The aim of this study was to test whether rosella flower extract can reduce uric acid levels after physical activity. Pre- and post-control groups were used in this experimental investigation. Purposive sampling was used to select the individuals, and once they were chosen, they were split into two groups: the treatment group (P) received 500 mg of rosella flower extract, and the control group (K) received a placebo. A total of 20 healthy men aged 19-25 years participated in this study. Data collection was carried out for 1 day starting with collecting data on subject characteristics. After that, the subjects were asked to warm up. Physical activity was carried out afterwards. The activity included running 2400 meters with moderate intensity. Then the baseline data was taken by checking uric acid levels. Then the samples were given a placebo and rosella flower extract to drink directly. 60 minutes later the post-test uric acid level data was taken. The results of this study showed that there was a decrease in uric acid levels in both the control and treatment groups. However, a significant decrease occurred in the group with 500 mg of rosella flower extract intervention. Given its high antioxidant content, we recommend consuming roselle flower extract as an additional supplement after exercise.