The integration of distributed power sources into the distribution network has changed the topology of traditional distribution networks, resulting in changes in fault characteristics, and brought severe challenges to conventional current protection of distribution network. This article proposes a protection method based on the comprehensive impedance of a new positive sequence fault component. Analyze the fault characteristics of positive sequence fault voltage and current during faults inside and outside the line area connected to different types of distributed power sources. The positive sequence fault components of voltage and current at both ends of the section are used to calculate the estimated line impedances. A novel comprehensive impedance is obtained by their subtraction. The ratio of comprehensive impedance to line impedance is constructed. The protection criterion for short circuit fault is given. The simulation experiments illustrate the effectiveness of proposed protection algorithm, not affected by the fault types, locations, permeabilities of distributed generations, has strong ability to withstand transition resistance.