We derive indirect limits on the charm and bottom quark electric dipole moments (EDMs) from paramagnetic AMO and neutron EDM experiments. The charm and bottom quark EDMs generate CP-odd photon-gluon operators and light quark EDMs at the c- and b-quark mass thresholds. These CP-odd operators induce the CP-odd semi-leptonic operator CS and the neutron EDM below the QCD scale that are probed by the paramagnetic and neutron EDM experiments, respectively. The bound from CS is |dc| < 1.3 × 10−20e cm for the charm quark and |db| < 7.6 × 10−19e cm for the bottom quark, with its uncertainty estimated as 10 %. The neutron EDM provides a stronger bound, |dc| < 6 × 10−22e cm and |db| < 2 × 10−20e cm, though with a larger hadronic uncertainty.