The objective of this study was to evaluate the effects of using the Saccharomyces cerevisiae yeast cell wall (YCW) as an aflatoxin B<sub>1 </sub>(AFB<sub>1</sub>) adsorbent in broiler chicken feed on performance and carcass characteristics. The present study used a randomized complete block with four treatments in a 2 (with or without AFB<sub>1</sub>) × 2 (with or without YCW) factorial design. No interaction effect (P &gt; 0.05) between AFB<sub>1</sub> and YCW was found on the studied performance variables. The addition of YCW to the diets stimulated the feed intake of chickens during 1–21 days of age. However, YCW did not significantly increase (P &gt; 0.05) weight gain nor did it change feed conversion. The presence of AFB<sub>1</sub> in the diet did not affect (P &gt; 0.05) performance parameters. The addition of YCW to the feed containing AFB<sub>1</sub> significantly increased (P &lt; 0.05) the post-fasting live weight (781.12 g), chilled carcass weight (554.41 g), and leg weight (163.34 g) compared to feed without AFB<sub>1</sub> and YCW (764.84 g; 533.41 g; 161.88 g), feed with only YCW (764.22 g; 546.87 g; 159.34 g), and feed with only AFB<sub>1</sub> (735.41 g; 510.56 g; 152.75 g). In conclusion, YCW effectively reduced some of the deleterious effects of AFB<sub>1</sub> in broilers.