The health care industry, a major contributor to greenhouse gas emissions and landfill waste, must focus on sustainable efforts. The American Nurses Association (ANA) Scope and Standards of Practice deems nurses accountable to achieve sustainable goals in the workplace. This article shows how the chief nursing officer (CNO) council of one health care system partnered with the organization’s sustainability department to integrate sustainability efforts into daily operations across the system. Each CNO was tasked to determine key performance indicators for their location, identify facility champions, and support sustainability efforts. Some joint initiatives included education, waste reduction and diversion, 501(c)3 donation, and device reprocessing. The health care industry, a major contributor to greenhouse gas emissions and landfill waste, must focus on sustainable efforts. The American Nurses Association (ANA) Scope and Standards of Practice deems nurses accountable to achieve sustainable goals in the workplace. This article shows how the chief nursing officer (CNO) council of one health care system partnered with the organization’s sustainability department to integrate sustainability efforts into daily operations across the system. Each CNO was tasked to determine key performance indicators for their location, identify facility champions, and support sustainability efforts. Some joint initiatives included education, waste reduction and diversion, 501(c)3 donation, and device reprocessing. Deborah C. Stamps, EdD, MBA, MS, RN, GNP, NE-BC, is system vice president at Rochester Regional Health/Quality, Safety & Innovation Institute, in Rochester, New York. She can be reached at [email protected] . Michael G. Waller, PhD, is Director of Sustainability, Special Assistant to the CEO at Rochester Regional Health. Susan M. Foley, PhD, RN, is a consultant at Rochester Regional Health, Wegman Center for Workforce Development. Jennifer Gales, MSN, RN, is Vice President, Chief Nursing Officer at Unity Hospital in Rochester. Rebecca Alley, BSN, MS, RN-B, is Chief Nursing Officer at Alexander Park Medical Group in Rochester. Cindy Lovetro, MS, BS, RN, LNHA, is Chief Nursing Officer, Long Term Care at Rochester Regional Health. Kristin Opett, BSN, RN, MSHA, is Vice President, Chief Nursing Officer at Rochester General Hospital, Rochester Regional Health. Theresa Glessner, DNP, RN, ACNP, BC, NEA-BC, CCRN, is Vice President, Chief Nursing Officer at Newark Wayne Community Hospital in Newark, New York. Sheri Faggiano, MSN, RN, is Vice President, Chief Nursing Officer at United Memorial Medical Center in Batavia, New York.