This study examines the uniaxial compressive mechanical properties of after high temperature bamboo scrimber, taking into account the combined effects of temperature, constant temperature duration, and moisture content. A series of 46 uniaxial compression tests were conducted on bamboo scrimber under various conditions to investigate the failure modes after high temperatures. The analysis focuses on the changes in compressive elastic modulus and peak stress of bamboo scrimber parallel and perpendicular to the grain, in relation to temperature, constant temperature duration, and moisture content. The findings reveal that below 180℃, diagonal shear failure and Y-type shear failure are the primary failure modes for specimens parallel to the grain, while diagonal shear failure predominates for specimens perpendicular to the grain. Above 180℃, bond failure and eccentric crushing become the main failure modes for specimens parallel and perpendicular to the grain, respectively. The peak compressive stress decreases significantly beyond 180℃, with a slower decrease observed as moisture content increases. Constant temperature duration has a notable impact on peak stress, with longer durations resulting in lower peak stress at the same temperature. Although temperature has a lesser effect on the elastic modulus compared to peak stress, empirical formulas were derived to establish the relationship between compressive elastic modulus and peak stress reduction coefficient with variations in temperature, constant temperature duration, and moisture content based on the experimental data.