Chemistry Section Research Articles

PRODUCTION OF YELLOW WOOD ROOT TEA AS A BLOOD SUGAR STABILIZER

Diabetes mellitus is a disease or metabolic disorder that is increasing year by year, characterized by high blood sugar levels as a result of insulin function insufficiency. Diabetes mellitus, which is often referred to as diabetes, is a disease or metabolic disorder that is increasing year by year, characterized by high blood sugar levels as a result of insulin function insufficiency. Treatment is by using drugs. Currently, a treatment using herbal medicine is being developed, one of which is Kayu kuning, where in previous studies it was found that the roots of Kayu kuning can reduce blood glucose levels. This has triggered the Biochemistry and Medical Chemistry section of the Faculty of Medicine to introduce to the public the preparations of this herbal medicine with ready-to-use packaging and the right dosage. The process of making tea is carried out at the Chemical Basic Medicine Laboratory, Faculty of Medicine, Sriwijaya University. About 5.6 kg of yellow wood root, washed and cut into small pieces then dried and ground to obtain a coarse powder (simplicia) of about 2.5 kg. Yellow wood root simplicia is put into tea bags weighing 10 g per bag. One tea bag can be brewed with 200 mL of hot water and drunk once a day. In this service, 250 tea bags were produced which were packaged in 50 packages (5 tea bags/package). The production of this yellow wood root tea has been carried out in the Komplek Azhar Lama, Kenten Laut, Palembang.
 Keywords: Herbal medicine, yellow root (Arcangelisia flava)

A suggested program based on 7E Instructional Model and AWE Systems to Develop Faculty of Education ESP Students' Academic Writing Skills

The aim of the current research was to investigate the effect of a suggested program based on 7E instructional model and AWE systems on developing faculty of education ESP students' academic writing skills. The design of the present research was a pre-post experimental group. The participants of the research were thirty second year, ESP students enrolled in English Chemistry, Biology and Science sections at Faculty of Education, University of Sadat City. They were taught using the suggested program based on 7E instructional model and AWE systems. The instrument of the research was an ESP academic writing test with a rating scale for assessing the participants' academic writing skills. The test was applied to the participants of the research before implementing the suggested program to measure their level in academic writing skills. Then, it was re-applied after the implementation of the suggested program. Results of the research have revealed that second year, faculty of education ESP students' academic writing skills were developed after the implementation of the suggested program. Accordingly, the suggested program based on 7E instructional model and AWE systems was found to have a positive effect on developing faculty of education ESP students' academic writing skills.

Strategies for the integration of foundational and clinical sciences in doctor of pharmacy programs

AbstractIntroductionEnhancing the integration of foundational and pharmaceutical sciences with the clinical pharmacy curriculum will develop practitioner‐scholar pharmacists. However, implementing and assessing integration is challenging. Hindrance factors include limited pragmatic approaches, the lack of a “how‐to” blueprint, faculty and student resistance to change, compression of pharmaceutical science teaching, and a paucity of assessment strategies.MethodsThis study examined the history, theory, and practice of integration and utilization of the 2013 Center for Advancement of Pharmacy Education (CAPE) Outcomes to achieve integration in Doctor of Pharmacy (PharmD) programs. For this, 252 faculty members across the American Association of Colleges of Pharmacy (AACP) Biological Sciences, Pharmaceutics, and Chemistry sections were surveyed to assess faculty perception regarding (1) the importance of integrating foundational and clinical sciences, (2) the extent, and (3) intentionality of incorporation of the 2013 CAPE Outcomes in the foundational sciences. The 2013 CAPE Outcomes perceived to be challenging to incorporate into the foundational sciences were identified. Subsequently, strategies for integration and assessment grounded in educational theories were developed.ResultsPatient advocacy (CAPE 3.3), cultural sensitivity (CAPE 3.5), innovation and entrepreneurship (CAPE 4.3), medication use management (CAPE 2.2), self‐awareness (CAPE 4.1), and leadership (CAPE 4.2) received scores suggesting limited incorporation in foundational sciences. To address this, examples of integration strategies were shown based on these 2013 CAPE Outcomes to enhance foundational science bridging with clinical and practice pharmacy education. Curricular models such as the McMaster method, H and Z stack approaches, and the Harden's Ladder as an assessment tool to measure curricular integration are examined in the context of the 2013 CAPE Outcomes, grounded in educational theory.ConclusionThis work summarizes the recommendations of the AACP Biological Sciences Section Task Force for examples of methods for achieving, augmenting, and assessing the integration of pharmaceutical and foundational sciences with clinical practice in PharmD programs.

Immersive VR for Organic Chemistry: Impacts on Performance and Grades for First-Generation and Continuing-Generation University Students

Rapid advances in the quality and accessibility of immersive virtual reality (IVR) have brought about intense interest in applications of the technology within higher education, including STEM (science, technology, engineering, mathematics) teaching and learning. However, evidence is mixed on the effectiveness of IVR for STEM teaching and learning, and there are currently few models of how best to incorporate these activities into typical STEM courses. We created a sequence of IVR activities for teaching concepts in organic chemistry and carried out an experimental investigation on the impacts of these on student performance, with special focus on student characteristics including first-generation college student status, gender, and ethnicity. Two sections of Organic Chemistry were compared; in one randomly assigned section, students had the option of completing these IVR activities, and in the other, they did not. Results showed a trend towards improved course grades and final exam scores in the section offered IVR activities, particularly for first-generation college students. These findings suggest that IVR can be a practical and effective way to reinforce learning and student success in realistic university STEM settings, especially for certain demographic subgroups.

Measuring supports from learning assistants that promote engagement in active learning: evaluating a novel social support instrument

BackgroundActive learning supports student performance, but can be challenging to implement in large courses. The Learning Assistant (LA) Program is a growing intervention to support students in large active learning classrooms. This program places advanced undergraduates who have training in pedagogical methods in active learning classrooms to interact with and support students during in-class activities. LAs increase student performance, but the mechanism behind this is still unclear. Social support is a promising framework to help elucidate the types and extent of assistance LAs provide to students and begin exploring the “how” behind LAs effectiveness. The aim of this study was to develop an instrument measuring undergraduate students’ perceptions of the social supports for active learning available to them in the classroom. This instrument was based on both the broader social support literature and the literature on what factors encourage students to engage deeply in active learning. To provide initial evidence of validity, the instrument was completed in six sections of General Chemistry I at one R1 university. Exploratory and confirmatory factor analyses were applied to determine the internal structure of the instrument. Then the instrument’s relationship to engagement in active learning was evaluated as another form of validity evidence.ResultsThese analyses best supported a three-factor instrument that included five items representing supportive feedback provided during active learning (appraisal support), eight items representing emotional support during active learning, and six items representing the communications of norms and values related to active learning (informational support). All three factors were individually correlated with three measures of engagement. In regression analyses with all three factors measured together, only informational support predicted changes in two of the three measures of engagement.ConclusionsThis study supports the use of the Perception of Social Supports for Active Learning (PSSALI) instrument to understand students’ perceptions of the supports they are receiving to engage in active learning in chemistry courses. One implication of this work is that in order to increase engagement, learning assistants should clearly communicate the value of active learning and the classroom norm of active participation.

10th Anniversary of Applied Sciences-Invited Papers in Chemistry Section

MDPI´s Applied Sciences reached a remarkable milestone in 2020 when the 10th volume of the journal was published and an impact factor of 2 [...]

Implementation and evaluation of an adaptive online summer preparatory course for general chemistry: Whom does it benefit?

General chemistry courses are key gateways for many Science, Technology, Engineering, and Mathematics (STEM) majors. Here, we report on the implementation and evaluation of an adaptive, ALEKS-based online preparatory module (PM) for general chemistry. The module was made available in Summer 2018 at no cost to all students entering any section of general chemistry that fall. Of the 827 students who registered into the PM, 44% fully completed the module, 48% completed part of the module, and 8% did not complete any of the module. Considering students enrolled in first-term general chemistry, we find a marked increase in ACS final exam percentile for students who completed more than 50% of the module. This is suggested to reflect the self-selection of users who were highly motivated and/or likely to succeed in the course, a hypothesis supported by an analysis using an internal diagnostic metric, the predicted first-year quality point average (PQPA). To examine longer term impacts of the PM, we examined performance in subsequent chemistry courses, through second-semester organic, and found that students completing more than 50% of the module outperformed their counterparts across all courses, with the gap largest in first semester general chemistry and narrowing across subsequent courses. Finally, we surveyed students in summer 2020, two years after the PM offering. The survey indicated overall satisfaction with the PM. For students who did not complete the module, primary reasons given were difficulty (29% of respondents) and insufficient time (46%). As the module did not proportionally benefit the target group of underprepared or at-risk students, we suggest tweaks for future implementations.

Nutritional and Physico-Chemical Evaluation of Four Different Packed Mango Juice Samples

Aim: To analyze mango fruit juice samples for their nutritional value. Mango fruit is perishable in nature and cannot be stored for long time. It can be made available during off season, by processing in to juices, jams, squashes, nectars, chutney, pickles, toffees and canned mango slices etc.
 Study Design: Different physico chemical and elemental parameters were studied for four different made tetra packed mango juice samples available in local market.
 Place and Duration of Study: Department of Applied Sciences, Chemistry section, University of Technology and Applied Sciences, Muscat, Oman. The study was performed during the January 2016 – July 2016.
 Methodology: Different parameters were studied such as pH, conductivity, acidity, ash content, vitamin C, moisture and some mineral contents. Some chemical and instrumental methods were used for analysis. 
 Results: pH was found to be in the range of 3.17 – 3.97, conductivity 0.941 – 1.053 MS/cm, sugar found in the range of 13 – 15 0brix, density was found 0.939 – 1.015 g/cm3, water 65.25 – 67%, ash was found to be in the range of 0.059 – 0.099%, total acidity found 0.173 – 0.275 %. Vitamin C was found in the range of 24.8 – 67.3 mg/100 ml, potassium 6.6 – 94, sodium 6 – 69 mg/100 ml, calcium 0 – 105 mg/100 ml and iron was found to be in the range of 1.375 – 2.145 mg/100 ml.
 Conclusion: Based upon result obtained found that content of all selected samples were contains labelled nutrients. Sample STMJ was having remarkable good amount of Vitamin C while sample ARMJ found good amount of potassium and iron content. In acidic perspective sample PMJ was higher acidic and ARMJ sample less acidic in nature.

Physico-Chemical Analysis of Various Samples of Tomato Ketchup

Aim of our present study was to analyze physico-chemical properties of tomato ketchup samples available in the local market. Major part of tomato consumption comes under processed products like tomato juice, ketchup and sauce. Recent studies have indicated the potential health benefits of a diet that are rich in tomatoes. Study of various physico-chemical parameter testing of four different types of tomato ketchup samples. Study was performed in Department of Applied Sciences, Chemistry section, University of Technology and Applied Sciences, Muscat, Oman during the September 2017 – April 2018. 
 We have selected four different tomato ketchup samples from the local brand and tested for their various physical and chemical parameters such as, pH, conductivity, viscosity, solubility, acidity total, moisture, ash, vitamin C, sodium, potassium, calcium and magnesium. We have used routine and simple techniques for analysis. Such as some chemical methods, Flame photometer etc. We have found that, pH was in the range of 3.6 – 3.8, conductivity 5.38 – 8.71 MS/cm, viscosity 3.93 – 6.76 Pa s, solubility 53.35 – 61.12, titratable acidity 3.2 – 4.01 g/100 gm, (pH metric 3.6 – 4.3 g/100 gm), ash 1.62 – 2.98%, vitamin C 17.25 – 55.23 mg/100 gm, sodium 294.5 – 475.85 ppm, potassium 93.5 – 153.3 ppm, magnesium 106 – 163 ppm, calcium 67 – 117 ppm. The result found in our analysis was more or less close to each other. On the basis of result obtained during the analysis of four tomato ketchup samples Jumbo sample was good amount of vitamin C, less ash value lowest sodium content.

Can electrochemistry help to understand superconductivity – β-Fe1+Se as a case study

Superconductivity is a riddling phenomenon. Even after more than a century of research, the mechanism that drives the so-called ‘unconventional’ superconductors has not been fully understood. Although the phenomenon is closely linked to low-temperature research which is usually not the preferred condition for an electrochemist, the structures itself determining the superconducting behaviour are synthesised, studied and modified at much higher temperatures. Electrochemistry provides an unmatched lever to change the thermodynamic ground state and to modify or synthesise compounds. Concomitantly, it affords a precision for the investigation of compositions superior to other chemical methods. In this review, the example of the iron-based superconductor β -Fe 1+ x Se is chosen to evaluate achievements and prospects of this research at the cross section of (electro)chemistry and (solid state) physics.

Evaluation of Nutritional Fact and Study of Various Physico-chemical Parameters of Black, Green and Red Grapes Samples in the Local Fruit Market

Aims: Aim of our study was to analyze various nutritional fact of three types of grape fruits and compare their facts in terms of consumption. The grape is one of the most edible fruit with high amount of nutritional and medicinal properties.
 Study Design: Physico-chemical analysis by using various chemical analysis and instrumental methods for analysis of various grape samples.
 Place and Duration of Study: Department of Applied Sciences, Chemistry section, University of Technology and Applied Sciences, Muscat, Oman. The study was performed during the May 2018 – December 2018.
 Methodology: We have selected three different grapes samples from the local market for the analysis (Green grapes, Red grapes and Black grapes). Our research study includes testing of various physico-chemical parameters for nutritional fact of fruit, such as water, carbohydrates, proteins, fat, vitamin C, and different minerals. We analyzed various physic-chemical parameters.
 Results: We found that pH in the range of 3.775 – 4.14, conductivity 1.39 MS/cm – 1.553 MS/cm, titratable acidity was measured in terms of tartaric acid was found 0.712 g/100ml - 1.065 g/100ml and Brix% value 9.5% - 15.5%. Amount of water in berry was 77.964 % – 80.146 %, Ash in the range of 0.72 – 3.911 %. Protein 6.245 g/100ml – 7.928 g/100ml, Fiber content 1.112 % – 1.143% and good amount of potassium, magnesium, calcium, iron and zinc. 
 Conclusion: Analysis of three types of grapes we found, acidity of green grapes was highest. It might be depending upon ripening stage of berry. That are correlated to sugar (0Brix). Fiber value was very close to each other. Iron was highest in red grapes and then green grapes. Potassium, magnesium, calcium and zinc was found to higher in green grapes. Based on this green grape looks batter nutritional value.

Dynamics of Organic Residue Decomposition and Mineralization of Nutrients in Soil

The present study was undertaken to investigate “Dynamics of Organic Residue Decomposition and Mineralization of Nutrients in Soil” during the year 2018-19 at Soil Science and Agricultural Chemistry Section, College of Agriculture, Nagpur. The experiment was laid out in completely randomized design (CRD) with nine treatments replicated thrice. The treatments were absolute control in T1, cowdung mixture in T2, paddy straw in T3, wheat straw in T4, sugarcane trash in T5, gliricidia lopping in T6, subabul leaves in T7, soybean stalks in T8, greengram stalks in T9. Subabul leaves mixture (T7) recorded maximum ammoniacal nitrogen and nitrate nitrogen throughout experimentation. Gliricidia lopping mixture ranked 1st by recording maximum P mineralization for 30, 60 (7.33 mg kg-1), 90 (7.55 mg kg-1) and 120 (7.45 mg kg-1) days of experimentation. Sulphur mineralization was also found highest in T6 by application of gliricidia lopping mixture during experimentation. Hence, for fast decomposition and nutrient mineralization legume residue is more efficient than cereal or other organic residue.

Adapting to the COVID-19 Online Transition: Reflections in a General Chemistry Sequence Taught by Multiple Instructors with Diverse Pedagogies

Georgia Gwinnett College (GGC) is an open-access, four-year, public liberal arts college that emphasizes excellent instruction through active learning and small class sizes. The COVID-19 pandemic presented unique challenges to GGC general chemistry instructors as they sought to actively engage students in a new online setting. We reflect on the challenges faced by our college during this pandemic by analyzing student surveys, instructor reflections, and grade distributions across 20 sections of general chemistry 1 and 2 taught by 15 different instructors. We consider the most important challenges faced by students and the technology rapidly adopted by instructors. We then present three main themes found in the instructor reflections and consider the implications for going forward.

An Overview of the Laboratory's Role in the Diagnosis and Treatment of Thrombotic Thrombocytopenic Purpura

Thrombotic thrombocytopenic purpura (TTP) is a multi-faceted disease for a clinical laboratory with diagnosis data and treatment spread across many different laboratory sections. Encompassing results from hematology, chemistry, molecular, and coagulation sections with treatment from the transfusion medicine/Blood Bank section of the laboratory, clinicians are able to accurately diagnosis and treat TTP.

Impact of COVID-19 on laboratory professionals-A descriptive cross sectional survey at a clinical chemistry laboratory in a developing country

BackgroundThe lab professionals at one end are at increased risk of contracting the infection while on the other end have to deal with the various challenges during the Coronavirus Disease 2019 (COVID-19) outbreak. This survey was undertaken to analyze the lab professionals' perspectives, in terms of the challenges, financial implications, fears, motivation and satisfaction from organizational processes and policies adopted, amid the COVID-19 crisis. Material & methodsThe study utilized a cross-sectional survey design. The survey was administered online via the google docs survey tool from medical laboratory professionals (n = 64) serving at the section of Clinical Chemistry, department of Pathology and Laboratory Medicine, the Aga Khan University (AKU), Pakistan from June 4th to 14th 2020. A team consisting of three Clinical Chemistry consultants serving as faculty at the section, designed the survey questionnaire. The responses were recorded on a five-point Likert Scale (1 = strongly disagree, 2 = disagree, 3 = neutral, 4 = agree and 5 = strongly agree). The statistical analysis was performed using the Microsoft Excel 2013. Frequency and percentages were calculated for gender, experience and designation while descriptive results based on the responses were also recorded. ResultsThe response rate was 78% (n = 50). 60% responded that the current lifestyle adopted during the pandemic was not better than the traditional one. The fear of employment termination and financial challenges were being faced by 42% and 78% respondents respectively. The quality of family life was improved in 54% cases while 96% were of the view that their social activities at work have suffered. Whereas, 22% were not satisfied by the measures taking by the management during the outbreak. ConclusionThe findings of this survey provide laboratorians' perspective, in times of such crisis and provides us certain lessons to prepare for such unpredicted situations in future.

Influence of organic residue addition on CO2 evolution and N mineralization in soil

A combination of pot culture experiment and incubation study was conducted at the soil science and agricultural chemistry section, college of agriculture, nagpur to assess the decomposition potential and rate of mineralization of nitrogen of different organic residues. Initially, the rate of CO2 evolution was near constant during 10 days of incubation peaking on 3rd day after incubation. There was a steep increase in CO2 evolution in all the treatments after 10 days, attaining its peak at 70 days after incubation thereafter it began to decrease in a non-uniform pattern upto 120 days. Cummulatively, maximum CO2 evolution was recorded in green gram stalks followed by sugarcane trash and lowest was found in control pot. Nitrogen mineralization in pot culture experiment was analysed at 4 monthly intervals viz. 30, 60, 90 and 120 days. There was a sharp increase in the rate of N mineralization at 60 days interval and altogether, there was a decreasing trend of nitrogen mineralization after 60 days of experimentation. The peak amount of mineralization was observed at 90 days in near about all the treatments. Subabul leaves mixture (T7) recorded maximum ammoniacal nitrogen (48.98 mg kg-1, 52.66 mg kg-1, 56.99 mg kg-1 and 44.99 mg kg-1) and nitrate nitrogen (26.25 mg kg-1, 38.02 mg kg-1, 30.01 mg kg-1 and 20.83 mg kg-1) throughout the experimentation. The results highly indicated that addition of all residues produced a significant increase in soil organic carbon and nitrogen but, leguminous residues showed a higher response.

Automation and Molecular Diagnostics: A New Era in Clinical Microbiology

The environment of the clinical microbiology laboratory is rapidly changing. Testing methodologies based upon organism growth on an array of liquid and solid media are being replaced by newer methods that enhance the rate of organism identification as well as increase the sensitivity and specificity by which identification occurs. A majority of these new techniques are based upon nucleic hybridization and polymerase-chain reaction technology and range from identification of single-organisms or organism families to multiplexed syndromic panels, which can concurrently examine for the presence of numerous suspect organisms based upon the symptoms exhibited by the patient. In addition, the clinical microbiology laboratory now has access to a level of automation thus far only seen in the chemistry and hematology sections of the clinical laboratory. These transitions have been repeatedly shown to enhance the level of patient care when properly implemented into the laboratory workflow. Conversely, with the rapid encroachment of these new technologies comes potential downfalls, including cost and challenges with training laboratory staff. Collectively, the clinical microbiology laboratory is coming into a new era of technology and patient care that will bring about dramatic changes to conventional testing and organism identification.

Контекстні хімічні завдання як засіб реалізації інтегрованої підготовки майбутніх вчителів природознавчих дисциплін

The article depicts didactic and functional possibilities of contextual tasks while teaching Chemical studies (on the example of organic and inorganic Chemistry), it also demonstrates the role of forming integrated natural competences of future Nature Studies teachers. The concept of contextual approach is directed on the necessity of gaining new knowledge and its further application for improving the preparation of future Nature Studies teachers. The usage of contextual tasks provides all- round development of students, readiness to the independent work and increasing the professional level of future specialists. Contextual tasks enrich the traditional contest of Natural studies in pedagogical establishments of higher education by using the tasks directed to the application of the knowledge in situations which are close to future professional activity. Besides, the application of contextual tasks of different levels with the usage of different sections of Chemistry gives the objective evaluation of the student competence in the subject. The article discloses the concept of the notion «contextual task», observes the principles of its designing, it proves the meaning of the tasks of the similar types, role and placement of the contextual tasks in forming professional competence of future specialists while preparing teachers of Nature disciplines (Chemistry, Physics, and Biology). The main stages of constructing textual tasks are depicted. The authors distinguish the following types of contextual tasks in general and inorganic chemistry: subjective tasks (the conditions of these tasks are subjective problematic situation), interdisciplinary tasks (the conditions of such tasks reveal connections of Chemistry with other disciplines), practical (the condition contains the problematic situation and to solve it the students have to apply knowledgein different subjects and those gainedin practice, in everyday experience etc.) The article demonstrates some examples of different types of contextual tasks. To the authors’ mind contextual tasks as a mean of integration of the contest of substantive fields of natural-scientific disciplines give students the opportunity to get interdisciplinary knowledge concerning their future professional activity, form cultural and professional competence in Chemistry, Physics, Biology according to new educational standards.

Integrated impact of soil applied nitrogen and foliar applied micronutrients mixture (Gillette) on growth and yield of safflower (Carthamus tinctorius L.) under field conditions

Integrated soil nitrogen and foliar application of trace elements could increase crop growth and yield and decrease environmental pollution. In order to explore the impact of soil applied nitrogen and foliar applied micronutrients on safflower growth and yield, a field experiment was conducted at Soil Chemistry Section, Agriculture Research Institute, Tandojam, during Rabi season in 2016-17.Seven treatments and three replicates were used for each treatment. T1 (control), T2, T3 and T4, T5, T6 and T7 = 50, 100 and 150 kg N ha-1 (soil) + 1250 ml and 2000 ml ha-1 (foliar) were used respectively. The present study revealed that the crop was treated with N @ 150 kg ha-1 (soil) + Gillette (Micronutrients mixture) @ 2000 ml ha-1 (foliar) produced maximum plant population (42.2 m-2), plant height (126.2 cm), branches plant-1 (11.0), seeds capitulum-1 (42.9), seed index (1000 seed weight, 44.0 g) and seed yield (2400 kg ha-1) as compared to N @ 100 kg ha-1 (soil) + Gillette(Micronutrients mixture) @ 2000 ml ha-1 (Foliar) which was recorded plant population (41.1 m-2), plant height (124.8 cm), branches plant-1 (10.0), seeds capitulum-1 (41.9), seed index (43.0 g), and seed yield (2350 kg ha-1). While the lowest results for all parameters were recorded in control. It is obvious from the results that N @ 100 kg ha-1 (soil) + Gillette (Micronutrients mixture) @ 2000 ml ha-1 (Foliar) recorded optimum results due to medium dose of nitrogen and non-significant differences (LSD@5%) with T7 and T4 where highest dose of nitrogen was applied. Keywords: Foliar application; Growth; Micronutrients mixture; Safflower http://dx.doi.org/10.19045/bspab.2019.80166

The 12th AFMC International Medicinal Chemistry Symposium (AIMECS 2019) in Istanbul, Turkey.

AFMC-AIMECS meetings are internationally organized biannually by the Asian Federation for Medicinal Chemistry (AFMC) and are focused on recent studies in drug discovery and development both in academia and industry. Member organizations of the AFMC are the Pharmaceutical Society of Japan, the Chinese Pharmaceutical Association, the Royal Australian Chemical Institute, the Pharmaceutical Society of Korea, the Korean Chemical Society, the Chemical Society Located in Taipei, the Indonesian Society of Medicinal Chemistry, the Medicinal Chemistry Section of the Israel Chemical Society, and the Computer-Aided Drug Design & Development Society in Turkey. Each time, the symposium is organized within these member countries. The AIMECS 2019 symposium was held in Turkey this year, as Prof. Dr. Esin Aki-Yalcin is the current president of the AFMC (2018-2020); the next AIMECS meeting will be organized in 2021 in Tokyo, Japan. In this report, we discuss key topics at the 12th AFMC International Medicinal Chemistry Symposium - New Avenues for Design and Development of Translational Medicine (AIMECS 2019) held in Istanbul, September 8-11, 2019.