Background: Pathophysiology plays a pivotal role in medical education by bridging basic sciences and clinical medicine. However, traditional teaching approaches in China often lack integration between theory and clinical practice, hampering postgraduates' understanding of disease mechanisms and diagnostic abilities. This study explores innovative strategies to effectively integrate theory and practice, enhancing Chinese medical postgraduates' learning.Methodology: A comprehensive literature review analyzed the current educational landscape and identified innovative teaching strategies aligning theoretical concepts with clinical applications. The implementation methods and potential to foster autonomous and innovative learning were examined.Results: Several student-centred strategies were identified, including problem-based learning (PBL), case-based learning (CBL), flipped classrooms, and integrated teaching models. These approaches emphasize active learning, critical thinking, and applying theoretical knowledge to clinical scenarios. Adopting these strategies can improve postgraduates' learning efficiency, problem-solving abilities, and clinical reasoning skills while promoting self-directed learning and innovative thinking.Conclusion: Integrating theory and practice through innovative teaching strategies is crucial to enhance the quality of pathophysiology postgraduate education in China. Educators should implement student-centred approaches like PBL, CBL, flipped classrooms, and integrated models to stimulate autonomous learning and cultivate innovation. Providing opportunities for active learning and clinical application can significantly improve postgraduates' learning outcomes and preparedness for future practice. Further research evaluating the long-term impact on postgraduate performance and patient care is warranted.