Characteristics Of Depression In Patients Research Articles

Mediating effect of resilience in relationship between self-perceived burden and depression in patients with advanced non-small cell lung cancer

Objective To explore the present situation and characteristics of depression in patients with non-small cell lung cancer (NSCLC), and to analyze the mediating role of resilience in the relationship between self-perceived burden and depressive symptom, so as to provide evidence for improving depression in patients. Methods A total of 306 subjects from 5 tertiary hospitals in Changsha, Hunan Province were selected by simple random sampling method.Before their discharge from hospital, those subjects were investigated by self-made social demographic questionnaire, Self-rating Depression Scale(SDS), Self-perceived Burden Scale of Lung Cancer(SPBS-LC) and Connor & Davidson Resilience Scale(CD-RISC). Pearson analysis was used to analyze the correlation among the variables, and Amos 7.0 was used to establish the structural equation model and test the mediating effect. Results (1) The total score of depression was (59.10±8.37). The total scores of resilience and self-perception burden were (52.77±10.12) and (49.64±8.55) in newly-diagnosed advanced non-small cell lung cancer patients.(2) Pearson analysis showed that the total score of depression was negatively correlated with the total score of resilience, optimism, self-improvement and tenacity (P<0.05). The total score of depression was positively correlated with the total score of self-perception burden, physical burden, emotional burden, disease symptoms, social and economic dimensions (P<0.05). (3) Structural equation model analysis showed that resilience played a partial role in mediating between self-perceived burden and depression and mediating effect accounted for 29.8% of the total effect. Conclusion The depressive symptom of the NSCLC patients is at the mild to moderate level.Reducing their self-perceived burden and promoting the resilience of lung cancer patients could alleviate their depressive symptom. Key words: Non-small cell lung cancer; Resilience; Self-perceived burden; Depression; Mediating effect

Clinical characteristics and related risk factors of depression in patients with early COPD.

Background and objectiveAlthough depression is considered one of the comorbidities of COPD, the clinical characteristics of depression in patients with early COPD remain unknown. We aimed to use national-level data to identify the clinical features and risk factors of depression in patients with early COPD.MethodsWe examined 7,550 subjects who were registered in the Korean National Health and Nutrition Examination Survey database of 2014 because that was the only year in which the Patient Health Questionnaire-9 for depression status was administered. Spirometry was used to identify patients with COPD whose forced expiratory volume in 1 second was 50% or more, and these patients were included in the analysis.ResultsOf the 211 subjects with early COPD, 14.2% also had depression, whereas 85.8% did not. The patients with depression were predominantly living alone and had a greater prevalence of diabetes compared with the patients without depression. The overall quality of life of the subjects with depression was lower than that of those without depression, and only the quality of life index correlated significantly with depression severity. In the multivariate regression analysis, female sex (adjusted OR, 1.79; 95% CI, 1.38–2.31; p<0.01), living alone (adjusted OR, 1.86; 95% CI, 1.37–2.51; p<0.01), and low income (adjusted OR, 2.17; 95% CI, 1.55–3.04; p<0.01) were identified as significant risk factors for depression.ConclusionIn patients with early COPD, depression was associated with a low quality of life, and female sex, living alone and low income were significant risk factors for depression.

Clinical characteristics of depression in patients with episodic consumption of and dependence on alcohol

To study clinical and psychopathological features of depression in patients with consumption of and dependence on alcohol. Eighty-nine depressed patients were examined. The first group included patients with depressive disorders complicated by alcoholism. The second group included patients, which used alcohol in depressive phase. Control group included patients with endogenous depression without drinking alcohol. Examinations of patients were carried out using clinical-psychopathological method, MADRS and statistical analysis of the data. Depressive disorders complicated by consumption of and dependence on alcohol were comparable for the clinical picture, family history, premorbid features. At the same time, they had a number of differences. In patients with alcohol abuse in depressive syndrome, anxious and melancholic depressions were more frequent. They were complicated with alcohol dependence, were more severe, had less favorite outcomes and a trend toward prolonged course and were more psychopathologically polymorphic. Characteristics of depression in patients with consumption of and dependence on alcohol will allow for a more accurate differential diagnosis and more adequate treatment of affective disorders.

0590 Characteristics of depression in patients with Multiple Sclerosis (MS) according Beck's Depression Inventory (BDI)

0590 Characteristics of depression in patients with Multiple Sclerosis (MS) according Beck's Depression Inventory (BDI)

Characteristics of sustained depression in patients with acute coronary syndrome (ACS)

Characteristics of sustained depression in patients with acute coronary syndrome (ACS)

Life Course of Depressive Illness and Characteristics of Current Episode in Patients with Double Depression

It has been suggested recently that major depression and concurrent chronic minor depression, or "double depression" (DD), may have a different course and presentation from major depression alone (MDA). The present study compares 41 patients with DD and 60 patients with MDA for differences in life course of depressive illness and characteristics of the current depressive episode. Patients with DD, as compared with patients with MDA, had an earlier age of onset of mood disturbance, more episodes of major depression, and more frequent concurrent anxiety disorders. However, patients with DD were not significantly different from patients with MDA who had greater than a 6-month history of mood disturbance, with regard to life course of illness variable. The characteristics of current depression in patients with DD and MDA were not significantly different. The clinical and theoretical implications of these findings are discussed.