Most nature and health research use the normalized difference vegetation index (NDVI) for measuring greenness exposure. However, little is known about what NDVI measures in terms of vegetation types (e.g., canopy, grass coverage) within certain analysis zones (e.g., 500 m buffer). Additionally, exploration is needed to understand how to interpret changes in average NDVI (e.g., per 0.1 increments) exposure in relation to changes in vegetation amount and types. In this study, we aimed to explore what vegetation types and amounts best explain the average NDVI and how changes in average NDVI values indicate changes in different vegetation coverages. We used spatial modeling to sample mean NDVI and percentages of vegetation for sample locations within the Greater Manchester case study area. We fitted linear, nonlinear, and mixed multivariate and univariate generalized additive models (GAMs) for multiple spatial scales to identify the relationships between NDVI and vegetation amount and types. Our results showed that the relationships between NDVI and individual vegetation types mostly follow nonlinear trends. We found that canopy and shrubs coverage exhibited a greater influence on mean NDVI exposure values than grass coverage at 300 and 500 m indicating that NDVI values are sensitive to certain types and amounts of vegetation within various buffer zones. We also identified increment in mean NDVI exposure values at lower, mid, and high ranges might be associated with varying changes in total greenspace percentage and individual vegetation types. For instance, at 300 m buffer, an increment of mean NDVI in the lower range (e.g., from 0.2 to 0.3) is associated with an about 17% increase in greenspace percentage. Overall, interpreting changes in NDVI values for urban greening interventions would require careful evaluation of the relative changes in types and quantities of vegetation for different buffer zones.