The lighting design of large-space buildings in gymnasiums can impact the indoor luminous and thermal environment, resulting in an uneven light and thermal distribution. This paper investigates the luminous and thermal environment control strategies for high spaces in gymnasiums, by simulating the luminous and thermal environment under different lighting forms and establishing a comprehensive evaluation model. The results show that the weights of the indoor luminous environment, thermal environment, and comprehensive energy consumption change with season and time under different lighting forms, which provides a basis for developing a temporal–spatial partition control strategy. The temporal–spatial partition control strategy is proposed for summer and winter, including the shading angle control under the lighting forms of south-facing side windows, west-facing side windows, and top skylights. Under summer conditions, the south-facing side windows have no shading from 8:00 to 10:00 and 14:00 to 16:00, and the shading angle is 0° from 10:00 to 14:00; the west-facing side windows have no shading from 8:00 to 14:00, the shading angle is 0° from 14:00 to 15:00, and the shading angle is 15° from 15:00 to 16:00; and the top skylight has a shade angle of 15° from 8:00 to 9:00, 30° from 9:00 to 11:00, 45° from 11:00 to 13:00, and no shade from 13:00 to 16:00. Under winter conditions, the south-facing side windows have no shading all day; the west-facing side windows have no shading from 8:00 to 14:00, and the shading angle is 30° from 14:00 to 16:00; and the top skylight has no shading from 8:00 to 13:00, a shading angle of 45° from 13:00 to 15:00, and a shading angle of 75° from 15:00 to 16:00. This paper provides a set of scientific and reasonable luminous and thermal environment regulation strategies for large-space buildings, which can help optimize the building energy consumption and improve the indoor environment quality.