Changes In Vitreous Body Research Articles

Vitreous floaters – etiology, diagnostics and treatment

Vitreous floaters are one of the most common complain of ophthalmological patients. The aetiology of floaters includes pathological process (vitreous haemorrhages, injuries, diabetics or uveitis) and also natural age-related changes in vitreous body. Diagnosis and treatment depends on the severity of the symptoms. Process of posterior vitreous detachment requires particularly careful monitoring, because of potential complications such as retinal tears or retinal detachment. Supplementation with anti-glycation and antioxidant substances allows to reduce complains of patients with vitreous floaters.

Changes in the vitreous body after experimental vitreous hemorrhage in rabbit: An interdisciplinary study.

To explore the changes in vitreous body after vitreous hemorrhage and assess its prognosis from the perspective of vitreoretinal interface. The experiment was performed on 32 New Zealand rabbits (64 eyes), weighing 2500-3000 g for 4 months and unlimited gender, which was injected with 0.2 mL of autologous blood into the center of vitreous cavity-the study group (right eyes), and the control one was treated in the same manner with equal volumes of saline. The rabbits were randomly and equally divided into the following four batches according to the days of observation: Days 3, 7, 14, and 30 after injection. IOP and severity grading were evaluated before rabbits' execution and eyeballs were enucleated. The anterior segment was separated to flow out the vitreous body naturally to detect the liquefaction degree and viscosity. Then, chemical composition of electrolytes, PCT and bFGF were determined by colorimetry and enzyme-linked immunosorbent assay (ELISA). Finally, the incidence of posterior vitreous detachment (PVD) was observed after vitreous sampled. The studies were double-blind. After injection, the extent of vitreous opacity and coagulum size decreased over time. Both the degree of liquefaction and the length of tow differed significantly between two groups at different time points (all p < 0.001). The liquefaction degree in the study group rose obviously from the Day 14, which the viscosity declined significantly on the initial time. Biochemical markers fluctuated temporarily, except for basic fibroblast growth factor (bFGF), which continued to rise and was correlated with the liquefaction degree (r = 0.658, p < 0.001). Besides, the incidence of PVD increased from the 14th day (p < 0.05), and it was highly positively correlated with the number of macrophages (r = 0.934; p < 0.001). After vitreous hemorrhage, the changes of the vitreous body are relatively minor earlier (2-4 weeks), but irreversible later. Specifically, the degree of liquefaction increases with a decrease in viscosity, and the chemotaxis of macrophages and bFGF induce incomplete PVD.

Eye AIDS patholgy evaluation by using ultrasound examination

AbstractPurpose Ultrasound B scan is an important diagnostic method in eye pathology. We want to demonstrate the usefulness of ultrasound B scan in early diagnosis of AIDS symptoms and structural changes in the eyes. 30 years old female with bilateral uveitis was examined. Patient had suddenly unilateral loss of vision acuity.Methods Patient undergo full ophthalmological examination and ultrasound B scan diagnostic examination.Results During 2 weeks patient noticed sudden loss of vision acuity. Slit lamp examination revealed acute anterior uveitis. Fundus examination revealed hard changes in vitreous body. In right eye we diagnosed vitreitis and in left eye was more intensive changes of endophthalmitis. During systemic treatment of toxoplasmosis and AIDS in right eye we noticed full process stabilisation. Acute retinal necrosis and full loss vision we noticed in left eye. Ultrasound B scan revealed only structural changes of vitreous in right eye and vitreous hemorrhages and total retina detachment in left eye.Conclusion We recommend early referral of cases of AIDS pathology in the eyes for baseline Ultrasound scan and follow up scan in 2 weeks, 4 weeks, 3 months and for later time to detect underlying pathology.