyaninate complex with the formula of [BiPc]4[Bi6I11Cl11] has been obtained in the reaction of pure bismuth filings with phthalonitrile under a stream of iodine monochloride. The complex crystallises in the centrosymmetric space group of the triclinic system. X-ray single crystal analysis revealed that iodine and chloride atoms statistically occupy one of eleven positions of the halogen atoms. Two independent [BiPc]+ cations have similar non-planar conformation. The Bi cation linked to the four N-isoindole atoms of the Pc2− macroring is significantly displaced by 1.117(3)Å and 1.146(2)Å for Bi4 and Bi5, respectively, from the planes defined by those N atoms of the Pc macrocycles. Since bismuth prefers higher coordination number than four, the [BiPc] units interact with three halogen atoms of the [Bi6I11Cl11]4− counter-ion forming centrosymmetric [BiPc]4[Bi6I11Cl11] aggregates. The arrangement of these aggregates in the crystal is determined by the π–π interaction between the phthalocyaninate macrocycles forming the stacking structure along the [111] and [100] directions. The single-crystal conductivity measurements along the stacking [111] and [100] directions gave quite the same values of ∼2.5×10−7Ω−1cm−1 and ∼2.8×10−7Ω−1cm−1, respectively. Temperature dependence of the conductivity exhibits non-metallic character (dσ/dT>0). In addition the compound was characterised by the UV–vis spectroscopy.

Hydrates of Copper Dichloride in Aqueous Solution: A Density Functional Theory and Polarized Continuum Model Investigation

In this work, the hydrates of copper dichloride in gas and aqueous phase have been investigated using the B3LYP method. Low-lying conformers of CuCl(2)(H(2)O)(n) clusters for n = 1-10 were obtained by an extensive conformation search. Contact ion pair (CIP) and solvent-shared ion pair (SSIP) with one dissociated chloride atom (SSIP/s) and SSIP with two dissociated chloride atoms (SSIP/d) all were considered. Our calculations present such a trend that a four-fold CIP conformer is more favorable for CuCl(2)(H(2)O)(n) cluster (n < or = 7) and four-fold SSIP/s for n = 8-10 in the gas phase, while in aqueous solution, more stable structures are five-fold SSIP/s conformer for n = 7-9 and four-fold CIP conformer for n = 2-6. Hydrogen bond (HB) plays an important role in the CuCl(2) solvation, especially HBs formed between the first and second solvation shell water molecules. Electronic absorption spectra of CuCl(2)(H(2)O)(n) clusters were obtained using long-range-corrected time-dependent density functional theory. The calculated electronic absorption peak around 270 nm of CIP conformers is coincident with the absorption of [CuCl(2)](0)(aq) species resolved from the spectra obtained in solutions of trace CuCl(2) (ca. 10(-5) mol/kg) + LiCl (0-18 m), while those of SSIP/s (approximately 250 nm) and SSIP/d (approximately 180 nm) conformers probably correspond to the absorption spectra of [CuCl](+)(aq) and [Cu](2+)(aq) species, respectively. Natural bond orbital charge population analyses show that charge transfer (CT) between a central copper(II) atom and ligands (Cl and H(2)O) increases as the hydrated cluster expands, especially CT from Cu(2+) to the first solvation shell, which enhances the strength of HBs. Such CT becomes more apparent for SSIP structure with the dissociation of chloride ion. OH stretching vibration frequencies of proton donor type water in CuCl(2)(H(2)O)(n) clusters are obviously red-shifted in comparison to those of water clusters, due to CT between the central atom Cu and ligands. SSIP conformers have apparent IR absorption peaks of OH stretching vibration at approximately 3000 cm(-1) for the effect of half-dissociated chloride atoms.

Tetraethylammonium tricarbonylchlorido(pyrazine-2-carboxylato-N1,O)rhenate(I)

In the title complex, (C8H20N)[Re(C5H3N2O2)Cl(CO)3], the ReI atom is coordinated facially by three carbonyl groups; the bidentate pyrazine­carboxyl­ato ligand and a chlorine atom complete the distorted octa­hedral coordination.

Synthesis, characterization and crystal structure of a novel thiazoline/thiazolidine azine ligand and its nickel, copper and zinc complexes

The new ligand N-(2-acetyl-2-thiazoline)- N′-(2-thiazolidin-2-one) azine (ATHTd) has been synthesized and characterized by X-ray diffraction, elemental analysis, 1H and 13C NMR spectra, elemental analysis, IR and UV–Vis spectra. Also the complexes [NiCl(ATHTd)(H 2O) 2]Cl ( 1), [Ni(ATHTd) 2](NO 3) 2·H 2O ( 2), [CuCl 2(ATHTd)] ( 3) and [ZnCl 2(ATHTd) 2] ( 4) have been isolated and characterized in the solid state by X-ray diffraction, elemental analysis, IR spectroscopy, UV–Vis–NIR diffuse reflectance, magnetic susceptibility measurements and, in the case of copper(II) complex, EPR spectroscopy. X-ray data indicate that the environment around nickel atoms in 1 and 2 may be described as a distorted octahedral geometry. In 1 the metal ion is coordinated to one chloride ligand, one water molecule and one ATHTd molecule which acts as a tridentate ligand, while in 2 Ni(II) is coordinated to two tridentate ATHTd molecules. With regard to 3, the coordination geometry around copper(II) ion can be considered a distorted square pyramid with the cation coordinated to one tridentate ATHTd ligand and two chloride ligands. Finally, in the case of 4, the Zn(II) is bonded to two ATHTd molecules that acts as a monodentate ligand and two chloride atoms in a distorted tetrahedral geometry. The structure of ATHTd in the complexes presents an amino-2-thiazoline form instead of the iminothiazolidine one observed in free ATHTd. Another significant structural change in complexes, except in 4, is due to the different degree of rotation of the thiazoline rings around the C(1)–C(4) and C(6)–N(3) bonds, which permit the coordination through thiazolinic nitrogen atoms.

A novel strategy to functionalize carbon nanotubes with cellulose acetate using triazines as intermediated functional groups

An efficient strategy that consists of cutting, chain extension, introducing active groups and homogeneous reaction tactics was employed to functionalize multiwalled carbon nanotubes (MWNTs) with cellulose acetate (CA). Specially, by utilizing 2,4,6-trichloro-1,3,5-triazine, a novel reactive intermediate of the MWNTs, namely triazine-functionalized MWNTs (MWNT- triazine), was obtained. Suitable solubility of the MWNT- triazine makes the next homogeneous functionalization of the MWNTs possible. Detailed characterizations further verified that reaction between chloride atoms in the MWNT- triazine and hydroxyl groups in the CA had contributed to the formation of MWNT- CA conjugates. With a nanotube-attached CA content of 42.8 wt.%, the MWNT- CA is readily soluble in intensive polar solvents. Confirmation of the CA-functionalized MWNTs might lead to further studies aiming at potential applications in specific sorption and isolation.

Solvothermal synthesis, characterization and properties of [ReCl5(py)]− complex with T (Néel) of 5.5 K

The synthesis and properties of a rhenium(IV) complex with pyridine as a ligand are presented. The complex, with the formula (2-methyl-pyH)[ReCl5(py)] 4,4′-bipyridyl 1 has been characterized by elemental analysis, IR spectroscopy, SQUID and X-ray measurements. The single crystal X-ray structure of 1 shows that the rhenium center is of distorted octahedral environment, consisting of five chloride atoms and one pyridine ligand. The solid-state magnetic measurements show antiferromagnetic interactions with T (Neel) of 5.5 K.

Plasmonic photocatalytic system using silver chloride/silver nanostructures under visible light

Plasmonic photocatalytic nanostructured system was investigated on silver chloride/silver nanoparticles under visible light. Silver chloride/silver nanoparticles were readily prepared using dispersing agent and light irradiation. The d-spacing analysis, high resolution-transmission electron microscopy, X-ray diffraction analysis and diffuse-reflectance spectroscopy demonstrated that silver nanoparticles were introduced on the surface of silver chloride nanoparticles and then silver chloride/silver nanostructured photocatalytic materials were successfully synthesized. The as-synthesized plasmonic photocatalysts exhibited the enhanced photocatalytic performance over nitrogen-doped titania nanomaterials. The improved catalytic activity was originated from the enhanced adsorption for visible light, electron–hole separation, and the formation of chloride atoms in silver chloride/silver nanostructured materials.

Synthesis and characterization of thiosemicarbazone derivatives of 2-chloro-4-hydroxy-benzaldehyde and their rhenium(I) complexes

N-Thioamide thiosemicarbazone derived of 2-chloro-4-hydroxy-benzaldehyde (R = H, HL 1; R = Me, HL 2 and R = Ph, HL 3) have been prepared and their reaction with fac-[ReX(CO) 3(CH 3CN) 2] (X = Br, Cl) in chloroform gave the adducts [ReX(CO) 3(HL)] ( 1a X = Cl, R = H; 1a′ X = Br, R = H; 1b X = Cl, R = CH 3; 1b′ X = Br, R = CH 3; 1c X = Cl, R = Ph; 1c′ X = Br, R = Ph) in good yield. Complexes 1a′ and 1b’ were also obtained by the reaction of HL 1 and HL 3 with [ReBr(CO) 5] in toluene. All the compounds have been characterized by elemental analysis, mass spectrometry (FAB), IR and 1H NMR spectroscopic methods. Moreover, the structures of HL 2, HL 3 and 1a·H 2O were also established by X-ray diffraction. In 1a, the rhenium atom is coordinated by the sulphur and the azomethine nitrogen atoms, forming a five-membered chelate ring, as well as three carbonyl carbon and chloride atoms. The resulting coordination polyhedron can be described as a distorted octahedron. The study of the crystals obtained by slow evaporation of methanol and DMSO solutions of the adducts 1a′ and 1b, respectively, showed the formation of dimer structures based on rhenium(I) thiosemicarbazonates [Re 2(L 1) 2(CO) 6]·3H 2O ( 2a)·3H 2O and [Re 2(L 2) 2(CO) 6]·(CH 3) 2SO ( 2b)·2(CH 3) 2SO. Amounts of these thiosemicarbazonate complexes [Re 2(L) 2(CO) 6] ( 2) were obtained by reaction of the corresponding free ligands with [ReCl(CO) 5] in dry toluene. In 2a·3H 2O and 2b·2(CH 3) 2SO the dimer structures are established by Re–S–Re bridges, where S is the thiolate sulphur from a N,S-bidentate thiosemicarbazonate ligand. In both structures the rhenium coordination sphere is similar; the dimers are in the same diamond Re 2S 2 face.

Homogeneous modification of carbon nanotubes with cellulose acetate

An efficient strategy that comprised shorten, chain extension, active groups introducing and homogeneous reaction tactics, was adopted to modify multiwalled carbon nanotubes (MWNTs) with cellulose acetate (CA). Specially, by utilizing 2,4,6-trichloro-1,3,5-triazine, a reactive intermediate of the MWNTs (MWNT-triazine) was obtained. Suitable solubility of the MWNT-triazine helps make the homogeneous modification become reality. Detailed characterizations further verified that reaction between chloride atoms in the MWNT-triazine and hydroxyl groups in the CA had contributed to the formation of MWNT-CA conjugates. The novel MWNT-CA consists of carbon (76.3%), oxygen (18.4%) and nitrogen (5.3%). With a nanotube-attached CA content of 42.8 wt%, the MWNT-CA is readily soluble in DMSO, NMP, DMF and DMAc. Confirmation of the CA-based modification route might lead to studies aiming for specific sorption and isolation.

Structure of 3,4-dicarboxy-1-methylpyridinium chloride studied by X-ray diffraction, DFT calculations, NMR and FTIR spectra

The structure of 3,4-dicarboxy-1-methylpyridinium chloride (34DCMPCl) has been studied by X-ray diffraction, DFT calculations, NMR and FTIR spectra. The crystals are monoclinic, space group P2 1. Chloride anion links two 3,4-dicarboxy-1-methylpyridinium cations into infinite zigzag chains down [0 1 0] by the OH⋯Cl −⋯HO hydrogen bonds of 2.953(2) and 2.968(2) Å. Hydrogen bonds in single molecules optimised by the B3LYP/6-31G(d,p) approach depend on the environment. In vacuum ( 2 and 3) the hydrogen bonded proton is linked with chloride atom (Cl–H⋯O), while in DMSO ( 4) the structure is similar to that in the crystal (Cl⋯H–O). Linear correlations between the experimental 13C and 1H chemical shifts ( δ exp) of the investigated compound in DMSO-d 6 and the calculated GIAO/B3LYP/6-31G(d,p) magnetic isotropic shielding tensors ( σ calc) using the screening solvation model (COSMO), δ exp = a + bσ calc, are reported. The FTIR spectrum of the solid compound is consistent with the X-ray structure. The deformation absorptions in plane and out of plane, both in FTIR and second-derivative spectra (d 2), appear as two bands and confirm the OH⋯Cl −⋯HO hydrogen bonds formation.

Synthesis, characterization, thermal properties and flame retardancy of a novel nonflammable phosphazene-based epoxy resin

Hexakis(4-hydroxyphenoxy)-cyclotriphosphazene (PN–OH) was synthesized through nucleophilic substitution of the chloride atoms of hexachlorocyclotriphosphazene and reduction of the aldehyde groups, and its chemical structure was characterized by elemental analysis, 1H and 31P NMR, and Fourier transform infrared (FTIR) spectroscopy. A new phosphazene-based epoxy resin (PN-EP) was successfully synthesized through the reaction between diglycidyl ether of bisphenol-A (DGEBA) and PN–OH, and its chemical structure was confirmed by FTIR and gel permeation chromatography. Four PN-EP thermosets were obtained by curing with 4,4′-diaminodiphenylmethane (DDM), dicyandiamide (DICY), novolak and pyromellitic dianhydride (PMDA). The reactivity of PN-EP with the four curing agents presents an increase in the order of DDM, PMDA, novolak and DICY. An investigation on their thermal properties shows that the PN-EP thermosets achieve higher glass-transition and decomposition temperatures in comparison with the corresponding DGEBA ones while their char yields increase significantly. The PN-EP thermosets also exhibit excellent flame retardancy. The thermosets with novolak, DICY and PMDA achieve the LOI values above 30 and flammability rating of UL94 V-0, whereas the one with DDM reaches the V-1 rating. The nonflammable halogen-free epoxy resin synthesized in this study has potential applications in electric and electronic fields in consideration of the environment and human health.

Heteroleptic binuclear palladium(ii) and platinum(ii) complexes containing 1,2-bis(diphenylphosphino)acetylene and 1,2-benzenedithiolates: syntheses, crystal structures, electrochemistry and photoluminescence properties

A series of heteroleptic binuclear Pd(ii) and Pt(ii) complexes, [M(bdts)](2)(micro-dppa)(2) (M = Pd () and Pt (); dppa = 1,2-bis(diphenylphosphino)acetylene = Ph(2)PC[triple bond, length as m-dash]CPPh(2); bdts = 1,2-benzenedithiolate (bdt: a), 3,4-toluenedithiolate (tdt: b) and 1,4-dichloro-2,3-benzenedithiolate (Cl(2)bdt: c), containing two square-planar MP(2)S(2) cores were prepared using (MCl(2))(2)(micro-dppa)(2) (M = Pd () and Pt ()) and the corresponding 1,2-benzenedithiols, and characterized by spectroscopic methods including FT-IR, Raman, UV-vis, MALDI-TOF-MS, (31)P{(1)H} and/or (195)Pt{(1)H} NMR spectroscopy. X-Ray crystal structure analyses for complexes and revealed that C1C2C4C3 is twisted in two ways with a torsion angle of 21.6-30.7 degrees for 3a, 4a, and 4b and about 42 degrees for 3c and 4c, and that their crystals are racemic mixtures. Due to the more electronegative chloride atoms in the ligand, complexes and show higher nu(M-S) vibrational frequencies in their Raman spectra, smaller spin-spin coupling constants (J(Pt-P)) in their (195)Pt{(31)P} NMR spectra and higher anodic potentials (E(pa)) in their cyclic voltammograms than complexes 3a, 3b, 4a and 4b. Moreover, only complex containing the chlorinated ligand and Pt(ii) ion exhibits luminescence (lambda(ob) = 610 nm and lambda(ex) = 440 nm) in the solid state at 298 K. This emissive transition can be assigned as the d-pi(dithiolate) metal-to-ligand charge transfer (MLCT) and the feasibility of this spin-forbidden transition is ascribed to the effective spin-orbit coupling of ligand c containing heavy chloride atoms and the large spin-orbit coupling in Pt(ii).

1,3-Bis(thio-phen-2-ylmeth-yl)-3,4,5,6-tetra-hydro-pyrimidinium trichlorido(η-p-cymene)ruthenate(II).

The asymmetric unit of the title compound, (C14H17N2S2)[Ru(C10H14)Cl3], contains a 1,3-bis­(thio­phen-2-ylmeth­yl)-3,4,5,6-tetra­hydro­pyrimidinium cation and a trichlorido(η6-p-cymene)ruthenate(II) anion. The Ru atom exhibits a distorted octa­hedral coordination with the benzene ring of the p-cymene ligand formally occupying three sites and three chloride atoms occupying the other three sites. The N—C bond lengths of the N—C—N unit of the pyrimidinium cation are shorter than the average single C—N bond length of 1.48 Å, thus showing double-bond character, indicating a partial electron delocalization within the N—C—N fragment. The pyrimidine ring has an envelope conformation. Four inter­molecular C—H⋯Cl hydrogen bonds generate a three-dimensional hydrogen-bonded framework.

Crystal Structure of Antitubercular Complex: cis-(chloro)-[N,N′-bis-(diethyl-2,2′-bipyridine-3,3′-dicarboxylate)]ruthenium(II) Monohydrate

Diethyl-2,2′-bipyridine-3,3′-dicarboxylate (3 or L) reacts with RuCl3 · 3H2O to give cis-(Cl)-[Ru(L)2Cl2] · H2O (4) and structure of the complex was determined by spectral (IR, 1H-NMR), and mass spectroscopic data, elemental analyses and X-ray crystallography. The structure is solved in triclinic, space group p-1 with a = 10.658 (2), b = 12.446 (3), c = 14.186 (5) A, α = 104.856 (3), β = 108.704 (3), γ = 94.973 (2)°, V = 1693.2 (8) A3, Z = 2 with final R = 0.012. The geometry of the complex is shown to be a distorted octahedral with four nitrogens of two 2,2′-bipyridyl ligands in two different planes with Ru–N distance as 2.021 (2)−2.071 (3) A. The cis-position is occupied by two chloride atoms with Ru–Cl distance as 2.4156 (12) and 2.4167 (13) A. The trans-axial Cl2–Ru1–N and Cl1–Ru1–N4 angles are respectively, 172.42 (7) and 174.12 (7)°. A weak hydrogen bonding is observed between the two chlorides and hydrogens of neighbouring molecule [C–H···Cl distance as 2.72, 2.77 (4) A]. A second type of weak hydrogen bonding is also observed between the oxygens of carboxylate groups and hydrogens of a neighbouring molecule [C–H···O distance as 2.53, 2.56 and 2.34 (4) A]. The structure of anti-tubercular precursor complexes, cis-(chloro)-[N,N′-bis-(diethyl-2,2′-bipyridine-3,3′-dicarboxylate)]ruthenium(II) monohydrate is solved by single crystal X-ray diffraction analysis which reveals geometry of the complex to be a distorted octahedral with four nitrogens of two 2,2′-bipyridyl ligands in two different planes. The cis-position is occupied by two chloride atoms.

Dynamics of fractional condensation of a substance on a probe for spectral analysis

The fractional separation of trace metals on a cold tungsten probe from salt matrix vapor, which interferes with the spectral analysis, is studied. The spatial structure of the vapor flows of sodium chloride, potassium sulfate, and indium atoms is visualized at characteristic wavelengths as they interact with the probe. The vapor flow rate and the probe orientation were varied. It is found that the smoke of the matrix does not prevent the deposition of the metal on the probe because of spatial separation of these fractions and that the detrimental effect of thermal gas expansion and other factors is eliminated. The sensitivity of the atomic absorption analysis of indium impurities in these salts is increased by an order of magnitude.

Crystal and Molecular Structure of Dichloro(ethylenediamine)gold(III) Nitrate: [Au(NH2CH2CH2NH2)Cl2]NO3.

The gold(III) atom in [Au(NH2CH2CH2NH2) Cl2]NO3 is chelated by the ethylenediamine (en) ligand and the approximately square planar geometry is completed by two chloride atoms. Weak Au⋯O and Au⋯Cl contacts are noted above and below the square plane leading to a tetragonally distorted octahedron for the gold(III) center. Extensive charge-assisted hydrogen bonding of the type N-H⋯O leads to the formation of a 2-D array and layers are consolidated into a 3-D network via C-H⋯O and C-H⋯Cl contacts. The compound crystallizes in the orthorhombic space group Pbca with a = 10.3380(11) Å, b = 8.2105(7) Å, c = 19.625(2) Å, and Z = 8.

First donor stabilized-phosphenium rhodium complexes

The coordination properties of a donor stabilized-phosphenium adduct have been examined in rhodium chemistry. The preparation as well as the characterization of the first examples of donor stabilized-phosphenium rhodium(I) complexes is reported in this paper. Indeed, mono- and di-cationic rhodium complexes were obtained in quantitative yield by the direct addition of this imidazolium P(III)-ligand to [RhCl(1,5-COD)] 2 in CH 2Cl 2 solution with a 1:1 P/Rh ratio under argon and 2:1 P/Rh ratio under CO atmosphere, respectively. Crystal structure of the bis-cationic donor stabilized-phosphenium rhodium(I) complex has been obtained from an acetone/pentane mixture. Its molecular structure has revealed a particular arrangement in which the chloride atom is sandwiched between both imidazolium rings as a result of the electrostatic attractive interactions between the electron-deficient heterocarbene moieties and the electron rich halide atom. On the other hand, the basicity of N-donor-phosphenium adducts has been evaluated by measure of the CO stretching frequency in one rhodium complex, and was found halfway between the phosphites and the strong π-acceptor phosphines.

Jacobsen’s Catalyst Interaction with Polydimethylsiloxane/Tetraethoxysilane Network and Solvent Molecules: Theoretical Design of a New Polymeric Membrane

Theoretical calculations were used for understanding the occlusion of the Jacobsen’s catalyst inside a polydimethylsiloxane/tetraethoxysilane (PDMS/TEOS) polymeric membrane. Our analysis indicates there is a partition equilibrium of the catalyst between the solvent and the swelled membrane. Density functional theory calculations at the B3LYP level predict interaction energies of the Jacobsen’s catalyst with benzene, chlorobenzene, dichloromethane, tetrahydrofuran, and acetone and with a model of PDMS chain in the range of 6−8 kcal mol−1. For methanol, the hydrogen bonding involving the coordinated chloride atom reaches 14 kcal mol−1. These findings were used for designing a new membrane, where a diol structure was added to the side of the polymeric chain. The modified membrane should present improved retention properties.

Small Neutralizing Molecules to Inhibit Actions of the Chemokine CXCL12

The chemokine CXCL12 and the receptor CXCR4 play pivotal roles in normal vascular and neuronal development, in inflammatory responses, and in infectious diseases and cancer. For instance, CXCL12 has been shown to mediate human immunodeficiency virus-induced neurotoxicity, proliferative retinopathy and chronic inflammation, whereas its receptor CXCR4 is involved in human immunodeficiency virus infection, cancer metastasis and in the rare disease known as the warts, hypogammaglobulinemia, immunodeficiency, and myelokathexis (WHIM) syndrome. As we screened chemical libraries to find inhibitors of the interaction between CXCL12 and the receptor CXCR4, we identified synthetic compounds from the family of chalcones that reduce binding of CXCL12 to CXCR4, inhibit calcium responses mediated by the receptor, and prevent CXCR4 internalization in response to CXCL12. We found that the chemical compounds display an original mechanism of action as they bind to the chemokine but not to CXCR4. The highest affinity molecule blocked chemotaxis of human peripheral blood lymphocytes ex vivo. It was also active in vivo in a mouse model of allergic eosinophilic airway inflammation in which we detected inhibition of the inflammatory infiltrate. The compound showed selectivity for CXCL12 and not for CCL5 and CXCL8 chemokines and blocked CXCL12 binding to its second receptor, CXCR7. By analogy to the effect of neutralizing antibodies, this molecule behaves as a small organic neutralizing compound that may prove to have valuable pharmacological and therapeutic potential.

Synthesis of adaptative and amphiphilic polymer model conetworks by versatile combination of ATRP, ROP, and “Click chemistry”

Well-defined adaptative and amphiphilic polymer conetworks based on hydrophilic poly(N,N-dimethylamino-2-ethyl methacrylate) (PDMAEMA) and hydrophobic poly(e-caprolactone) (PCL) have been prepared by combination of ATRP, ROP, and Click chemistry. Telechelic α,ω-alkyne terminated PCL crosslinker was obtained by ring-opening polymerization (ROP) of CL in THF at 80 °C initiated by 1,4-butanediol and catalyzed by tin(II) bis 2-ethyl hexanoate (Sn(Oct) 2 ), followed by the quantitative esterification of hydroxyl end-groups by activated 4-pentynoic acid. In parallel, an azido-containing PDMAEMA-based copolymer was obtained in a three-step strategy involving primarily the copolymerization of DMAEMA with newly synthesized 2-(2-azidoethoxy)ethyl methacrylate (AEEMA) monomer. The latter was obtained by nucleophilic substitution of chloride atom from 2-(2-chloroethoxy)ethanol by an azide group followed by the esterification reaction of the hydroxyl group with methacrylic anhydride. The copolymerization was carried out in an equivolumic mixture of H 2 O and isopropanol at r.t. and initiated by a ω-bromoisobutyryl oligo PEO macroinitiator in the presence of various ligated copper(I)-based catalysts. In a last step, both polymer precursors were chemically linked by the Huisgen-1,3-dipolar cycloaddition in anhydrous THF at r.t. using CuBr complexed by 2,2'-bipyridine ligand as catalyst. Final material was characterized by the means of DSC and SEM, both attesting of a homogeneous distribution of the PCL crosslinkers and a highly porous structure in this new amphiphilic model conetworks.