Background and Purpose: Parents of autistic children face caregiving challenges, yet there is a dearth of research specifically analysing parents’ autoethnographies. This systematic literature review explores themes of challenges and coping strategies in autism caregiving, guided by the Transactional Theory of Stress and Coping (Lazarus & Folkman, 1984). Methodology: Following Kitchenham and Charters’ (2007) guidelines, a systematic literature search of autoethnographies by parents of autistic children was conducted using online databases. The search was guided by two questions: (1) What are the challenges faced by parents caring for their autistic children?; and (2) What are the coping strategies employed by parents in caring for their autistic children? Findings: Twelve autoethnographies were analysed. Themes regarding challenges included parents experiencing fears, feeling despair and facing barriers and stigmatisation. Coping strategies identified included parents seeking answers, having hopes, and gaining empowerment besides providing support. Limitations and future research directions were discussed. Contributions: This paper emphasises understanding challenges faced by parents of autistic children. It illuminates emotional and societal aspects of autism parenting, emphasising the necessity for tailored support systems. Additionally, it reveals parents' coping strategies, including empowerment and supporting others, indicating increased understanding of their children's autism and active facilitation of support networks. Keywords: Well-being, Autism parenting, Autoethnography, challenges, coping. Cite as: Bakar, R. A., Ghani, K. D. A., Aziz, N. I., & Mohamad, N. H. S. (2024). Challenges and coping strategies of autism parenting: A systematic literature review of parents’ autoethnographies. Journal of Nusantara Studies, 9(2), 340-370. http://dx.doi.org/10.24200/jonus.vol9iss2pp340-370