Abstract
Objective To explore the present situation and characteristics of depression in patients with non-small cell lung cancer (NSCLC), and to analyze the mediating role of resilience in the relationship between self-perceived burden and depressive symptom, so as to provide evidence for improving depression in patients. Methods A total of 306 subjects from 5 tertiary hospitals in Changsha, Hunan Province were selected by simple random sampling method.Before their discharge from hospital, those subjects were investigated by self-made social demographic questionnaire, Self-rating Depression Scale(SDS), Self-perceived Burden Scale of Lung Cancer(SPBS-LC) and Connor & Davidson Resilience Scale(CD-RISC). Pearson analysis was used to analyze the correlation among the variables, and Amos 7.0 was used to establish the structural equation model and test the mediating effect. Results (1) The total score of depression was (59.10±8.37). The total scores of resilience and self-perception burden were (52.77±10.12) and (49.64±8.55) in newly-diagnosed advanced non-small cell lung cancer patients.(2) Pearson analysis showed that the total score of depression was negatively correlated with the total score of resilience, optimism, self-improvement and tenacity (P<0.05). The total score of depression was positively correlated with the total score of self-perception burden, physical burden, emotional burden, disease symptoms, social and economic dimensions (P<0.05). (3) Structural equation model analysis showed that resilience played a partial role in mediating between self-perceived burden and depression and mediating effect accounted for 29.8% of the total effect. Conclusion The depressive symptom of the NSCLC patients is at the mild to moderate level.Reducing their self-perceived burden and promoting the resilience of lung cancer patients could alleviate their depressive symptom. Key words: Non-small cell lung cancer; Resilience; Self-perceived burden; Depression; Mediating effect
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More From: Chinese Journal of Behavioral Medicine and Brain Science
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