Chemistry Of Tissues Research Articles

Relation of epithelial ion transport to corneal thickness and hydration.

THE control of corneal thickness is a complex process involving the chemistry of the stromal tissue and the barrier properties of the two bounding membranes. Fluid dynamics are intimately involved, for corneal thickness is linearly related to hydration1, which in turn is affected by ion transport. Also, it was shown recently that in the rabbit cornea the epithelium is the source of an active sodium transport system, and the endothelium shows only a passive behaviour in relation to the passage of ions2.

The Clinical Chemistry and Pathologic Physiology of Thyroid Tissue

Abstract Familial goiter with hypothyroidism can be subdivided into at least 8 groups and each appears to result from an inherited disorder at a specific stage in thyroid hormone synthesis, mobilization, or peripheral effect. At times, the intense hyperplasia which accompanies one of these disorders evolves into malignant disease. Criteria for diagnosis of each are presented.

Collagen, Hexosamine and Tensile Strength of Rabbit Skin During Aging

The process of aging is accompanied by changes in the chemistry of connective tissue. As a general rule collagen seems to accumulate with increasing age. Analysis of this material on the basis of its solubility indicates that what is being accumulated is insoluble fibrous material, whereas the soluble collagens, present in significant amounts in young skin, drop to low values in older age. These observations have been reviewed in detail by Harkness (1).

Studies of the human thyroid in some pathological conditions

A change was found in the level of mucopolysaccharides, sialic acids, nucleic acids and collagen in accordance with the structural peculiarities of the thyroid in different pathological conditions of the gland. Marked shifts in the level of the above components, increasing with age, can be noted in the blood and tissues already at early stages of thyroid affection. From the structural elements of the cell, mitochondria and microsomes and also hyaloplasm are involved in the process. In the colloid of the thyroids of normal humans sulphated acid mucopoly-saccharides were identified; their level increases with age and in various pathological processes in the gland, while a decrease of the galactosamine-containing mucopoly-saccharides was noted in the blood. It was demonstrated that the so-called “euthyroid” form of goitre is a grave pathological disorder which is accompanied by a change in the chemistry of the thyroid tissue.

The syndrome of congenital adrenal unresponsiveness to ACTH in 5 patients

Because of the demonstration of human growth hormone-like activity by prolactin in the treatment of hypopituitary dwarfs (McGarry and Beck: Lancet 2: 915, 1962) we have been interested in comparing the effects of prolactin and growth hormone upon the chemistry of the connective tissue. The skins of large numbers of rats which had received either hormone were sequentially extracted in the cold with 0.15M NaC1, 0.5M NaC1, and 0.5M citrate buffer to remove quantitatively the ground substance, salt, and acid extractable collagens, respectively. The results indicate that while growth hormone was without profound effect upon the dermal chemistry of rats, prolactin administration resulted in an increase in the dermal concentration of the citrate extractable collagen (250 per cent) and marked losses of ground substance (40 per cent) , salt extractable collagen (50 per cent) , and insoluble collagen (28 per cent) from the skin. The apparent mechanism of the catabolic effect of prolactin upon dermal collagen was found to consist of three steps: (1) the release of a cytoplasmic protease into the extraeellular compartment of the skin, (2) the proteolytie activation of the collagenase-ogen found in this compar tment by the protease, and (3) the enzymatic digestion of insoluble collagen into two components, one diffusable, the other extractable in citrate buffer. This released protease also digested enzymatically the proteins of the ground substance thereby permitt ing acid mucopolysaccharides to drain away from the tissue. Thus, all the dermal chemical alterations with prolactin administration may be explained as a consequence of the release of a protease from the cells.

Changes in the Quantity and Nature of Collagen in Rabbit Skin as a Function of Age

THE process of ageing is known to be accompanied by changes in the chemistry of connective tissue. In general collagen seems to accumulate with increasing age. Nevertheless, this is only true for the insoluble fraction, since the soluble collagens, which represent the newly formed molecules, decrease with age, reflecting the lowered rate of synthesis. Most of the work in this connexion has been reviewed in detail by Harkness1.

The chemistry of connective tissue. David A. Hall, Ph.D. England, University of Leeds; Springfield, Ill., Charles C Thomas, 110 pp., 8 illustrations. Price $5.50

Arthritis & RheumatismVolume 7, Issue 3 p. 282-282 Book ReviewFree to Read The chemistry of connective tissue. David A. Hall, Ph.D. England, University of Leeds; Springfield, Ill., Charles C Thomas, 110 pp., 8 illustrations. Price $5.50 Ward Pigman Ph.D., Ward Pigman Ph.D.Search for more papers by this author Ward Pigman Ph.D., Ward Pigman Ph.D.Search for more papers by this author First published: June 1964 https://doi.org/10.1002/art.1780070311AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume7, Issue3June 1964Pages 282-282 RelatedInformation

CONNECTIVE TISSUE IX: EFFECTS OF HYPERVITAMINOSIS A UPON CONNECTIVE TISSUE CHEMISTRY.

SummaryIn general, the initial primary effect of hypervitaminosis A upon the chemistry of the connective tissue appeared to be a marked loss of hyaluronic acid and chondroitin sulfate from the saline soluble components of the tissue. With further doses of Vit. A there appeared to be a significant decrease in the glycoprotein content of these fractions. To this degree these chemical studies essentially confirm the effects of Vit. A described by others for cartilage in vitro, upon the soft connective tissues in vivo.

The chemistry of connective tissues. 8. The composition of elastin from three bovine tissues.

The chemistry of connective tissues. 8. The composition of elastin from three bovine tissues.

Book Review: The Chemistry of Connective Tissue

Book Review: The Chemistry of Connective Tissue

The Chemistry of Connective Tissue

numerous excellent illustrations, partly in color, which are well reproduced. The literature cited is extensive, with German contributions dominant. This should be of special interest to American investigators who often fail to keep up with developments abroad. The preference of German articles, understandable as it is in a text aimed primarily at a German-speaking audience, not infrequently seems to do injustice to the orginal observers, although these may get proper credit in the literature cited.

Connective tissue. IV. Effect of age upon dermal chemical response to adrenal hormones.

SummaryBoth Cortisol and Doca similarly affect the chemistry of the connective tissue in that they result in a decrease in total and insoluble collagen concentration of rat skin. The effects of these hormones upon rat skin are profoundly altered by the age of the animal. The aged rat demonstrates a considerably different dermal chemical response to Cortisol and particularly Doca than does either the young or the mature animal.

The chemistry of connective tissues. 6. The constitution of the chondroitin sulphate-protein complex in cartilage.

The chemistry of connective tissues. 6. The constitution of the chondroitin sulphate-protein complex in cartilage.

The chemistry of connective tissues. 7. Dissociation of the chondroitin sulphate–protein complex of cartilage with alkali

The chemistry of connective tissues. 7. Dissociation of the chondroitin sulphate–protein complex of cartilage with alkali

An interferometric study of the anhydrous nuclear mass of exfoliated cells from experimental cervical cancer

An interferometric study of the anhydrous nuclear mass of exfoliated cells from experimental cervical cancer

The chemistry of connective tissues. 5. The elastase activity of proteolytic enzymes.

The chemistry of connective tissues. 5. The elastase activity of proteolytic enzymes.

Ultrastructure and cellular chemistry of neural tissue

Ultrastructure and cellular chemistry of neural tissue

Ultrastructure and Cellular Chemistry of Neural Tissue. Progress in Neurobiology. II

Back to table of contents Previous article ArticleNo AccessUltrastructure and Cellular Chemistry of Neural Tissue. Progress in Neurobiology. IIDAVID NACHMANSOHNDAVID NACHMANSOHNSearch for more papers by this authorPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.115.9.864-aAboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail "Ultrastructure and Cellular Chemistry of Neural Tissue. Progress in Neurobiology. II." American Journal of Psychiatry, 115(9), pp. 864-a–864 Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited byNone Volume 115Issue 9 March 1959Pages 864-a-864 Metrics PDF download History Published online 1 April 2006 Published in print 1 March 1959

水産動物の支持組織の化学

水産動物の支持組織の化学

Ultrastructure and Cellular Chemistry of Neural Tissue

Ultrastructure and Cellular Chemistry of Neural Tissue