Child Maltreatment Research Articles

Characteristics and Circumstances of Suicide Among Children Aged 6 to 9 Years: 2006-2021.

Limited research exists on suicide among children aged 5 to 9 years. The objective of this study was to examine characteristics of suicide in children younger than 10 years. Data are from the National Fatality Review-Case Reporting System (NFR-CRS) for years 2006 through 2021 for children aged 6 to 9 years who died by suicide. No suicide deaths were reported in NFR-CRS for children aged ≤ 5 years. Descriptive analyses by demographics and circumstances were conducted. A thematic analysis of prevention recommendations made by child death review teams was performed. From 2006 to 2021, NFR-CRS identified 78 suicide decedents aged 6 to 9 years. The largest share were aged 9 years (72%), male (74%), non-Hispanic Black (42%), and died by hanging (86%) at home (91%). School-related problems (39%), history of child maltreatment (36%), history of mental health services (30%), argument with parents (23%), and familial discord (19%) were common circumstances. Key suicide prevention themes included education for caregivers and school staff, improved behavioral health services, and implementation of school policies and programs. Results provide a more complete picture of suicide among younger children, improving understanding of their unique characteristics. It is recommended that program planners consider both age-appropriateness and the impacts of social (eg, racism) and structural inequities in their approaches to prevention, encompassing both community and school-based strategies. For pediatricians, results emphasize the importance of lethal means counseling, safety planning, and educating parents and caregivers on the distinct warning signs of suicide for younger children.

The Circumstances Surrounding Fatal Pediatric Opioid Poisonings, 2004-2020.

There is little understanding of the circumstances behind fatal pediatric opioid poisonings. Our objective was to characterize opioid fatalities according to child, family, and household factors. We used data from the National Fatality Review-Case Reporting System to describe the circumstances behind the deaths of children 0 to 17 years of age who died of an opioid poisoning (ie, prescription opioid, heroin, illicit fentanyl) between 2004 and 2020. Decedents were stratified into age groups: 0-4, 5-9, 10-14, and 15-17 years. The majority (65.3%) of the 1696 fatal opioid poisonings occurred in the child's own home. Prescription opioids contributed to 91.8% of deaths, heroin contributed to 5.4%, and illicit fentanyl to 7.7%. Co-poisonings with nonopioid substances occurred in 43.2% of deaths. Among 0- to 4-year-olds, 33.9% died of homicide and 45.0% had a primary caregiver with a history of substance use/abuse. Among 10- to 14-year-olds and 15- to 17-year-olds, respectively, 42.0% and 72.8% of decedents had a history of substance use/abuse. In each age group, at least 25.0% of children were victims of previous child maltreatment. A history of maltreatment and substance use-whether on the part of the caregiver or the child-are common factors surrounding fatal pediatric opioid poisonings, the majority of which occur in the child's own home. Families with children of all ages would benefit from interventions focused on opioid prescribing, storage, disposal, and misuse. These findings also underscore the urgency of ensuring that access to naloxone becomes universal for families with a history of maltreatment and/or substance use.

Mediation of DNA methylation (cg04622888 and cg05037505) in the association between childhood maltreatment and non-suicidal self-injury in early adolescents.

It is unclear whether DNA methylation underlies the association between childhood maltreatment (CM) and non-suicidal self-injury (NSSI) in early adolescents. We aim to explore the mediation of specific DNA methylation sites in the associations of CM and its subtypes with NSSI, following investigation on the association between specific DNA methylation sites and NSSI. A case-control study was conducted to examine 155 adolescents aged 12-14years who were identified to have engaged in NSSI and 201 controls. CM and its subtypes were evaluated by using the Childhood Trauma Questionnaire. The EPIC 850k Bead Chip was used to discover differential methylation sites (DMSs) in the peripheral blood between 10 NSSI cases and 10 controls. Targeted pyrosequencing was employed to detect the levels of specific DMSs among the total study population, which were selected based on bioinformatics analyses and literature review. We discovered 456 DMSs between NSSI cases and controls, 219 were hypermethylated and 237 were hypomethylated. After controlling for potential confounders, CM or its subtypes, and the methylation of cg04622888 and cg05037505 were all significantly associated with NSSI (all P < 0.05). The total association of CM and its subtypes with NSSI were all significantly (all P < 0.05), with the standardized coefficient (β) ranged from 0.12 for physical neglect to 0.24 for emotional neglect and CM. Significant indirect association of physical neglect with NSSI through methylation of cg04622888 was observed and the mediating proportion was 0.14 (95%CI 0.06-0.23). Significant indirect associations of emotional abuse, emotional neglect, and physical neglect with NSSI through methylation of cg05037505 were also observed, and the mediating proportions were 0.09 (95%CI 0.04-0.14), 0.08 (95%CI, 0.03-0.14) and 0.19 (95%CI 0.07-0.32), respectively. Data of this study suggested thatmethylation of cg04622888 and cg05037505 were independently associated with NSSI among early adolescents, and they partially mediated the associations of emotional abuse, emotional neglect, and physical abuse with NSSI.

Emotional awareness, child maltreatment and child exposed to intimate partner violence: A systematic review of their relationship with symptoms and protective factors

AbstractThis systematic review studies the emotional awareness (EA) in children exposed to intimate partner violence (IPV) and other child maltreatment (CM), and their relationship with externalizing and internalizing symptoms and protective factors. The search was performed using the PubMed, PsycINFO and Google Scholar databases. The search was based on scientific studies using the follow terms: (“emotional awareness” OR “emotional intelligence”) AND (child OR adolescent OR children OR teenager) AND (abuse OR neglect OR maltreatment OR “presence of domestic violence” OR “domestic violence” OR “intimate partner violence”). Seventeen empirical studies were included, presenting a low risk of bias (82%). Four studies have explored the relationship between EA and exposition to IPV, four with sexual abuse, five with neglect, five with psychological abuse and three with physical abuse. A total of 13 articles have assessed the relationship between EA and externalizing and internalizing symptoms: three with suicidal ideation (SI), three with post‐traumatic stress symptoms (PTSD), two focused on addictions, three on affective symptoms, one with total externalizing symptoms, one with borderline personality disorder (BDP), one with non‐suicidal self‐injury (NSSI) and one with disordered eating behaviours and attitudes (DEBA). Studies show that abused children have lower EA and that the lower EA, the greater the presence of symptoms. A total of 10 articles have assessed the relationship between EA and protective factors such as mental health in parents, six with coping skills, one with self‐stem and one with quality of life. The main results suggest that EA could be a mediator between children exposed to IPV and other CM and internalizing and externalizing symptoms as well as protective factors.

Efektivitas Pelatihan Mindful Parenting Terhadap Penurunan Kecenderungan Child Maltreatment pada Anak Usia Dini

Child maltreatment is a risky act and it has a serious impact, especially for early childhood. Mindful parenting training is one of the parenting concepts that can minimize the occurrence of child maltreatment. This study aims to examine the effectiveness of mindful parenting training on reducing the tendency of child maltreatment in parents. This study uses a pre-experimental design method with a one group pre-test-post-test design. The sample selection was determined using purposive sampling technique. The subjects in this study amounted to 35 parents of students at Aisyah Integrated Birrul Walidain Kindergarten in Kudus, Central Java. Hypothesis testing was conducted using paired sample t-test, where a significance value of P = 0.000 (P &lt; 0.05) was obtained, which means that the hypothesis is accepted. In other words, mindful parenting is effective in reducing the tendency of child maltreatment by parents in early childhood.

Young Adults with a History of Residential Youth Care: A Cohort Profile of a Hard-to-Reach Population

Adults with a history of living in residential youth care (RYC) face elevated risks across various life domains. In this cohort profile paper, we outline the design of a comprehensive follow-up study—the VINGO study—targeting young adults (22–30 years) with a history of living in RYC (T2). We describe the recruitment strategy and present sample characteristics. Data were collected in the baseline study (T1) from 2011 to 2014. At T1, the 400 adolescent participants showed a high prevalence of mental disorders, maltreatment experiences, substance use, and self-reported suicide attempts. Data collection at T2 10 years later (2021–2023) included self-reported sociodemographic information, physical health, childhood maltreatment, dissociation, quality of life, social support, and self-esteem using standardized and validated instruments. A diagnostic psychiatric assessment and subjective evaluation of service utilization were conducted by telephone interviews. Additionally, a qualitative sub-study involved in-depth interviews of fourteen participants. We reached a 52% response rate at T2. Comparing participants (n = 157, 107 females) to non-participants (n = 243, 123 females) based on T1 data revealed that T2 participants had a higher prevalence of depression, anxiety, and conduct disorder and a lower prevalence of ADHD at T1. Furthermore, T2 participants reported more suicide attempts, experiences of maltreatment, and problematic substance use at T1. Our results show that we reached a burdened population, positioning the VINGO study as a unique opportunity to examine a vulnerable population of emerging adults.

Lingering shadows of childhood corporal punishment: Family trajectories across decades

AbstractObjectiveCorporal punishment is the most common form of violence against children worldwide. This study adopts a life course perspective to examine associations between childhood corporal punishment and distinct multi‐decade family trajectories from young adulthood to middle adulthood in China. Specifically, it examines how childhood parental punishment shapes later family life course trajectory patterns, incorporating partnership, marriage, and fertility outcomes, and considers different sources of punishment (maternal and paternal) and potential gender differences (sons and daughters).BackgroundAccumulating evidence reveals that corporal punishment is not only unnecessary as a disciplinary technique but also harmful to children. This evidence has led to a worldwide movement to eliminate any non‐accidental use of physical force against children. However, previous research often assesses isolated family outcomes without considering family development as a dynamic and interconnected process, resulting in an ambiguous understanding of childhood corporal punishment's long‐reaching influence on unfolding family pathways.ResultsResults uncovered both stability and diversity in Chinese family trajectories, with the majority following stable marital norms. Experiencing childhood corporal punishment increased the odds of an early unstable trajectory characterized by divorce and remarriage. Moreover, the implications of childhood paternal punishment appeared more wide‐ranging than maternal punishment in terms of sorting into normative versus atypical family trajectory patterns. Childhood maltreatment also overrides influences of child gender, similarly impacting future family trajectories across genders.ConclusionThis research highlights the profoundly disruptive effects of corporal punishment on family development throughout the lifespan, carrying important implications for fostering healthier and more resilient families.

Pre-school and primary teachers in the process of detecting child maltreatment in Andalusia (Spain) / El profesorado de Infantil y Primaria en el proceso de detección del maltrato infantil en Andalucía (España)

This study analyses teachers’ knowledge about child maltreatment in the family and explores their professional background in dealing with this problem. 227 pre-school and primary teachers from Andalusia (Spain) participated in the study. The majority of the teachers had never reported a case of child maltreatment during their professional background. These situations were experienced by the teachers with high levels of emotional impact, and both they and their schools showed high levels of involvement in cases identified. Three teacher profiles were identified, the group of trained teachers being the most capable of identifying more complex signs of child maltreatment, followed by those with more years of seniority. The process of detection and reporting of child maltreatment in the school setting is complex, and a wide range of elements need to be analysed conjointly.

Impact of childhood maltreatment on mental health in Australia: a novel meta-analytic approach combining epidemiological data.

Impact of childhood maltreatment on mental health in Australia: a novel meta-analytic approach combining epidemiological data.

A Preliminary Investigation of a Conceptual Model Describing the Associations Between Childhood Maltreatment and Alcohol Use Problems

Background/Objectives: Childhood maltreatment has been linked to numerous adverse outcomes in adulthood, including problem substance use. However, not all individuals exposed to childhood maltreatment develop substance use problems, indicating the role of other factors in influencing this outcome. Past work suggests that adverse early life experiences, including childhood maltreatment, lead to neurobiological changes in frontolimbic functions that, in turn, result in altered stress and reward responses, heightened impulsivity, affect dysregulation, and, ultimately, increased risk for maladaptive behaviors such as substance use. The aim of this preliminary investigation using cross-sectional data was to test associations between these factors in the relationship between childhood maltreatment and alcohol use problems in a sample of emerging adults. Methods: Emerging adults (18–30 years old) who identified as regular drinkers (i.e., drinking at least 2–4 times in the past month) were recruited from a crowd-sourcing platform (Prolific) as well as community samples. Participants completed online standardized questionnaires assessing reward sensitivity and responsiveness, impulsivity, emotion regulation, and alcohol consequences. Results: Path analyses demonstrated good fit for the data (SRMR = 0.057, RMSEA = 0.096, 90% CI [0.055, 0.142], CFI = 0.957). Childhood maltreatment was associated with reward responsiveness (β = −0.026, Z = −4.222, p &lt; 0.001) and emotion dysregulation (β = 0.669, Z = 9.633, p &lt; 0.001), which in turn was associated with urgency and, subsequently, alcohol consequences (β = 0.758, Z = 7.870, p &lt; 0.001). Conclusions: Although these findings are preliminary, the current study is one of the first to test a comprehensive model addressing the relationship between childhood maltreatment and alcohol use problems. The findings have the potential to inform treatment strategies that target motivation and goal-directed action for reducing and managing consequences associated with childhood maltreatment. Future research should test the model using longitudinal data to address the limitations of a cross-sectional study and assess temporal associations between constructs.

"Understanding The Impact Of Childhood Sexual Abuse And Child Maltreatment On Non-Suicidal Self-Harm: The Mediating Role Of Self-Blame In Young Adults Of Pakistan"

"Understanding The Impact Of Childhood Sexual Abuse And Child Maltreatment On Non-Suicidal Self-Harm: The Mediating Role Of Self-Blame In Young Adults Of Pakistan"

Defining child maltreatment for research and surveillance: a Delphi study in 34 countries

Abstract Background Child maltreatment is a complex public health issue that has consequences across the life-course. Studies to measure child maltreatment and identify interventions and services are constrained by a lack of uniform definitions across sectors and countries. We conducted a Delphi study to reach consensus on types and characteristics of child maltreatment for use in surveillance and research in Europe. Methods Statements were developed following a scoping review and identification of key concepts by an international expert team (n = 19). A multidisciplinary expert panel (n = 70) from 34 countries participated in three rounds of online data collection. We defined consensus as ≥ 70% agreement or disagreement with each statement after the final round. Results Consensus was reached on 26/31 statements, with a participant retention rate of 94%. The definition states that child maltreatment is a subtype of violence against children. The perpetrator can be an adult or minor, but must be in a position of power over the child. To define an act or omission as child maltreatment, it must cause harm or have the potential to cause harm, regardless of intention, severity, chronicity, or the traditional/cultural beliefs of the perpetrator. In addition, the broad umbrella term encompassing emotional, behavioural or cognitive maltreatment should be “psychological”, and psychological maltreatment should be split into sub-types of psychological abuse and psychological neglect. “Neglect” is a broad type of child maltreatment within which there are subtypes that can all be characterised as “failure to provide” or “failure to supervise”. Conclusions This is the first study to demonstrate consensus on the types and key characteristics of child maltreatment across multiple sectors and countries, providing a unified definition of child maltreatment to improve consistency of measurement and surveillance in Europe. This abstract is submitted on behalf of Working Group 1 COST Action 19106. Key messages • A standardised definition is essential for monitoring child maltreatment. • We propose a consensus-based definition that can be used to improve child maltreatment measurement in research and surveillance.

Common neural correlates of disgust processing in childhood maltreatment and peer victimisation.

Childhood maltreatment and peer victimisation are common sources of early-life interpersonal stress. Childhood maltreatment is associated with atypical frontolimbic emotion processing and regulation, and increased vulnerability for self-harm/suicide. However, few studies have compared the neurofunctional correlates between caregiver- versus peer-inflicted mistreatment. We compared the alterations of neurofunctional correlates of facial emotion processing in youths exposed to childhood maltreatment or peer victimisation, and explored their associations with self-harm. Functional magnetic resonance imaging data were collected from 114 age- and gender-matched youths (39 childhood maltreatment, 37 peer victimisation and 38 controls) during an emotion discrimination task. Region-of-interest (amygdala, insula) and whole-brain analyses were conducted. Groups differed significantly during disgust processing only. Both groups had lower activation in the right amygdala and bilateral posterior insula than controls; left insular underactivation was furthermore related to increased self-harm in maltreated youths. Compared with controls, at the whole-brain level, both groups also had underactivation in a cluster of bilateral limbic-thalamic-striatal, precuneus/posterior cingulate, temporal, fusiform/lingual and cerebellar regions, which was negatively associated with emotional problems in controls, as well as a cluster of somatosensory regions associated with increased self-harm in maltreated youths. Early-life interpersonal stress from caregivers or peers is associated with common underactivation of limbic-thalamic-striatal, precuneus/posterior cingulate and somatosensory regions during disgust processing. The hypoactivation of key emotion and sensory processing and self-referential brain regions could be a potential suppressive mechanism to cope with the aversive emotion; however, it may also entail increased risk of affective psychopathology in seemingly healthy youths.

Prediction of depressive symptoms in young adults by polygenic score and childhood maltreatment: Results from a population-based birth cohort.

Childhood maltreatment is linked with later depressive symptoms, but not every maltreated child will experience symptoms later in life. Therefore, we investigate whether genetic predisposition for depression (i.e., polygenic score for depression, PGSDEP) modifies the association between maltreatment and depressive symptoms, while accounting for different types of maltreatment and whether it was evaluated through prospective and retrospective reports. The sample included 541-617 participants from the Quebec Longitudinal Study of Child Development with information on maltreatment, including threat, deprivation, assessed prospectively (5 months-17 years) and retrospectively (reported at 23 years), PGSDEP and self-reported depressive symptoms (20-23 years). Using hierarchical linear regressions, we found that retrospective, but not prospective indicators of maltreatment (threat/deprivation/cumulative) were associated with later depressive symptoms, above and beyond the PGSDEP. Our findings also show the presence of gene-environment interactions, whereby the association between maltreatment (retrospective cumulative maltreatment/threat, prospective deprivation) and depression was strengthened among youth with higher PGSDEP scores. Consistent with the Diathesis-Stress hypothesis, our findings suggest that a genetic predisposition for depression may exacerbate the putative impact of maltreatment on later depressive symptoms, especially when maltreatment is retrospective. Understanding the gene-environment interplay emerging in the context of maltreatment has the potential to guide prevention efforts.

Child maltreatment and executive function development throughout adolescence and into young adulthood.

Child maltreatment impacts approximately one in seven children in the United States, leading to adverse outcomes throughout life. Adolescence is a time period critical for the development of executive function, but there is little research examining how abuse and neglect may differently affect the developmental trajectories of executive function throughout adolescence and into young adulthood. In the current study, 167 adolescents participated at six time points from ages 14 to 20. At each time point, adolescents completed behavioral tasks measuring the three dimensions of executive function (working memory, inhibitory control, and cognitive flexibility). Neglect and abuse in early life (ages 1-13) were reported at ages 18-19. Unconditional growth curve models revealed age-related improvement in all three executive function dimensions. Conditional growth curve models tested the prospective effects of recalled neglect and abuse on the developmental trajectories of executive function. The results revealed that neglect was associated with developmental changes in working memory abilities, such that greater levels of neglect during ages 1-13 were associated with slower increases in working memory abilities across ages 14-20. These findings highlight the adverse consequences of early neglect experiences shown by delayed working memory development during adolescence into young adulthood.

The use of technology and mobile health apps in child maltreatment interventions: Perspectives of TF-CBT therapists and SafeCare providers

BackgroundPrevious research has demonstrated positive effects of using technology as an augmentation to evidence-based youth mental health treatment and parenting programs, however, limited research has examined the use of technology in evidence-based child maltreatment (CM) prevention and treatment. ObjectivesThe purpose of this paper is twofold: 1) to understand the application of technology and mobile health apps in CM prevention and treatment programs and 2) examine the acceptability of CM programs with an evidence-informed app, JoyPop™, developed to promote resilience through emotion regulation. Participants and SettingTrauma-Focused Cognitive Behavioral Therapy (TF-CBT) therapists (N = 12) and SafeCare© providers (N = 12) were recruited and participated in virtual semi-structured interviews. MethodParticipants tested the JoyPop™ app over one week and were interviewed to assess their perspectives about and experiences using technology and mobile health apps in practice (aim 1) and the potential use of JoyPop™ as a program augmentation (aim 2). Data collection and analysis was guided by qualitative descriptive analysis. ResultsParticipants reported that technology and apps supporting positive coping strategies, including JoyPop™, are relevant to the goals of CM programs and can be used enhance client engagement and skill uptake. Participants noted that JoyPop™'s features more strongly align with the components of TF-CBT than Safecare. Limitations of technology use in practice are discussed. ConclusionsSupplementing CM programs with technology and mobile health apps may be used to bolster client engagement and positive outcomes. Future research is needed to address the efficacy and client acceptance of technology and app usage in practice.

Evaluating bias of child maltreatment referrals in encounters for unintentional ingestions

BackgroundUnintentional ingestions commonly result in presentation to the pediatric emergency department (PED). No standardized recommendations exist regarding when to call Child Protective Services (CPS) for unintentional ingestions, which allows for the possibility of biased decision-making. ObjectiveIdentify patient and visit level characteristics associated with CPS referral status in unintentional ingestion encounters. Participants and SettingRetrospective cross-sectional study of children ≤6 years old presenting with unintentional ingestion to a metropolitan PED from 2015 to 2021. MethodsICD-10-CM codes were used to identify unintentional ingestion visits in the electronic health record. CPS referral was determined by manual chart review. Bivariable and multivariable logistic regression models identified patient and visit level characteristics associated with CPS referral. Socioeconomic status (SES) was classified based on zip code, the Child Opportunity Index data, and insurance. ResultsOf 3,836 charts reviewed, 808 met inclusion criteria. CPS referrals were made in 109 (13.5%) visits. Compared to non-Hispanic white patients, non-Hispanic Black patients had 7.37 (95% CI:1.38, 39.26) higher adjusted odds of being referred to CPS after adjusting for triage level, age, and ingestion type. Patients in the Lowest SES group had a 3.01 (95% CI:1.42, 6.40) higher adjusted odds when compared to the Middle/Highest SES group. ConclusionThis study found that CPS referrals in unintentional ingestions occur more often in those identifying as non-Hispanic Black and in those in the Lowest SES group, suggesting clinician bias may impact the decision regarding referrals. To mitigate subjective decision-making, we propose creating standardized, objective CPS referral criteria for unintentional ingestions.

The Long-Term Consequences of Family Violence Victimization: An Umbrella Review of Longitudinal Meta-Analyses on Child Maltreatment and Intimate Partner Violence

The Long-Term Consequences of Family Violence Victimization: An Umbrella Review of Longitudinal Meta-Analyses on Child Maltreatment and Intimate Partner Violence

Patterns of Adolescent Peer Affiliation among Youth At-Risk of Maltreatment

This study examined patterns of peer affiliations and their associations with child maltreatment, substance use, and future expectations. This study focused on 844 adolescents from the Longitudinal Studies of Child Abuse and Neglect. We identified four distinct peer-affiliation patterns: (1) no affiliation with peers who engage in either prosocial or deviant behaviors; (2) affiliation with peers using substances; (3) affiliation with peers who engage in severe deviant behaviors; and (4) affiliation with peers who engage in prosocial behaviors. Youth with sexual abuse experiences were more likely to be affiliated with peers who engage in severe deviant or prosocial behaviors. We also found different substance use and future expectations depending on peer affiliations. This study highlights the importance of examining both prosocial and deviant peer affiliations.

The mediation role of gray matter volume in the relationship between childhood maltreatment and psychological resilience in adolescents with first-episode major depressive disorder

Previous studies have revealed morphologic alterations in patients with major depressive disorder (MDD) with experiences of childhood trauma. However, the underlying neural mechanisms remain largely unknown. This study aims to explore the brain structural changes and their possible mediation role in the relationship between childhood maltreatment and psychological resilience in drug-naïve adolescents with first-episode MDD. A total of 57 adolescents with first-episode MDD and 36 healthy controls (HCs) completed the T1-weighted magnetic resonance imaging scan. The adverse childhood experiences and current psychological resilience were assessed using the Childhood Trauma Questionnaire-Short Form and the Connor Davidson Resilience Scale, respectively. The voxel-based morphometry approach was applied to examine changes in the gray matter volume (GMV). Compared with the HCs, adolescents with MDD had significantly reduced GMV volumes in the left fusiform gyrus, right orbitofrontal gyrus, right superior temporal gyrus, right calcarine cortex, right middle frontal gyrus, left angular gyrus, right precuneus, right posterior cingulate gyrus, and right posterior central gyrus, as well as significantly increased GMV volumes in the left lenticular putamen and right lenticular pallidum. The GMV of the right calcarine cortex was found to be negatively correlated with the severity of emotional abuse and positively correlated with the level of psychological resilience. Moreover, the GMV of the right calcarine cortex might partially mediate the relationship between childhood maltreatment and psychological resilience. The present study provided further evidence for structural impairments in adolescents with MDD. Our findings also confirmed the important role of depression-related GMV changes in childhood growth experiences and psychological resilience characteristics during adolescent brain maturation.