The ultimate precision in quantum sensing could be achieved using optimal quantum probe states. However, current quantum sensing protocols do not use probe states optimally. Indeed, the calculation of optimal probe states remains an outstanding challenge. Here, we present an algorithm that efficiently calculates a probe state for correlated and uncorrelated measurement strategies. The algorithm involves a conic program, which minimizes a linear objective function subject to conic constraints on a operator-valued variable. Our algorithm outputs a probe state that is a simple function of the optimal variable. We prove that our algorithm finds the optimal probe state for channel estimation problems, even in the multiparameter setting. For many noiseless quantum sensing problems, we prove the optimality of maximally entangled probe states. We also analyze the performance of 3D-field sensing using various probe states. Our work opens the door for a plethora of applications in quantum metrology.
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