We present a string-based picture of the cosmological evolution in which (CP-violating) gravitational anomalies acting during the inflationary phase of the universe cause the vacuum energy density to “run” with the effective Hubble parameter squared, [Formula: see text], thanks to the axion field of the bosonic string multiplet. This leads to baryogenesis through leptogenesis with massive right-handed neutrinos. The generation of chiral matter after inflation helps in cancelling the anomalies in the observable radiation- and matter-dominated eras. The present era inherits the same “running vacuum” structure triggered during the inflationary time by the axion field. The current dark energy is thus predicted to be mildly dynamical, and dark matter should be made of axions. Paraphrasing Carl Sagan [ https://www.goodreads.com/author/quotes/10538.Carl_Sagan .]: we are all anomalously made from starstuff.