AimThis study was conducted to investigate the impacts of scenario-based aging simulation experience (SBASE) on students’ empathy, attitudes toward and willingness to work with older adults. BackgroundInnovative teaching strategies such as SBASE have the potential to provide students with the essential skills required for working with older adults. DesignThis study has a randomized controlled trial. MethodsThis study was conducted in west of Turkiye with 120 health sciences senior year students (45 nursing students, 54 medicine students and 21 physical therapy and rehabilititation students) in 2022-2023. The students were randomly assigned to intervention or control group (IG-CG). The IG received SBASE. Pre- and post-tests (after intervention, 1 and 3 months later) were conducted. Data were collected using the descriptive characteristics form, Kogan's attitudes toward old people scale, basic empathy scale and willingness to work with elderly people scale. ResultsThe IG participants recorded statistically better scores regarding positive attitudes towards older adults, in terms of the group x time interaction (t: 2.521, p: 0.036). However, there was no significant difference in the variables investigated between the groups. ConclusionsSBASE appeared to be effective in improving health sciences students’ positive attitudes towards older adults. Health care providers should have a more positive attitude toward older adults to improve levels of care. Data Availability StatementData and supplementary material related to this article can be obtained from the corresponding author upon request.