Due to its convenience and affordability, chipless RFID technology has become increasingly popular for detecting environmental temperature and humidity. This paper presents a wireless chipless RFID sensor for measuring temperature and humidity. The sensor utilizes a composite material consisting of Fe2O3-Co3O4、SnO2、and rGO to achieve accurate detection of both temperature and humidity. We investigated the change of RFID resonance frequency under different temperature and humidity variations. The temperature and humidity sensitive material is coated on the surface of the antenna by spinning coating machine. The combined structure of nanoparticle-attached rods of Fe2O3-Co3O4, granular clusters of SnO2 and flakes of rGO enhances the sensor’s sensitivity to temperature and humidity measurements. The sensitivity of the temperature and humidity sensor is approximately-0.293 MHz/°C and −2.12 dB/°C during a change in ambient temperature from 10 °C to 85 °C, and approximately −2.11 MHz/°C and 0.19 dB/%RH during a change in humidity from 10 %RH to 65 %RH at normal ambient temperature. The response time of the temperature and humidity sensor to temperature and humidity changes is 15.3 s and 10.1 s, and the recovery time is 21.7 s and 17.5 s, respectively. The wireless chipless RFID sensor has good sensitivity and responsiveness for temperature and humidity measurements.