High-level Changes Research Articles

Democracy is Complexity. Social Transformation from Below

The temptation to find a working formula for transforming society into a highly regulated, sustainable world-system does not take into account two extremely relevant and interwoven aspects of reality, which can be understood by probing the deeper meaning of these two words: democracy and complexity. Beginning with what is arguably the most mysterious term of the two, complexity, the first point that must be clarified is that “complex” and “complicated” systems are diametrically different: complicated systems are man-made mechanical/artificial systems and as such are controllable, predictable, and possible to break down into their smaller parts. All living systems, instead, are complex, thus the exact opposite: uncontrollable, unpredictable, and impossible to break down into their highly dynamic, interconnected, and interdependent parts. If this sounds familiar, it may be because this is also a passable description of democracy. Complex systems, including democracies, therefore, are made up of an exceedingly large number of smaller, interactive subsystems, or subunits, arranged hierarchically, where the changes “from below” among smaller sub-units trigger changes in higher levels of units, changes which will affect the entire system and its interactions with other systems and with the environment, giving rise to self-organization and emergence. Social transformation is no exception: it must also begin from bottom-up events, from single individuals or grassroots communities, never from a top-down, hetero-directed imposition, even when this is attempted with the noblest of intentions.

A registered re-examination of the effects of leftward prism adaptation on landmark judgements in healthy people.

It has long been known that active adaptation to a shift of the visual field, caused by laterally-displacing prisms, induces short-term sensorimotor aftereffects. More recent evidence suggests that prism adaptation may also stimulate higher-level changes in spatial cognition, which can modify the spatial biases of healthy people. The first reported, and most replicated, higher-level aftereffect is a rightward shift in the point of subjective equality (PSE) for a perceptual bisection task (the landmark task), following adaptation to leftward prisms. A recent meta-analysis suggests that this visuospatial aftereffect should be robustly induced by an extended period of adaptation to strong leftward prisms (15°, ∼26.8 prism dioptres). However, we have been unable to replicate this effect, suggesting that the effect size estimated from prior literature might be over-optimistic. This Registered Report compared visuospatial aftereffects on the landmark task for a 15° leftward prism adaptation group (n=102) against a sham-adaptation control group (n=102). The effect size for the comparison was Cohen's d=.27, 95% CI [-.01, .55], which did not pass the criterion set for significance. A Bayesian analysis indicated that the data were more than 4.1 times as likely under the null than under an informed experimental hypothesis. Exploratory analyses showed no evidence for a rightward shift of landmark judgements in the prism group considered alone, and no relationship between sensorimotor and visuospatial aftereffects. We further found no support for previous suggestions that visuospatial aftereffects are modulated by a person's baseline bias (leftward or rightward) for the landmark task. Null findings are also presented for a preliminary group of 62 participants adapted to 15° leftward prisms, and an additional group of 29 participants adapted to 10° leftward prisms. We do not rule out the possibility that leftward prisms might induce higher-level visuospatial aftereffects in healthy people, but we should be more sceptical about this claim.

Managed Wildfire: A Strategy Facilitated by Civil Society Partnerships and Interagency Cooperation

Federal land managers in the United States are permitted to manage wildfires with strategies other than full suppression under appropriate conditions to achieve natural resource objectives. However, policy and scientific support for “managed wildfire” appear insufficient to support its broad use. We conducted case studies in northern New Mexico and southwestern Utah to examine how managers and stakeholders navigated shifting barriers and opportunities to use managed wildfire from 2018 to 2021. The use of managed wildfire was fostered through an active network of civil society partnerships in one case, and strong interagency cooperation and existing policies and plans in the other. In both, the COVID-19 pandemic, drought, and agency direction curtailed recent use. Local context shapes wildfire response strategies, yet centralized decision-making and policy also can enable or constrain them. Future research could refine the understanding of social factors in incident decision-making, and evaluation of risks and tradeoffs in wildfire response. Implications Managers and stakeholders seeking to restore fire’s ecological roles in their own landscapes through the use of managed wildfires could use these findings to cultivate supportive local environments for their objectives. Both case studies offer examples of how managed wildfires may be facilitated through civil society partnerships and interagency cooperation. Networks of civil society and agency partners can encourage policy change at multiple levels through concerted efforts over time, particularly by building a larger case through localized examples of collaborative projects and a body of regionally relevant scientific evidence. Strong interagency cooperation on both mitigation and response can also foster an environment of mutual understanding, even given differing missions and mandates for managed wildfire. Management implications Federal wildfire response must consider multiple objectives that may compete across scales, social-ecological contexts, and timeframes. These include minimizing negative impacts on human values, responding to immediate risks of fire exposure, managing land sustainably under longer timeframes; and meeting accomplishment targets, such as acres of hazardous fuels reduction, ecological restoration, and other resource objectives. Federal wildfires and land managers are permitted to manage wildfires for natural resource objectives but face challenges of ambiguous terminology, conflicting policies, drought, increasing numbers of homes in wildlands, and unanticipated events, such as the COVID-19 pandemic. Conditions, opportunities, and barriers to manage wildfire vary substantially by locality and are dependent on local actors, yet also subject to higher-level changes in policy direction. Beyond improved risk analytics and decision support tools, enabling social and internal institutional conditions may also facilitate opportunities for use of managed wildfire. Social science can provide evidence and frameworks including concrete lessons learned, expanded use of after-action reviews, process monitoring, briefings with leadership, and science application through boundary-spanning organizations.

Different Phenylalanine Pathway Responses to Cold Stress Based on Metabolomics and Transcriptomics in Tartary Buckwheat Landraces.

Tartary buckwheat (Fagopyrum tataricum) is strongly adapted to growth in adverse environments. In Liangshan, the Yi people cultivate different Tartary buckwheat landraces in different habitats. In this study, we aimed to understand the molecular differences in transcriptomic and metabolomic responses underlying cold tolerance between two Tartary buckwheat landraces (TM and RG) cultivated at different altitudes. After cold treatment, TM showed normal growth in the seedling stage and had significantly higher total flavonoids (16.53 mg/g, 1.47 times), rutin (5.73 mg/g, 1.32 times), and quercetin (0.08 mg/g, 2.67 times), which were higher than those in RG. In addition, TM showed higher-level changes in carbon and nitrogen metabolism than RG. Combined transcriptome and metabolomic analyses showed that phenylpropanoid biosynthesis was upregulated after cold treatment, and in TM, rutin synthesis was upregulated with a higher-level response to cold stress. RG showed higher expression in anthocyanins in response to cold stress. In addition, 24 structural genes involved in flavonoid synthesis, including 6 PAL, 3 C4H, 2 4CL, 2 CHS, 1 CHI, 3 F3H, 3 DFR, 1 FLS, 1 F3'H, and 4 GTR genes, were identified. These results will provide sufficient information for breeding Tartary buckwheat with high cold tolerance and constructing rutin high-yield varieties based on genetic engineering.

Workplace Healthy Lifestyle Determinants and Wellbeing Needs across the Preconception and Pregnancy Periods: A Qualitative Study Informed by the COM-B Model.

Overweight and obesity present health risks for mothers and their children. Reaching women during the key life stages of preconception and pregnancy in community settings, such as workplaces, is an ideal opportunity to enable health behavior change. We conducted five focus groups with 25 women aged between 25 and 62 years in order to investigate the determinants of healthy lifestyle behaviors, weight management, and wellbeing needs during the preconception and pregnancy periods in an Australian university workplace. Discussions explored women’s health and wellbeing needs with specific reference to workplace impact. An abductive analytical approach incorporated the capability, opportunity, and motivation of behavior (COM-B) model, and four themes were identified: hierarchy of needs and values, social interactions, a support scaffold, and control. Findings highlight the requirement for greater organization-level support, including top-down coordination of wellbeing opportunities and facilitation of education and support for preconception healthy lifestyle behaviors in the workplace. Interventionists and organizational policy makers could incorporate these higher-level changes into workplace processes and intervention development, which may increase intervention capacity for success.

Body position and motor imagery strategy effects on imagining gait in healthy adults: Results from a cross-sectional study.

BackgroundAssessment of changes in higher levels of gait control with aging is important to better understand age-related gait instability, with the perspective to improve the screening of individuals at risk for falls. The comparison between actual Timed Up and Go test (aTUG) and its imagined version (iTUG) is a simple clinical way to assess age-related changes in gait control. The modulations of iTUG performances by body positions and motor imagery (MI) strategies with normal aging have not been evaluated yet. This study aims 1) to compare the aTUG time with the iTUG time under different body positions (i.e., sitting, standing or supine) in healthy young and middle age, and older adults, and 2) to examine the associations of body positions and MI strategies (i.e., egocentric versus allocentric) with the time needed to complete the iTUG and the delta TUG time (i.e., relative difference between aTUG and iTUG) while taking into consideration clinical characteristics of participants.MethodsA total of 60 healthy individuals (30 young and middle age participants 26.6±7.4 years, and 30 old participants 75.0±4.4 years) were recruited in this cross-sectional study. The iTUG was performed while sitting, standing and in supine position. Times of the aTUG, the iTUG under the three body positions, the TUG delta time and the strategies of MI (i.e., ego representation, defined as representation of the location of objects in space relative to the body axes of the self, versus allocentric representation defined as encoding information about body movement with respect to other object, the location of body being defined relative to the location of other objects) were used as outcomes. Age, sex, height, weight, number of drugs taken daily, level of physical activity and prevalence of closed eyes while performing iTUG were recorded.ResultsThe aTUG time is significantly greater than iTUG while sitting and standing (P<0.001), except when older participants are standing. A significant difference is reported between iTUG while sitting or standing and iTUG while supine (P≤0.002), higher time being reported in supine position. The multiple linear regressions confirm that the supine position is associated with significant increased iTUG (P≤0.04) and decreased TUG delta time (P≤0.010), regardless of the adjustment. Older participants use the allocentric MI while imagining TUG more frequently than young and middle age participants, regardless of body positions (P≤0.001). Allocentric MI strategy is associated with a significant decrease in iTUG (P = 0.037) only while adjusting for age. A significant increase of iTUG time is associated with age (P≤0.026).ConclusionsSupine position while imagining TUG represents a more accurate position of actual performance of TUG. Age has a limited effect on iTUG performance but is associated with a change in MI from ego to allocentric representation that decreases the iTUG performances, and thus increases the discrepancy with aTUG.

How (not) to Argue For Moral Enhancement: Reflections on a Decade of Debate

The controversy over moral bioenhancement has fallen into a stalemate between advocates and critics. We wish to overcome this stalemate by addressing some of the key challenges any moral enhancement project has to meet. In particular, we shall argue that current proposals are unpersuasive as they, first, fail to diagnose the often complex causes of contemporary moral maladies and, second, are premised on methodological individualism. Focusing on brains and minds neglects social and environmental factors. Solving the mega-problems of today very likely requires more than transforming individual brains, it requires structural and higher-level changes. By itself, moral bioenhancement is thus insufficient for solving these problems. Moreover, we outline some of the yet unresolved problems of (democratic) legitimacy a mandatory state-run bioenhancement project faces and show why they cannot be defused through analogies with moral education. Finally, normatively less worrisome means of enhancing morality, such as psychotherapies affording self-exploration, are already available. Moral bioenhancement may thus not even be necessary for solving today’s mega problems. The overemphasis on speculative future technological fixes may cloud the view on possibilities to tackle pressing problems instantly.

Changes in primary school pupils' conceptions of water in the context of Science, Technology, and Society (STS) instruction

ABSTRACTPupils' conceptual change processes that have led to long-term changes in learning processes can be very challenging and interwoven with several issues. Meanwhile, school learning is often determined as fragmented, without providing connections to pupils' different life and societal contexts. In this study, Science, Technology, and Society (STS) instruction was conducted to enhance primary school pupils' conceptual change process with water-related concepts. Pupils (N = 41) studied water over four-week period and considered water-related concepts and phenomena in scientific, societal, and technological contexts. Before and after STS instruction, the pupils wrote the essays and based on an analysis of the essays, 10 pupils were selected for interviews. Prior the STS instruction, the pupils' conceptions of water were descriptive and were situated in regard to their everyday lives, and pupils considered their water-use subjectively. Pupils rarely were able to explain the relationships between the concepts or phenomena. After the STS instruction, the scientific explanations increased, and water was understood more globally, and different issues such as water states and water circulation were linked to each other. In this study, the pupils' conceptual change process mainly occurred as a reorganisation of conceptual hierarchies but also included some insights for the higher level changes. In addition, learning contexts seem to have crucial roles for the changes. The learning contexts supported the pupils to consider water as broad, interlinked phenomena. STS instruction dared the pupils to consider water phenomenon as a global issue.

Annotated check list of the Pyraloidea (Lepidoptera) of America North of Mexico

An annotated check list of Pyraloidea of North America north of Mexico is presented, including 861 Crambidae and 681 Pyralidae with 1542 total species. It includes all new species described, tropical species with new records in the United States, and species introduced from Europe and Asia since 1983. The Notes section provides the seminal citations, data and/or commentary to all changes since 1983 for easy and future reference. In addition, this list proposes seven new generic combinations, the transfer of a phycitine species, Salebria nigricans (Hulst), to Epipaschiinae and its syn. n. with Pococera fuscolotella (Ragonot), and three new records for the United States. Purposefully, no new taxa are described here, but we found a gradual increase of 10% in the number of species described since 1983. Finally, we also include a list of thirteen species not included or removed from the MONA list. Many higher-level changes have occurred since 1983 and the classification is updated to reflect research over the last 30 years, including exclusion of Thyrididae and Hyblaeidae from the superfamily and recognition of Crambidae and Pyralidae as separate families. The list includes multiple changes to subfamilies based on morphology such as the synonymization of the Dichogamini with the Glaphyriinae, but also incorporating recent molecular phylogenetic results such as the synonymization of the Evergestinae with the Glaphyriinae.

Layered change log model: bridging between ontology change representation and pattern mining

To date, no ontology change management system exists that records the ontology changes based on the different levels of granularity. Once changes are performed using elementary-level change operations, they are recorded in the database at the elementary level accordingly. Such a change representation procedure is not sufficient to represent the intuition behind any applied change and thus, cannot capture the semantic impact of a change. In this paper, we discuss the recording of the applied ontology changes in the form of a layered change log. This knowledge-based layered change log facilitates the detection of the similarities within different time series, mining of change patterns and reuse of the knowledge. Here, the lower-level change log is utilised for recording of the applied ontology changes operational and mining of the change patterns analytical. The higher-level change log supports a comprehensive understanding of the ontology evolution.

Ontology Change Management and Identification of Change Patterns

Ontologies can support a variety of purposes, ranging from capturing the conceptual knowledge to the organisation of digital content and information. However, information systems are always subject to change and ontology change management can pose challenges. In this sense, the application and representation of ontology changes in terms of higher-level change operations can describe more meaningful semantics behind the applied change. In this paper, we propose a four-phase process that covers the operationalization, representation and detection of higher-level changes in ontology evolution life cycle. We present different levels of change operators based on the granularity and domain-specificity of changes. The first layer is based on generic atomic level change operators, whereas the next two layers are user-defined (generic/domain-specific) change patterns. We introduce layered change logs for the explicit operational representation of ontology changes. We formalised the change log using a graph-based approach. We introduce a technique to identify composite changes that not only assists in formulating ontology change log data in a more concise manner, but also helps in realizing the semantics and intent behind any applied change. Furthermore, we identify frequent change sequences that are applied as a reference to discover reusable, often domain-specific and usage-driven change patterns. We describe the pattern identification algorithms and evaluate their performance.

Motor cortex and gait in mild cognitive impairment: a magnetic resonance spectroscopy and volumetric imaging study

Gait disorders are common in the course of dementia, even at the stage of mild cognitive impairment, owing to probable changes in higher levels of motor control. Since motor control message is ultimately supported in the brain by the primary motor cortex and since cortical lesions are frequent in the dementia process, we hypothesized that impairments of the primary motor cortex may explain the early gait disorders observed in mild cognitive impairment. Our purpose was to determine whether the neurochemistry of the primary motor cortex measured with proton magnetic resonance spectroscopy, and its volume, were associated with gait performance while single and dual-tasking in mild cognitive impairment. Twenty community dwellers with mild cognitive impairment, aged 76 years (11) [median (interquartile range)] (30% female) from the 'Gait and Brain Study' were included in this analysis. Gait velocity and stride time variability were measured while single (i.e. walking alone) and dual tasking (i.e. walking while counting backwards by seven) using an electronic walkway (GAITRite System). Ratios of N-acetyl aspartate to creatine and choline to creatine and cortical volume were calculated in the primary motor cortex. Participants were categorized according to median N-acetyl aspartate to creatine and choline to creatine ratios. Age, gender, body mass index, cognition, education level and subcortical vascular burden were used as potential confounders. Participants with low N-acetyl aspartate to creatine (n = 10) had higher (worse) stride time variability while dual tasking than those with high N-acetyl aspartate to creatine (P = 0.007). Those with high choline to creatine had slower (worse) gait velocity while single (P = 0.015) and dual tasking (P = 0.002). Low N-acetyl aspartate to creatine was associated with increased stride time variability while dual tasking (adjusted β = 5.51, P = 0.031). High choline to creatine was associated with slower gait velocity while single (adjusted β = -26.56, P = 0.009) and dual tasking (adjusted β = -41.92, P = 0.022). Cortical volume correlated with faster gait velocity while single (P = 0.029) and dual tasking (P = 0.037), and with decreased stride time variability while single tasking (P = 0.034). Finally, the probability of exhibiting abnormal metabolite ratios in the primary motor cortex was 63% higher among participants with major gait disturbances in dual task. Those with compromised gait velocity in dual task had a 2.05-fold greater risk of having a smaller cortical volume. In conclusion, the neurochemistry and volume of the primary motor cortex were associated with gait performance while single and dual tasking. Stride time variability was mainly sensitive to neuronal function (N-acetyl aspartate to creatine), whereas gait velocity was more affected by inflammatory damage (choline to creatine) and volumetric changes. These findings may contribute to a better understanding of the higher risks of mobility decline and falls in subjects with mild cognitive impairment.

Time Issues in Multilevel Interventions for Cancer Treatment and Prevention

The concept of time introduces important complexities in estimating intervention effects, program and evaluation design, and measurement and analysis of individual change in multilevel interventions (MLIs). Despite growing recognition that time is a critical element for assessing both individual-level outcomes and higher-level changes in organizational, community, and policy contexts, most MLI designs and evaluations have not addressed these issues. In this chapter we discuss 1) conceptualizing disease life-course and treatment theory in MLIs, 2) approaches to incorporating time in research and program design for MLIs in cancer treatment and prevention, 3) analysis of time-varying multilevel data in the context of cancer treatment and prevention, and 4) resource considerations and trade-offs of incorporating time as a dimension of MLIs and analysis. Although analytic techniques for analyzing time-related phenomena are becoming more available and powerful, there has not been corresponding progress made in the development of theory to guide the application of these techniques in program design and implementation.

An annotated checklist and bibliography of the land and freshwater snails of México and Central America

The checklist of the non-marine gastropod fauna summarizes the known species and subspecies that are recognized from México and Central America. It is an annotated list of 1800 terminal taxa presented in a hierarchical framework. These include 1502 native species plus 278 native subspecies, and 20 introduced species. The native species include 175 aquatic operculates, 84 aquatic pulmonates, 130 terrestrial operculates, and 1112 terrestrial pulmonates. In most cases in order to be as objective as possible the list uncritically records the most recent assignment of terminal taxa. In a few instances some changes are deemed necessary. For higher-level changes competing schemes are treated equally. In cases of terminals and higher taxa, readers are directed to the systematic works that discuss relevant taxonomy. It is anticipated that the annotated list will be a useful resource for everyone interested in non-marine gastropods and their nomenclature. In addition to clarifying some issues or points of confusion, this list should also provide an impetus for future work aimed at clarifying and resolving areas of taxonomic disagreement and/or uncertainty, and to make better known the non-marine molluscan fauna of México and Central America.

Myconet Volume 14. Part One. Outline of Ascomycota—2009. Part Two. Notes on Ascomycete Systematics. Nos. 4751–5113

Abstract Part One presents the current classification that includes all accepted genera and higher taxa above the generic level in the phylum Ascomycota. It is based on the changes listed in Myconet notes 4751–5113. In the current outline, three subphyla (Pezizomycotina, Saccharomycotina, Taphrinomycotina) are accepted. Taphrinomycotina includes four classes (Neolectomycetes, Pneumocystidomycetes, Schizosaccharomyces, Taphrinomycetes). Saccharomycotina consists of one class and Pezizomycotina includes eleven classes (Arthoniomycetes, Dothideomycetes, Eurotiomycetes, Geoglossomycetes, Laboulbeniomycetes, Lecanoromycetes, Leotiomycetes, Lichinomycetes, Orbiliomycetes, Pezizomycetes, Sordariomycetes). Part Two presents 363 notes on the taxonomy and nomenclature of ascomycetes (Ascomycota) at the generic and higher levels. Numerous changes in higher levels resulted from multi-authored phylogenetic papers resulting from the AFTOL and Deep Hyphae projects, especially a publication on a revised fungal classifica...

Imagined Timed Up & Go test: A new tool to assess higher-level gait and balance disorders in older adults?

Background Few studies have explored motor imagery (MI) as a way of accessing the higher-level of control of complex body movements involved in gait or balance. The objective of this study was 1) to measure and compare the time needed to complete the Timed Up & Go test (TUG), the time needed to imagine performing the same test (iTUG) and to calculate the time difference between both of these conditions (delta time) in a sample of young and older adults, and 2) to examine whether there was an association between the Timed Up & Go test results (TUG, iTUG, delta time), age and cognitive decline. Methods A total of 162 subjects (38 healthy young adults, mean age 25.7 ± 2.3 years, 73.7% women and 124 older inpatients, mean age 85.3 ± 6.5 years, 76.6% women) were included in this cross-sectional study. The mean ± SD of TUG, iTUG and delta time, age and the Mini Mental State Examination (MMSE) score were used as main outcomes. Results Age was associated with an increase in time of TUG ( P < 0.001) and of delta time ( P = 0.015), and with a decrease in time of iTUG ( P < 0.001), whereas cognitive decline was only associated with increase in delta time ( P = 0.030). There was an increase in time of TUG ( P < 0.001) and in delta time ( P < 0.001) for subjects who used a walking aid. The increase in delta time depended on the MMSE score when the subjects did not use a walking aid ( P for trend = 0.001). Conclusions iTUG is clinically feasible among frail older adults and may quickly inform any clinician about higher-level changes in control of gait and balance in older adults.