Division Of Chemistry Research Articles

Walking the 'design-build-test-learn' cycle: flux analysis and genetic engineering reveal the pliability of plant central metabolism.

This article is a Commentary on Morley et al. (2023), 239: 1834–1851.

Inorganic Nanoscience Award to Jonathan S. Owen

Jonathan S. Owen of Columbia University is the winner of the 2023 Inorganic Nanoscience Award. This award is presented by the American Chemical Society Division of Inorganic Chemistry to honor exceptional research in the area of inorganic nanoscience. Owen’s research is primarily focused on comprehending the interplay between nanocrystal surfaces and ligands, as well as the mechanism governing the nucleation and growth of colloidal nanocrystals. His findings have led to the development of improved synthetic pathways for nanomaterials. An award symposium featuring Owen’s work will be held at ACS Fall 2023.

Sustainability: Advances and Applications. An Introduction to Manuscripts Based on the ACS Presidential–Agricultural & Food Chemistry Division Symposium Held during the 261st ACS National Meeting in April 2021

The symposium Sustainability: Advances and Applications was held during the virtual 261st ACS National Meeting, April 2021. The symposium was co-organized by 2021 ACS President H. N. Cheng and the Agricultural and Food Chemistry Division of ACS. Sixty (60) invited speakers presented their research on Biobased Polymers, Biobased Molecules, Byproduct Utilization, Waste-product Utilization, the Food-Energy-Water Nexus, Nanotech that Drives Sustainability, Food Safety and Security, and Sustainable Food Systems for Health. Contributions to this issue of ACS Food Science & Technology can be generally categorized as leveraging renewable resources for health and nutrition benefits, modifying renewable resources to extend their utility, and computational approaches to help enhance or increase the safety of renewable agricultural resources.

Introducing the DCO‐SCI Prize and Medal Winners 2020 and 2021

Introducing the DCO‐SCI Prize and Medal Winners 2020 and 2021

Enhancing the Visibility of Women in the ACS Division of Medicinal Chemistry (ACS MEDI)

On the occasion of the 2023 International Women's Day on March 8, 2023, we want to celebrate and highlight the contributions of many women volunteers in the American Chemical Society Division of Medicinal Chemistry (ACS MEDI).

From aroma chemistry via bioactives to toxicology—remembering the broad expertise of Michael Granvogl in food science

On March 23, 2022, the field of food science lost a pioneering and impassioned scientist through the tragic and untimely passing of Prof. Michael Granvogl. Born on December 21, 1974 in Munich, Germany Michael’s inquisitive nature led him to study food chemistry at the Technical University of Munich (TUM). After graduating in 1998, he remained at TUM to pursue a doctoral degree (conferred in 2007), then habilitation (2016), qualifying him as Associate Professor in Food Chemistry. In 2019, Michael Granvogl was appointed Full Professor at the Institute of Food Chemistry, University of Hohenheim, Germany where he managed a young and dynamic team of enthusiastic scientists in their pursuits to push the boundaries of food chemistry research in their specialized disciplines. Indeed, Michael was a renowned international subject-matter expert on multiple facets of food chemistry, foremost on aroma-active compounds and food-borne toxicants, with a deep knowledge of their formation and degradation mechanisms, and with skilled application of effective extraction procedures and comprehensive analytical techniques to explore and elucidate their nature. Beyond his teaching and research, Michael was a staunch and dedicated member of the Division of Agricultural and Food Chemistry (AGFD) of the American Chemical Society (ACS), taking active and prominent roles on the executive committee to promote the field and support the next generation of scientists. As a native of the city of Munich, it might be noted that his passion for science, evidenced in lecture theaters and laboratories, was mirrored in his private life through his enthused and loyal support of his native soccer team, FC Bayern Munich. That team must now move forward with the loss of one dedicated fan, but the field of food chemistry – in particular the sub-discipline food bioactives – must overcome the void previously filled with Michael Granvogl’s stalwart presence and must cope with the absence of discoveries that will no longer materialize. There are many researchers in the field who lost a dedicated mentor, an esteemed colleague and a dear friend on that fateful day in spring 2022.

Role of gut microbiota metabolism and biotransformation on dietary natural products to human health implications with special reference to biochemoinformatics approach.

Gut microbiota contributes to diverse mammalian processes including the metabolic functions of drugs. It is a potential new territory for drug targeting, especially for dietary natural compounds such as tannins, flavonoids, steroidal glycosides, anthocyanins, lignans, alkaloids, and others. Because most herbal medicines are orally administered, the chemical profile and corresponding bioactivities of herbal medicines may be altered and implication to ailments by specific microbiota through gut microbiota metabolisms (GMMs) and gut microbiota biotransformations (GMBTs). In this review, briefly introducing the interactions between different categories of natural compounds and gut microbiota produced countless microbial degraded or fragmented metabolites with their biological significance in rodent-based models. From natural product chemistry division, thousands of molecules are produced, degraded, synthesized, and isolated from natural sources but exploited due to lack of biological significance. In this direction, we add a Bio-Chemoinformatics approach to get clues of biology through a specific microbial assault to (Natural products) NPs.

Proceedings of APCE-CECE-ITP-IUPAC 2022

In a demonstration of modern analytical chemistry at its best, the International Interdisciplinary Conference of Chemical Analysis, APCE-CECE-ITP-IUPAC 2022 was held after two years of COVID-19-related delays in Siem Reap, Cambodia. The quadruple meeting included: 18th Asia Pacific International Symposium on Microscale Separations and Analyses, 17th International Interdisciplinary Meeting on Bioanalysis, 28th International Symposium on Electro- and Liquid Phase-Separation Techniques, and IUPAC Special Symposia by Division of Chemistry and the Environment. While, under normal circumstances, these conferences would take place in different countries, we have decided to bring together analytical chemists from all over the world for a conference covering all aspects of modern analytical chemistry. Our goal remained the same: “bring together scientists from different disciplines who may not meet at other meetings”. With plenary and invited lectures delivered by distinguished scientists, this in-person meeting allowed to broaden our knowledge, meet new friends, and start new collaborations. The organizers want to thank all speakers, sponsors, and participants for their support. Please, check the conference web for more information about the history, programs, photos, and videos.

Spotlight on the Winners of the DCO‐SCF 2021 Awards – An Ever Valuable Collaboration with EurJOC

Spotlight on the Winners of the DCO‐SCF 2021 Awards – An Ever Valuable Collaboration with EurJOC

Leroy B. Townsend

Leroy B. Townsend, 88, died Oct. 15, 2022, in Sedona, Arizona. “A renaissance man who had a twinkle in his eye. A dedicated family man. Best known for chemistry, medicinal chemistry, and drug discovery; keenly interested in everything from sports to music. Between graduate degrees, a US Navy underwater explosive ordnance disposal and diving officer. Published nearly 600 papers, had numerous patents, plus book series. Held virtually every office in the Division of Medicinal Chemistry and the International Society of Heterocyclic Chemistry. Cofounded other scientific societies, received the ACS Smissman Bristol Myers Squibb Award and the Gertrude Elion Award from the International Society for Antiviral Research, and became a member of the ACS Hall of Fame.”—John C. Drach, friend, colleague, and collaborator Most recent title: Professor emeritus, University of Michigan Education: BS, chemistry and mathematics, New Mexico Highlands University, 1955; MS, chemistry, New Mexico Highlands University, 1957; PhD, chemistry, Arizona

Happy 25th Anniversary, EurJOC!

Happy 25th Anniversary, EurJOC!

IUPAC Awards in Analytical Chemistry—Call for nominations

Abstract The Analytical Chemistry Division of IUPAC has established two awards, including:

Industrial and Engineering Chemistry Division announces 2023 Division Fellows

Industrial and Engineering Chemistry Division announces 2023 Division Fellows

A Review on The Medicinal And Industrial Applications of N-Containing Heterocycles

Nitrogen-containing heterocycles constitute an important division of organic chemistry. The structural and functional diversity in nitrogen-containing heterocyclic compounds emanates from the presence and nature of the heteroatom that optimizes the compound for a specific application. Nitrogen heterocycles have been found to mimic various endogenous metabolites and natural products, highlighting their pivotal role in current drug design. Their applications are manifold and are predominantly used as pharmaceuticals, corrosion inhibitors, polymers, agrochemicals, dyes, developers,etc. Additionally, their catalytic behavior has rendered these compounds notable precursors in synthesizing various important organic compounds. The rate at which nitrogen heterocycles are synthesized explains this organic chemistry domain's vitality and usefulness. The present review article focuses on nitrogen-containing heterocycles as a versatile scaffold for current applications of organic chemistry.

Residual effect of rock-phosphate and PSB on rice yield and soil properties

Use efficiency of direct application of phosphorus (P) hardly exceeds 15-20% because of fixation to soils. The fixed-P could be utilized subsequently if it is brought to plant usable form. An experiment was conducted at Division of Soil Science and Agricultural Chemistry, ICAR-Indian Agricultural Research Institute, New Delhi during 2017-18 to investigate the residual effects of different P sources like di-ammonium phosphate (DAP), rock phosphate (RP), RP+ phosphorus solubilizing bacteria (PSB) and DAP+RP+PSB on rice yield, P uptake, P dynamics and enzyme activities in an Inceptisol. Results indicated that application of DAP30+RP60+PSB had 20.7, 24.3,19.6, 21.0, 28.1, 33, 15.2, 14.4 and 29.4% higher rice grain and straw yields, grain and straw P uptakes, available and saloid P, dehydrogenase, acid phosphatase and alkaline phosphatase activities respectively, as compared to DAP treatment. Thus, it can be inferred that application of DAP+RP+PSB can reduce fertilizer P consumption by 50%, and support the residual (second) crop better than conventional P-fertilizers, and improve soil available and saloid P status as well as enzymatic activities.

Correlating Computation and Structural Analysis for LiFePO4 through Operando Characterization of Lithium-Ion Pouch-Cell Batteries

X-ray absorption spectroscopy (XAS) is a powerful technique for exploring the electronic and structural characteristics of battery materials. Historically, XAS measurements require synchrotron-based photon sources to achieve necessary sensitivity and energy control, but with breakthroughs in X-ray optics, laboratory-based XAS systems are now available on the commercial market. The Chemistry Division at the Naval Research Laboratory recently acquired an easyXAFS™ system, a laboratory-scale spectrometer that is capable of collecting XANES (X-ray Absorption Near-Edge Spectroscopy) and EXAFS (Extended X-ray Absorption Fine Structure) measurements in the 5–18 keV energy window. This energy range covers K-edge absorptions for the first-row transition metals that are of primary interest for electrochemical energy storage. In order to demonstrate the utility of such a laboratory-based XAS, we perform operando measurements on pouch-cell batteries containing the common lithium-ion battery cathode, LiFePO4 (LFP; lithium iron phosphate), tracking Fe oxidation state and bonding environment as a function of state-of-charge. X-ray absorption spectra collected with the easyXAFS™ compare favorably to those from prior investigations of LFP cells analyzed at synchrotron sources [1]. In parallel with XAS measurements, we perform DFT (Density Functional Theory) computation of the LFP structure. Calculations of LFP show that hole-polaron formation during charging alters the local environment around the Fe ion, decreasing the Fe–O bond length. Bond contraction increases with the addition of the Hubbard "U", which also increases the valence difference (formally 2+/3+). We further refine the computational model for the LFP system by tuning the DFT input parameter “U” to correlate with experimental XAS data.[1] C. T. Love, A. Korovina, C. J. Partridge, K. E. Swider-Lyons, M. E. Twigg, and D. E. Ramaker, J. Electrochem. Soc. 160 (2013) A3153.

In Memoriam - BrJAC mourns the death of Prof. Dr. Carol Hollingworth Collins and recognizes her great contribution to the Analytical Chemistry in Brazil

Professor Carol Collins graduated in Chemistry from Bates College (1952) and obtained her PhD in Organic Physical Chemistry from Iowa State University of Science and Technology (1958), when she was introduced to the recently developed gas–liquid chromatography. She conducted postdoctoral research at the University of Wisconsin and later worked on radiochemistry and nuclear medicine at the Brookhaven National Laboratory and the Western New York Nuclear Research Center in Louvain (Belgium) and Southwest Asia. Professor Collins came to the State University of Campinas (Unicamp) with her husband, Kenneth Collins, in July 1974, during the university’s first decade, and played a leading role in consolidation of the Institute of Chemistry at Unicamp and in the growth of chemistry and analytical chemistry in Brazil. Her first line of research in Brazil was radioanalytical chemistry, later focusing on chromatographic techniques, initially applied to the products of radiochemical reactions and radiation chemistry. Subsequently, her attention was directed to the preparation of stationary phases for liquid chromatography. She gained remarkable achievement in the area of chromatography that allowed her to publish two books that are very popular in Brazil: "Introduction to Chromatographic Methods" (1987) and "Fundamentals of Chromatography" (2006). Her scientific and technological contributions have been recognized through several awards, including the “Marie Curie Award” from the American Association of University Women and the “Simão Mathias Medal” from the Brazilian Chemical Society (SBQ). She also received honors in recognition of the contributions of Unicamp's 40th anniversary, SBQ's 30th anniversary, a tribute from the Journal of the Brazilian Chemical Society, the National Meeting of Analytical Chemistry, the School of Separations and the Brazilian Symposium on Chromatography and Related Techniques (SIMCRO) Medal. For her outstanding performance and leadership in the creation and consolidation of the Analytical Chemistry Division of the Brazilian Chemical Society, her name was recognized in the Carol Collins Medal given to each National Meeting of Analytical Chemistry since the 2018 edition. Professor Collins was also a full member of the Brazilian Academy of Sciences and the Academy of Sciences of São Paulo, and received the title of Professor Emerita of Unicamp on 14 May 2012, in addition to being Emeritus Researcher at the National Council for Scientific and Technological Development (CNPq). Apart from her scientific competence, some characteristics shaped her personality and made her very popular among her colleagues and students: her vast gourmet knowledge, keen taste for caipirinha and coffee, infallible memory, great love for her work and for Brazil, dedication to science, analytical chemistry/chromatography, kindness as a person and her incessant search for justice. She was always receptive to clarifying the doubts of students, teachers and interested parties, which she did with great pleasure, characteristic of those who like to teach and transmit knowledge. The contributions of Professor Collins to the training of human resources, the consolidation and development of the Institute of Chemistry at Unicamp and the analytical chemistry/chromatography sector in Brazil and abroad are immeasurable. Her brilliant trajectory will leave a huge legacy that is difficult to measure and she will remain forever in the memory of those who were fortunate enough to live with her.

Division of Organic Chemistry announces SURF awardees

The recipients of the American Chemical Society’s Division of Organic Chemistry’s Summer Undergraduate Research Fellowships (SURF) for the summer of 2022 are Susanna Angles , Illinois State University; Reece Carew-Lyons , Bryn Mawr College; Catherine Chiang , Scripps College; Damien Cooper , University of Southern Mississippi; Evan Ferry , University of Michigan; Hannah Ford , College of the Holy Cross; Anjali Gurajapu , University of California, Berkeley; Lauren Harstad , Arizona State University; Daniel Hubin , Kansas State University; Sebastian Ibarraran , Yale University; Nikki Keramati , University of Michigan; Madison Maiorano , Stonehill College; Mark Mouch , University of San Diego; Isabelle Petrucci , University of Vermont; Nathan Tang , Northeastern University; and Jason Wu , Boston College. The SURF awards provide $6,000 in funding for summer research opportunities for outstanding undergraduate organic chemistry students. For more information about the program, visit orgn.link/surf .

Division of Organic Chemistry announces SURF awardees

Division of Organic Chemistry announces SURF awardees

Resilience of Chemistry: An Introduction to the Agricultural and Food Chemistry Technical Program at the 262nd American Chemical Society National Hybrid Meeting & Exposition, Both Online and in Atlanta, Georgia.

This is the third special issue of the Journal of Agricultural and Food Chemistry (JAFC) based on the Agricultural and Food Chemistry Division (AGFD) technical program, at the 262nd American Chemical Society National Meeting. This was the first national meeting held in a hybrid format, both virtually and in-person in Atlanta, Georgia, U.S.A., on August 22-26, 2021. The AGFD proudly hosted 12 symposia, including three award symposia. There were 34 sessions held in total, with 143 oral presentations and 49 poster presentations. This meeting was highly successful in terms of attendance, and technology issues experienced at the previous virtual meetings were successfully resolved.