Changes In Patterns Research Articles

Hypertension disrupts the vascular clock in both sexes.

Blood pressure (BP) displays a circadian rhythm and disruptions in this pattern elevate cardiovascular risk. Although both central and peripheral clock genes are implicated in these processes, the importance of vascular clock genes is not fully understood. BP, vascular reactivity, and the renin-angiotensin-aldosterone system display overt sex differences, but whether changes in circadian patterns underlie these differences is unknown. Therefore, we hypothesized that circadian rhythms and vascular clock genes would differ across sex and would be blunted by angiotensin II (ANG II)-induced hypertension. ANG II infusion elevated BP and disrupted circadian patterns similarly in both males and females. In females, an impact on heart rate (HR) and locomotor activity was revealed, whereas in males hypertension suppressed baroreflex sensitivity (BRS). A marked disruption in the vascular expression patterns of period circadian regulator 1 (Per1) and brain and muscle aryl hydrocarbon receptor nuclear translocator like protein 1 (Bmal1) was noted in both sexes. Vascular expression of the G protein-coupled estrogen receptor (Gper1) also showed diurnal synchronization in both sexes that was similar to that of Per1 and Per2 and disrupted by hypertension. In contrast, vascular expression of estrogen receptor 1 (Esr1) showed a diurnal rhythm and hypertension-induced disruption only in females. This study shows a strikingly similar impact of hypertension on BP rhythmicity, vascular clock genes, and vascular estrogen receptor expression in both sexes. We identified a greater impact of hypertension on locomotor activity and heart rate in females and on baroreflex sensitivity in males and also revealed a diurnal regulation of vascular estrogen receptors. These insights highlight the intricate ties between circadian biology, sex differences, and cardiovascular regulation.NEW & NOTEWORTHY This study reveals that ANG II-induced hypertension disrupts the circadian rhythm of blood pressure in both male and female mice, with parallel effects on vascular clock gene and estrogen receptor diurnal patterns. Notably, sex-specific responses to hypertension in terms of locomotor activity, heart rate, and baroreflex sensitivity are revealed. These findings pave the way for chronotherapeutic strategies tailored to mitigate cardiovascular risks associated with disrupted circadian rhythms in hypertension.

Numerical analysis of gas-solid flow erosion in different geometries as alternatives to a standard pipe elbow

This study was conducted with the aim of replacing different geometric fittings instead of the standard 90° elbow and trying to change the flow pattern to reduce erosion damage. Among fittings, the elbows are at a more serious risk. Numerical investigation of the present erosion with the novelty of research on non-spherical particles and changes in the impact angle of particles along with fluid flow using eight new proposed fittings, including two miter fittings, three blinded fittings, one reducer elbow fitting, and two spherical elbows fittings in comparison with the standard 90° elbow was controlled. The numerical simulation of the gas-solid two-phase flow of non-spherical particles was studied using the Euler-Lagrange approach. To carry out the study numerical, first, the gas flow was modeled by the Navier-Stokes equations and the turbulent Reynolds stress model, and then the solid particles were injected using Newton's equation. Finally, the erosion was calculated using Grant and Tabakoff model of the restitution of particles of after hitting the wall and the erosion model of Oka. The amount of erosion caused by changes in the flow pattern was investigated to evaluate the performance of the new proposed fittings. Numerical results for the most critical mode (Vin = 27 m/s and DP = 300 μm) showed that the new proposed fittings increase the erosion resistance by 22.5 % to 39.6 % compared to the standard 90° elbow. Also, in this research, the effect of different parameters including flow velocity, particle diameter size, particle input rate, and particle rotation on erosion were investigated.

Prediction of approaching trains based on H‐ranks of track vibration signals

AbstractThis paper introduces a method for forecasting the arrival of trains by analyzing track vibration signals. The proposed algorithms, based on H‐ranks of track vibration signals, can generate early alerts for approaching trains. These algorithms are robust to additive noise and environmental conditions. The theoretical foundation of the method involves the application of matrix operations to detect significant changes in vibration patterns, indicating an approaching train.

Changes in the Spatial Patterns of Near‐Surface Soil Moisture and Environmental Controlling Factors Before and After a Landslide

Changes in the Spatial Patterns of Near‐Surface Soil Moisture and Environmental Controlling Factors Before and After a Landslide

Changes in Healthcare Utilization After the 2022 Seoul Metropolitan Flood: Applying a Generalized Synthetic Control Approach.

Floods can have adverse health effects and impose a burden on healthcare systems. However, the potential consequences of floods on specific medical causes in densely populated metropolitan cities has not been characterized yet. Therefore, we evaluate the changes in healthcare utilization patterns after the 2022 Seoul flood using nationwide health insurance data. Based on the flood inundation map, districts within the flooded municipalities of Seoul were classified as severe-(n=12), mild-(n=22), or non-(n=38) flood-affected districts. Capitalizing on the timing of the flood as a natural experiment, a generalized synthetic control method was applied to estimate changes in the number of disease-specific hospital visits in flood-affected districts during 2weeks after the flood. We found excess hospital visits for external injuries (20.2 visits, 95% CI: -6.0, 45.2) and fewer visits for pregnancy and puerperium (-3.0 visits, 95% CI: -5.1, -0.5) in residents of flooded districts. When comparing severe- and non-flood districts, the increase in hospital visits for external injuries (56.2 visits, 95% CI: 17.2, 93.2) and a decrease in hospital visits related to pregnancy and puerperium (-5.3 visits, 95% CI: -8.4, -1.6) were prominent in residents living in severe-flood affected districts. Disease specific analysis showed an increase in hospital visits for injuries to the elbow and forearm, ankle and foot injuries, and chronic lower respiratory diseases in severe-flood-affected districts. However, these impacts were not observed when comparing the mild- and non-flood-affected districts. Our study suggests an immediate and substantial change in medical demand following flood exposure, highlighting the importance of public health responses after flood events.

Asymmetric competition for habitats between the temperate Japanese eel Anguilla japonica and the tropical Indo-Pacific eel A. marmorata

Habitat segregation is a common phenomenon among anguillids in rivers where multiple species coexist. However, despite the growing need to conserve their river habitats, the mechanisms underlying such segregation remain unknown. Here, we conducted tank experiments to investigate the competitive superiority for habitats between the temperate Japanese eel Anguilla japonica and the tropical Indo-Pacific eel Anguilla marmorata, which co-occur in East Asian subtropical rivers. Using eight interspecific pairs of these two species of comparable total length, we compared the use of a single pipe shelter, recorded over a 24-h experimental period, between solitary and paired conditions. The changes in shelter use patterns between conditions indicated that in the paired condition, the shelter was occupied by A. marmorata in five pairs (62.5%) by the end of the experiment while A. japonica appeared to occupy the shelter in only one pair (12.5%). Furthermore, agonistic behaviors, which occurred mainly at night, such as biting and head-butting, were observed much more frequently for A. marmorata toward A. japonica (mean ± standard deviation: 23.2 ± 36.6 times per individual) than for A. japonica toward A. marmorata (0.4 ± 0.5 times per individual), indicating an asymmetry in aggressiveness. These results suggest that A. marmorata can negatively affect the diurnal habitat use and nocturnal activities of sympatric A. japonica. These findings, combined with those from previous field studies, suggest that A. marmorata may competitively exclude A. japonica from stream habitats with large substrate sizes. This asymmetric competition can contribute to shaping their riverine distribution and composition within rivers where they co-occur.

Effects of Carrier’s sex on the outcome of embryos and pregnancies in 412 couples undergoing preimplantation genetic testing for structural rearrangements

Study designTo ascertain whether the carrier’s sex affects the outcome of embryos and pregnancies in couples undergoing preimplantation genetic testing for structural rearrangements (PGT-SR). MethodsThis retrospective study comprised 412 couples with reciprocal translocations (RecT), Robertsonian translocations (RobT), or inversions (INV) between January 2017 and October 2022. We applied next-generation sequencing (NGS) on 2588 embryos after trophectoderm (TE) biopsy. ResultsGenetically transferable blastocyst rate was higher in the male carrier group (34.0 % vs 31.7 %, P = 0.013) relative to the female carrier group whereas other embryo and pregnancy outcomes remained similar. Further analysis revealed that this result was primarily due to the alteration of segregation patterns in the RobT subgroup, in which the proportion of alternate segregation was higher (84.3 % vs 66.4 %, P < 0.001) in male carriers compared with female carriers. In the RecT subgroup, the genetically transferable blastocyst rate between male and female carriers was similar although the segregation models also changed, such that the frequency of the adjacent-1 segregation pattern was higher in male carriers than in female carriers (42.5 % vs 34.7 %, P = 0.002). In addition, interchromosomal effect (ICE) did not differ between male and female carriers although ICE was lower in male carriers of the RobT subgroup (pure ICE: 35.50 % vs 44.30 %, P = 0.14; total ICE: 35.50 % vs 40.30 %, P = 0.32) and higher in male carriers of the INV subgroup (pure ICE: 42.3 % vs 37.20 %, P = 0.33; total ICE: 40.90 % vs 36.00 %, P = 0.36). ConclusionsThe carrier’s sex was closely associated with the genetically transferable embryo rate in couples undergoing PGT-SR, principally resulted from the change in segregation pattern in the RobT subgroup but not in the RecT and INV subgroups.

Application of omega 3,6 with Moringa oleifera suplemented vitamin E on rumen fluid characteristics, microbial protein synthesis, and methane gas production in goats on suboptimal lands

Changes in feeding patterns were needed to overcome the problem of methane gas emissions from ruminant livestock and the problem of low productivity at the smallholder livestock level. This solution involves direct action against the gas produced in the stomach of ruminants by providing feed containing active substances to reduce the microbes that produce gas in the stomach. One alternative feed that was often used as a promoter of improving rumen fluid characteristics was the use of omega 3.6 sources together with Moringa leaves enriched with vitamin E. This research aimed to investigate the effect of feeding on methane gas production in goats. The research method used a Randomized Block Design (RAK) with four treatments and five replications in vitro. From the research results, it could be concluded that the use of omega 3.6 together with Moringa leaves enriched with vitamin E was able to reduce methane gas production by 25.62% with a Volatile Fatty Acid (VFA) value of 144.53 mM, pH around 6.99, NH3 11.87 mg/100ml, microbial biomass 20.42 mg/ml, microbial protein 217.58mg/ml, bacterial colony 5.34x109 cells/ml and protozoa population 29x106 cells/ml. This conclusion shows that the use of omega 3.6 with Moringa oleifera supplemented with vitamin E has the potential to consistently improve rumen fluid characteristics and reduce methane gas emissions by using a combination of omega 3.6 sources and Moringa leaves in suboptimal land, as well as vitamin E supplementation.

Changes in global methylation patterns of Mytilus galloprovincialis exposed to microplastics

Microplastics (MPs) disturb the normal activity of aquatic organisms at different levels, causing physiological stress and altering feeding, growth, and reproduction. Alterations of epigenetic patterns due to exposure to MPs have scarcely been studied in invertebrates. In this study, Mytilus galloprovincialis mussels (N = 61) were intermittently exposed to different concentrations of pure polystyrene microbeads for three weeks. The concentrations used in this research were similar to those currently found in certain polluted environments (E1), as well as higher doses to which mussels could be further exposed (E2 and E3). After exposure period, the global methylation patterns were investigated using Amplified Fragment Length Polymorphism (AFLPs). Significantly lower methylation was found in exposed groups compared to the control group. The level of hypomethylation increased with the concentration of microbeads. Similar results were found from field samples inhabiting two sites differentially MPs-polluted. The implications of this discovery were analysed and discussed, noting the already known effects of MPs on metabolism and cell division. Further studies on this and other sentinel organisms are recommended to understand the response of the aquatic species to the currently increasing MPs pollution.

Integrated analyses of the transmission history of SARS-CoV-2 and its association with molecular evolution of the virus underlining the pandemic outbreaks in Italy, 2019-2023

BackgroundItaly was significantly affected by the COVID-19 pandemic, experiencing multiple waves of infection following the sequential emergence of new variants. Understanding the transmission patterns and evolution of SARS-CoV-2 is vital for future preparedness. MethodsWe conducted an analysis of viral genome sequences, integrating epidemiological and phylodynamic approaches, to characterize how SARS-CoV-2 variants have spread within the country. ResultsOur findings indicate bidirectional international transmission, with Italy transitioning between importing and exporting the virus. Italy experienced four distinct epidemic waves, each associated with a significant reduction in fatalities from 2021 to 2023. These waves were primarily driven by the emergence of VOCs such as Alpha, Delta, and Omicron, which were reflected in observed transmission dynamics and effectiveness of public health measures. ConclusionsThe changing patterns of viral spread and variant prevalence throughout Italy's pandemic response underscore the continued importance of flexible public health strategies and genomic surveillance, both of which are crucial for tracking the evolution of variants and adapting control measures effectively to ensure preparedness for future outbreaks.

Colonization profiles of gut microbiota in goat kids from neonatal to weaning period

Understanding the colonization and change patterns of gut microbiota is pivotal for comprehending host health. As a newly cultured breed, the studies on the gut microbiota of Tianfu goats remain limited. This study aimed to address this gap by analyzing the microbial composition and colonization patterns of fecal samples collected from goat kids from birth to weaning. Fecal samples were collected on days 0, 7, 14, 21, 28, 35, 42, 49, 53, 55, 57, and 64, and the changes and colonization patterns of microorganisms were analyzed through high-throughput 16S rRNA sequencing. The results showed that the abundance of fecal microbiota in goat kids gradually increased over time, followed by a decrease after weaning and stabilization, with reduced individual differences. The colonization of fecal microorganisms mainly presented three different stages: days 0–14, days 21–49, and days 53–64. During the suckling period, the relative abundance of Proteobacteria (72.34%) was the highest, followed by Firmicutes (21.66%). From 21 days old, the microbiota in goat kids gradually to be diverse, with Lachnospiraceae and Ruminococcaceae being dominant. During post-weaning, Ruminococcaceae (30.98–33.34%) was becoming prominence which helpful for cellulose decomposition. LEfSe analyzed three important time points (d0 vs. d7, d7 vs. d14, d49 vs. d53, LDA score &amp;gt; 4 and p &amp;lt; 0.05), 53 microbial communities with stage differences were identified. Functional prediction using PICRUSt revealed that differential microbial communities are mainly related to carbohydrate and amino acid metabolism pathways. Overall, this study addresses the intricate relationship between ages, diets, and microbiota compositions in Tianfu goat kids, and also offering insights into microorganisms-host interactions.

The reciprocal relation between rising longevity and temperature-related mortality risk in older people, Spain 1980–2018

Temperature-related mortality mostly affects older people and is attributable to a combination of factors. We focussed on a key non-temperature factor – rising longevity – and aimed to quantify its reciprocal relation with temperature-related mortality risk in Spain over 1980–2018.We obtained average annual temperature-attributable deaths among people aged 65y+, by sex and age group, for different temperature ranges (extreme cold, moderate cold, moderate heat, and extreme heat), from a previous study. Combining this with population and mortality data as well as life table information, we used: (i) a counterfactual approach to assess the contribution of rising longevity to changes in the absolute risk of temperature-related mortality, and (ii) decomposition to assess the contribution of changes in temperature-related mortality to changes in longevity and its variation (lifespan inequality).Rising longevity led to considerable declines in the absolute risk of temperature-related mortality in females and males across the entire temperature range. For extreme heat, it accounted for about a 30 % decrease in absolute risk (half of the total decrease over the study period). For moderate and extreme cold, it accounted for about a 20 % fall in absolute risk (a quarter of the total fall). In the opposite direction, changing patterns of temperature-related deaths contributed to higher life expectancy (accounting for > 20 % of the total rise in both females and males) but also higher lifespan inequality amongst older people. Most of the influence (about 80 %) was via moderate cold, but declines in risk at both moderate and extreme heat led to small rises in life expectancy.Our study points to the benefits of adopting risk-reduction strategies that aim, not only at modifying hazards and reducing exposure, but that also address socially-generated vulnerability among older people. This includes ensuring that lifespans lengthen primarily through increases in years lived in good health.

Transcriptome Analysis Revealed the Response Mechanism of Pomegranate to Salt Stress

Pomegranate (Punica granatum) is a well-known fruit tree species and a significant pioneer ecological species on saline–alkali land with moderate resistance to salt stress. To explore its response mechanism to salt stress could provide valuable insights into the molecular and physiological strategies plants employ to adapt and survive in high-salt environments. In this study, changes in physiological parameters and gene expressions were examined following salt treatment. After 72 h of salt treatment, change patterns of SOD and POD differed between high and low salt concentrations. Similar changes were found in the contents of proline and total soluble sugar. RNA-Seq analysis of fifteen samples detected 32,630 genes from the pomegranate genome data. A total of 6571 DEGs, including 374 TFs, were identified across different treatments. Six special modules and 180 hub genes were obtained by WGCNA analysis. Functional annotation highlighted signaling pathways and the accumulation of primary and secondary metabolites as significant pathways. These findings could reveal the salt tolerance mechanism in pomegranate leaves, offering a theoretical foundation for enhancing plant salt tolerance through genetic engineering.

The dependence structures between geopolitical risks and energy prices: New evidence from regional heterogeneity and quantile-on-quantile perspective

We construct GPR indices for six major regions and select three categories of energy markets. Utilizing a quantile-on-quantile connectedness approach and impulse response analysis, we investigate the changing patterns of connectedness between these variables under different levels of GPRs and various energy market conditions. Furthermore, we explore the intensity, direction, and duration of GPRs impacts on energy markets. Our findings reveal that the total connectedness tends to be minimal at intermediate quantiles (50 %)—approximately 20%—increasing significantly toward both higher (95 %) and lower quantiles (5 %), with an enhancement of approximately 125 %–250 %. The maximum total connectedness between GPRs and Oil, Coal, and Gas is 87.2 %, 90.9 %, and 86.5 %, respectively. Connectedness during periods of extremely high GPRs percentile (95 %) is 30 % greater compared to low quantiles (5 %). The impact of GPRs on Oil typically lasts about 3–5 months, with a shorter duration of around 3 months for Gas and a longer duration of approximately 5 months for Coal, which can be prolonged by major events. Our conclusions underscore the importance for policymakers and traders to monitor the evolving patterns of connectedness between GPRs and energy markets under changing conditions, ensuring comprehensive risk awareness and robust trading decisions.

Exploring emergent microservice evolution in elastic deployment environments

Microservices have become an important technology to enable the dynamic composition of large-scale self-adaptive systems. Although modern microservice ecosystems provide a variety of autonomous adaptation mechanisms, when focusing on the microservice itself, they can only account for changes in the sheer increase in workload volume. On the other hand, when workload patterns change, efficient treatment requires the intervention of DevOps experts to manually evolve the internal architecture of services. Given the need to quickly adapt systems to respond to changes, solely relying on DevOps to react to workload pattern changes becomes a bottleneck for future systems. To address this issue, we advance the concept of emergent microservices, that autonomously adapt and evolve their internal architectural composition to better handle changes in the pattern of incoming requests without human intervention. We demonstrate the effectiveness of our approach by exploring this novel concept in the context of a microservice-based Smart City platform.Editor’s note: Open Science material was validated by the Journal of Systems and Software Open Science Board.

ALTERNATIVE EXPLANATION OF FILLING THE ELECTRONIC LAYERS OF ATOMS OF CHEMICAL ELEMENTS

The article provides a new approach to the formation of periods in Mendeleev's periodic system. Reconfiguration of the periods in the Mendeleev table using the newly proposed formula and the newly proposed quantum states for the outer electron shells of atoms of chemical elements is proposed. Purpose of work: Further development of the alternative theory of creation of electronic shells of atoms of chemical elements in D.I.Mendeleev's table. Results and discussions. The following order of formation of electron layers is proposed: principle quantum number (n), then the quantum state of the electrons forming the electronic configuration of the subperiods (first and second), and only then the remaining quantum orbitals (s, d, f and p). First and second new quantum states and a new formula for calculating the number of electrons in the outer electron shell of element periods and subperiods were proposed. The new level of electronic counting (II) and the new quantum number proposed by us allow to change the understanding of the internal structure of chemical elements without changing the general appearance and order of arrangement of chemical elements in D.I.Mendeleev's table itself, and therefore its contents. An important advantage of the proposed alternative model is that it takes into account and relies on already known, classical data for most of its main operational characteristics and is an extension of this important topic for classical chemistry theory. Therefore, the change in the number of periods, the introduction of a new quantum number in the form of D.I.Mendeleev's table, outwardly it does not differ much, but requires the necessary additional explanation. Concept. The proposed alternative approach to the structure and electronic structure of atomic shells of chemical elements in the periods and groups of D.I.Mendeleev's periodic system was recently developed by the authors and has good prospects for development primarily in the following directions: - identification of possible patterns of changes in the characteristics of chemical and physical properties of elements; - development of an accompanying model of the electronic structure of electronic shells of atoms of chemical elements of the proposed alternative model.

Investigation the effect of Acceptance and Commitment Therapy (ACT) training on stigma and family functioning in family members of patients with psychiatric disorders: a randomized controlled clinical trial

BackgroundRegarding the prevalence and pervasiveness of psychiatric disorders, which significantly affect not only the patients themselves, but also their families, family therapy has emerged as a promising intervention. This research examined the effects of Acceptance and Commitment Therapy (ACT) on stigma and family functioning in family members of patients with psychiatric illnesses, demonstrating effectiveness in improving family functioning and coping strategies in the face of mental illness.MethodsThis randomized controlled clinical trial without blinding. Forty family members of patients with psychiatric disorders were randomly assigned to an intervention group (N = 20) or a control group (N = 20). The intervention group received ACT in eight weekly sessions, each lasting 90 min, while control group remained on a waiting list. Both groups were assessed at three time points: pre-intervention, post-intervention, and at a one-month follow-up. Data collection instruments included a demographic information questionnaire, a stigma assessment, and a family functioning measure. Data were analyzed using SPSS software version 23.ResultsA statistically significant difference was observed between the mean post-test and follow-up stigma scores of the intervention and control groups (P < 0.05). The intervention group’s mean scores showed a rising trend, whereas the control group’s mean scores showed a declining trend. This was evident from within-group comparisons of the mean post-test and follow-up stigma scores. Repeated measures ANOVA indicated that the pattern of change in stigma for the intervention group was significant, in contrast to control group, suggesting a reduction in stigma (P < 0.001).ConclusionIn light of the findings presented in this study, ACT emerges as a promising intervention for mitigating stigma, and enhancing the family functioning of individuals afflicted with mental disorders. To improve the generalizability of the study results, comparable studies using this therapy method should be undertaken on family caregivers of patients with mental illnesses.Iranian Registry of Clinical TrialsIRCT registration number: IRCT20190917044802N10.Registration date14/9/2023.

The study of the city of Rudny as a “heat island”

The annual increase in surface air temperatures contributes to climate change. This phenomenon is widespread over the entire surface of the Earth and is typical for any point of the planet. The purpose of this study was to identify patterns of changes in meteorological indicators in the city of Rudny, Kostanay region, Republic of Kazakhstan over the summer period 2018–2022. The scientific novelty of the work lies in the fact that for the first time the spatial distribution of the heat index in the territory of the city of Rudny was determined. To conduct the study, data from local automated weather stations were used, meteorological data was analyzed, compared for each year of the study, and the heat index was calculated. The reliability of the results is ensured by mathematical processing of daily empirical temperature and humidity data (calculation of the average for the day, the average for the month), coefficient of variation, coefficient of dispersion. The conducted research provides a clear description of climate changes in the city of Rudny, which can be used by municipal authorities to form measures to reduce the thermal impact on public health, heat loss in the housing and communal services system, and to improve air quality when planning urban infrastructure in the territory of the studied city.

China's “new era” in foreign policy: Explaining change under Xi Jinping

AbstractChina's supreme leader, Xi Jinping, has made fundamental changes to China's foreign policy, which have important implications for international security. What are the sources of Xi's foreign policy changes? Rather than assume that particular theoretical schools of international relations may provide the best explanations of foreign policy, we begin by observing that specific leaders' foreign policy preferences vary significantly. We infer characteristics of Xi's foreign policy preferences and methods based on his ideological statements, along with evidence from his domestic policies and habitually preferred methods of domestic rule. We find that these predicted characteristics imply policies that closely align with the revealed pattern of foreign policy change but also point out that foreign policy outcomes provide additional evidence about preferences that cannot be derived from ideological statements and domestic policy evidence.

Bond behavior between geopolymer recycled brick aggregate concrete and steel bars after exposure to high temperatures

The use of recycled brick aggregate (RBA) as the replacement for natural coarse aggregate in geopolymer concrete is an effective method for waste recycling. When the formed geopolymer recycled brick aggregate concrete (GRBC) is employed in structures, it may encounter the risk of fire. Whether the steel bars and GRBC can work together after a fire is the basis for structural safety and analysis. However, previous research on the bond behavior between GRBC and steel bars after exposure to high temperatures is still lacking. In this paper, pull-out tests on 50 GRBC and 50 ordinary recycled brick aggregate concrete (ORBC) were conducted to investigate the effects of temperature (20 °C, 200 °C, 400 °C, 600 °C, and 800 °C), and RBA replacement ratio (0 %, 25 %, 50 %, 75 %, and 100 %). The test results show that the failure pattern of GRBC specimens changes from splitting-pull-out failure to pull-out failure as the heating temperature increases. The bond strength decreases with the increase of temperature or RBA replacement ratio. When the temperature rises from 200 °C to 800 °C, the bond strength of GRBC pull-out specimens decreases by 11.54 %–72.33 % compared with the specimens at room temperature, and the decrease rate is lower than that of ORBC. The bond strength of GRBC specimens with a 100 % replacement ratio decreases by 46.34 %–53.74 % compared with those without replacement. The peak slip of GRBC specimens generally increases with increasing temperature or decreasing RBA replacement ratio. Based on the post-temperature test results and the room temperature model, suitable models for the bond strength and peak slip of GRBC after high temperatures were established. The predicted results of bond stress−relative slip curves were in good agreement with the test results. The findings of this study can provide a foundation for the application of GRBC, and provide a basis for its structural analysis after high temperatures.