An urgent issue today is the increase in the number of children with mental retardation. Statistics from the last five years show that more than 20% of children are born with lesions of the central nervous system. Perinatal pathology leads to a delay in mental and motor development and subsequently contributes to the risk of children's academic failure, maladjustment and social deviation. For a comprehensive solution to the problem, rehabilitation methods should be correctly selected, aimed at improving mental functions, developing physical qualities and forming motor skills. The purpose of the study is to study the effectiveness of an interactive physical education complex in the rehabilitation of children with mental retardation. The results obtained made it possible to identify the effectiveness of the use of a non–drug rehabilitation method - an interactive physical education complex for the development of cognitive functions and physical qualities of primary school children with mental retardation. To identify the level of logical thinking, the "Exclusion of excess" method was used, dexterity of movements was assessed by the "Darts" test, communicative activity was identified using a questionnaire for parents using the Makarchuk A.V., Gorinova E.V. method, large hand motor skills were assessed by a functional motor test, fine hand motor skills were assessed by the Grizik T.I., Tymoshchuk L.F. method. In the study of logical thinking in children after the rehabilitation course, an increase in the average values of the indicator was revealed in the main group, there were no changes in the control group. The results of the dexterity assessment test showed that after rehabilitation, the average values of the indicator increased only in the main group where the interactive complex was used. When evaluating communicative activity, it was revealed that when comparing groups, no changes were found in the average values of the indicator, however, the level of social interaction in the main group moved from "average" to "high" on a point scale, in the control group the level remained the same. When evaluating large hand motor skills, it was revealed that after rehabilitation in the main group, in which an interactive physical education complex was used, the average values of the indicator increased and began to correspond to the assessment "good", in the control group the indicator did not change – the assessment "satisfactory". In the study of fine motor skills, an increase in the average values in the main group was revealed: from the level of "poor development" to the level of "insufficiently good development", there were no changes in the control group. Thus, the interactive physical education complex increases the indicators of logical thinking, dexterity of movements, large and small hand motor skills and improves the level of communicative activity.