Changes In Behavioral Measures Research Articles

Penerapan Pendekatan Kelompok dalam Konseling Remaja: Evaluasi terhadap Perubahan Perilaku

This study aims to evaluate the effectiveness of applying a group approach in counseling adolescents to address changes in their behavior. The research method used was quasi-experimental with a pre-test and post-test design to measure behavior changes before and after the group counseling intervention. The research sample consisted of 30 adolescents randomly selected from several high schools in city X using probability sampling methods. The group counseling intervention was conducted over 8 sessions, with each session lasting 90 minutes. Counseling topics included emotional control, communication skills, stress management, and confidence building. Data collection instruments included validated and reliable questionnaires, as well as direct observation by facilitators. Data obtained from the pre-tests and post-tests were analyzed using paired t-tests to determine if there were significant changes in adolescent behavior before and after the intervention. The data analysis results indicated significant positive changes in adolescent behavior after participating in group counseling. These changes included improvements in emotional control, better communication skills, more effective stress management, and increased self-confidence. Additionally, adolescents showed a more positive attitude toward themselves and their social environment.

A conciliatory and persuasive social campaign changes owner behavior to reduce cats' hunting

AbstractSolutions to the cats‐hunting‐wildlife environmental conflict could benefit from social science approaches. Our Theory of Planned Behavior questionnaire—informed by an elicitation survey of cat owners at veterinary clinics about their attitudes, norms, and beliefs regarding bringing their cats inside at night—surveyed 158 cat owners across 20 veterinarian clinics in four cities. It revealed that wildlife conservation was not influential on cat owner intention but veterinarians, cat safety, peers, and household members were. Thus, we designed a social marketing campaign with two treatments: (1) a veterinarian/cat safety message or (2) social/family norm message. Thirty‐four veterinary clinics received one of the two campaign posters or served as the control group. Customers (n = 510) received a “cat welfare” survey and then a pamphlet with the advocated message, and a follow‐up survey by email or telephone 3–6 weeks later (69% response rate). Campaign messaging significantly increased the number of cat owners who reported bringing their cats inside at night compared to the control group. The social/family norm message was most effective. Although rudimentary, the campaign generated measurable changes in cat owner intention and behavior. Conservation campaigns informed by co‐benefits for cat owners may reduce cats' hunting and be conciliatory ways of transcending environmental conflict.

Development and testing of a bespoke cultural intervention to support healthcare professionals with patients from a diverse background.

Development and test of a culturally sensitive intervention for rheumatology healthcare professionals (HCPs). Using a before and after study design, 15 HCPs were recruited to undertake the bespoke intervention from four National Health Service sites across England, in areas serving a diverse population. The intervention was evaluated using two validated outcomes: (i) Patient Reported Physician Cultural Competency (PRPCC); and (ii) Patient Enablement Instrument (PEI), measuring patients' perceptions of their overall healthcare delivery. Additionally, HCPs completed the COM-B questionnaire for capability (C), opportunity (O) and motivation (M) to perform behaviour (B), measuring behaviour change. Two hundred patients were recruited before HCPs undertook the intervention (cohort 1), and 200 were recruited after (cohort 2) from 15 HCPs; after exclusions 178 patients remained in cohort 1 and 186 in cohort 2. Sixty percent of patients identified as white in both recruited cohorts, compared with 29% and 33% of patients (cohorts 1 and 2, respectively) who identified as being of South Asian origin. After the intervention, the COM-B scores indicated that HCPs felt more skilled and equipped for consultations. No significant differences were noted in the average overall cultural competency score between the two cohorts in white patients (57.3 vs 56.8, P = 0.8), however in the South Asian cohort there was a statistically significant improvement in mean scores (64.1 vs 56.7, P = 0.014). Overall, the enablement score also showed a statistically significant improvement following intervention (7.3 vs 4.3, P < 0.001) in the white patients and in the South Asian patients (8.0 vs 2.2, P < 0.001). This novel study provides evidence for improving cultural competency and patient enablement in rheumatology settings.

The effects of probabilistic context inference on motor adaptation.

Humans have been shown to adapt their movements when a sudden or gradual change to the dynamics of the environment are introduced, a phenomenon called motor adaptation. If the change is reverted, the adaptation is also quickly reverted. Humans are also able to adapt to multiple changes in dynamics presented separately, and to be able to switch between adapted movements on the fly. Such switching relies on contextual information which is often noisy or misleading, affecting the switch between known adaptations. Recently, computational models for motor adaptation and context inference have been introduced, which contain components for context inference and Bayesian motor adaptation. These models were used to show the effects of context inference on learning rates across different experiments. We expanded on these works by using a simplified version of the recently-introduced COIN model to show that the effects of context inference on motor adaptation and control go even further than previously shown. Here, we used this model to simulate classical motor adaptation experiments from previous works and showed that context inference, and how it is affected by the presence and reliability of feedback, effect a host of behavioral phenomena that had so far required multiple hypothesized mechanisms, lacking a unified explanation. Concretely, we show that the reliability of direct contextual information, as well as noisy sensory feedback, typical of many experiments, effect measurable changes in switching-task behavior, as well as in action selection, that stem directly from probabilistic context inference.

Analisis Tingkat Kesulitan Guru Bimbingan Konseling dalam Memberikan Layanan BK di Sekolah Inklusif SMA Muhammadiyah Curup

The study aims to examine the implementation of Counseling Guidance (BK) services in an inclusive school, namely SMA Muhammadiyah Curup. This research is motivated by the need for ABK so that they can develop more optimally like other ordinary students. While ABK has problems with; the process of adjustment at school, school stigma on ABK is considered to reduce school quality, lack of ABK learning facilities, bullying behavior on ABK, and labeling report cards that read inclusive students. For this reason, BK teachers must be able to provide complex and specific BK services that are easily understood and implemented by ABK and ordinary. These students can unite ABK and ordinary students in learning.The research method used a descriptive qualitative approach with descriptive analysis, namely analyzing the problems of counseling teachers at SMA Muhammadiyah Curup, using in-depth interviews and observations of counseling teachers and students. For technical data validity with source and technique triangulation, then the data is verified and displayed descriptively.The research results show that: First; BK services with a classical format can be applied to all students, Second; Counseling for children with mental retardation and mild autism requires special training on measurable changes in behavior, with reinforcement or rewards. Third; the consistency of school collaboration with parents is very necessary in order to maintain independent behavior that has been formed with empathy from all parties. Fourth; It is easier for BK teachers to make ABK independent with the same disorder than those with various disorders. Fifth; BK teachers don't understand sign language, Braille writing, and other unique things about ABK.

Skin cancer screening and sun safety education program for high school students in southern California.

e22505 Background: Decreasing unprotected exposure to ultraviolet (UV) radiation during childhood can significantly decrease the risk of developing skin cancer as an adult. School-based sun safety curricula have demonstrated efficacy in teaching young adults about the harms of prolonged, unprotected UV exposure and have been effective in increasing safety practices. This project provided a 50-min sun safety curriculum to high school students at a public high school in San Diego, CA just prior to the summer break in 2022. The curriculum addressed skin cancer risk factors, skin protection methods, the benefits of limiting lifetime UV exposure, and methods for performing a skin self exam. The study objective was to assess sun safety knowledge before and after the class, and measure behavior changes three months thereafter when students returned from summer break. Methods: The sun safety classes were taught in groups of 40-60 students across six class periods in June 2022. Students were asked to complete an anonymous pre-participation online survey assessing their knowledge of common skin cancer types and skin cancer risk factors. Students were taught the curriculum over 45 minutes with 5 minutes reserved for questions. Two follow-ups surveys were conducted with the students, one at the end of the class period and a second follow-up three months later. Follow-up surveys assessed retention of knowledge and changes in sun safety behavior. Students had the option of providing a cell phone number so they could be contacted to participate in the second follow-up survey. Results: The curriculum was taught to nine classes of approximately 300 students in a single day across six class periods. A total of 206 students completed the pre-participation survey. At the first follow-up, 95.1% of students completed the post-participation survey and students showed significant improvement in knowledge of common skin cancer types (12.6% pre-participation to 68.9% post-participation), skin cancer risk factors (11.2% pre-participation to 16.8% post-participation), and skin cancer prevention methods (22.8% pre-participation to 45.9% post-participation). For the second follow-up, 128 students provided contact information and the survey had a response rate of 71.5%. After 3 months, students demonstrated retention of knowledge of skin cancer types and risk factors. A majority (87.2%) of students indicated that their use of sunscreen had increased and 57.4% indicated that their use of sun protective barriers had increased over the summer because of this course. Conclusions: This pilot course demonstrates that targeted sun safety education for teenagers before summer break can significantly increase sun safety awareness, adoption of protective behaviors, and knowledge about skin cancer. Such an intervention can promote skin cancer awareness at a young age where behavior changes can decrease lifetime risk of skin cancer.

Orientation selective stimulation with tetrahedral electrodes of the rat infralimbic cortex to indirectly target the amygdala.

Deep brain stimulation (DBS) is a rapidly developing therapeutic intervention with constantly expanding neurological and psychiatric indications. A major challenge for the approach is the precise targeting and limitation of the effect on the desired neural pathways. We have introduced a new approach, orientation selective stimulation (OSS) that allows free rotation of the induced electric field on a plane when using a probe with three parallel electrodes forming an equilateral triangle at the tip. Here, we expand the technique by introducing a tetrahedral stimulation probe that enables adjustment of the primary electric field direction freely at any angle in a 3D space around the stimulating probe. OSS in 3D will enable better targeting of the electric field according to the local brain anatomy. We tested its utility in a rat model of DBS for treatment-resistant depression. The stimulation directed to the subgenual anterior cingulate cortex (sgACC) has yielded dramatic improvement in individual patients suffering from therapy resistant depression, but no consistent benefit in larger series. This failure has been ascribed to the challenging anatomy of sgACC with several crossing neural tracts and individual differences in the local anatomy. We stimulated infralimbic cortex (IL), the rat analog of sgACC, and recorded local electrical responses in amygdala (AMG) that is monosynaptically connected to IL and plays a central role in emotional states. We further traced AMG-IL connections using a viral vector and tractography using diffusion magnetic resonance imaging (MRI). Finally, we mimicked the clinical situation by delivering sustained 130 Hz stimulation at IL at the most effective field orientation and followed changes in resting-state functional connectivity with IL using functional MRI. To help interpretation of responses in functional connectivity, we stimulated only the left IL, which we did not expect to evoke measurable changes in the rat behavior. The AMG evoked responses depended systematically on the IL stimulation field orientation and yielded the maximum response in near vertical field orientation in accordance with tractography. Sustained 130 Hz stimulation at a field orientation yielding the strongest AMG evoked responses increased functional connectivity between IL and AMG on the stimulation side. These findings suggest that OSS in 3D provides a new approach to optimize the DBS for every individual patient with a single stimulation probe implantation.

Penerapan Teori Behaviorisme dalam Pembelajaran

This article examines the application of behaviorism to the study of learning. This article employs a literature study methodology to seek and discover solutions through a literature evaluation of books, journals, and researchers' direct observations. The study's findings demonstrate that the behaviorist perspective acknowledges the significance of stimulus input and response output. Behaviorism is a learning theory that stresses the study of behavior formation based on the relationship between observable stimuli and response and awareness and mental constructions. In conclusion, behaviorism learning theory contrasts with cognitive theory, which contends that the learning process is an invisible mental process. The behaviorist learning theory lays a strong emphasis on observable, measurable, and quantifiable behavioral changes as learning outcomes.&#x0D; Keywords: Understanding, Implementation, Behaviorism Theory&#x0D;

Do ADHD Treatments Improve Executive Behavior Beyond Core ADHD Symptoms in Adults? Evidence From Systematic Analysis of Clinical Trials.

We sought to understand the effect of current treatments for attention deficit hyperactivity disorder (ADHD) on executive functioning deficits, which are often comorbid with ADHD, via a systematic analysis of adult ADHD treatment studies evaluating change in behavioral measures beyond the core symptoms of Diagnostic and Statistical Manual of Mental Disorders ADHD. The standardized mean difference for behavioral measures of executive functioning was determined from controlled trials of adults with ADHD and compared with effects on core ADHD symptoms. Several studies of atomoxetine revealed small to large standardized mean differences. Nonreplicated studies revealed small to medium effects for triple-bead mixed amphetamine salts, lisdexamfetamine, and forms of cognitive behavioral therapy. Proportional effect versus core ADHD symptoms ranged from 0.78 to 1.16 for atomoxetine, and from 0.65 to 1.44 across all the studies. ADHD treatments have effects on executive functioning behavior beyond core ADHD symptoms in adults. Clinicians can measure and treat this morbidity using available clinical tools.

Ethanol blocks a novel form of iLTD, but not iLTP of inhibitory inputs to VTA GABA neurons.

The ventral tegmental area (VTA) is an essential component of the mesocorticolimbic dopamine (DA) circuit that processes reward and motivated behaviors. The VTA contains DA neurons essential in this process, as well as GABAergic inhibitory cells that regulate DA cell activity. In response to drug exposure, synaptic connections of the VTA circuit can be rewired via synaptic plasticity-a phenomenon thought to be responsible for the pathology of drug dependence. While synaptic plasticity to VTA DA neurons as well as prefrontal cortex to nucleus accumbens GABA neurons are well studied, VTA GABA cell plasticity, specifically inhibitory inputs to VTA GABA neurons, is less understood. Therefore, we investigated the plasticity of these inhibitory inputs. Using whole cell electrophysiology in GAD67-GFP mice to identify GABA cells, we observed that these VTA GABA cells experience either inhibitory GABAergic long-term potentiation (iLTP) or inhibitory long-term depression (iLTD) in response to a 5 Hz stimulus. Paired pulse ratios, coefficient of variance, and failure rates suggest a presynaptic mechanism for both plasticity types, where iLTP is NMDA receptor-dependent and iLTD is GABAB receptor-dependent-this being the first report of iLTD onto VTA GABA cells. As illicit drug exposure can alter VTA plasticity, we employed chronic intermittent exposure (CIE) to ethanol (EtOH) vapor in male and female mice to examine its potential impact on VTA GABA input plasticity. Chronic EtOH vapor exposure produced measurable behavioral changes illustrating dependence and concomitantly prevented previously observed iLTD, which continued in air-exposed controls, illustrating the impact of EtOH on VTA neurocircuitry and suggesting physiologic mechanisms at play in alcohol use disorder and withdrawal states. Taken together, these novel findings of unique GABAergic synapses exhibiting either iLTP or iLTD within the mesolimbic circuit, and EtOH blockade specifically of iLTD, characterize inhibitory VTA plasticity as a malleable, experience-dependent system modified by EtOH.

Content validity study: a gamification model to drive behavior change in defeating coronavirus disease 2019 pandemic

&lt;span&gt;Gamification refers to transforming the environment to become more game-like to produce a positive experience. In this study, the researchers developed a gamification model, namely the GAMEBC model, to drive behavior change through a health awareness campaign in defeating the coronavirus disease 2019 (COVID-19) pandemic. The GAMEBC model was developed based on the self-determination theory (SDT) and gamification design literature. The GAMEBC model in this study involves four elements: competence, relatedness, autonomy, and engagement. Each element includes criteria that drive behavior change in health awareness campaigns. However, studies that validated the gamification model elements are limited, specifically to drive behavior change. Therefore, the content validity of the GAMEBC model instrument was carried out, and the analysis was based on thirteen expert reviews. The mean value and inter-rater agreement approach were implemented to examine the content validity ratio (CVR), item content validity index (I-CVI), and scale content validity index (S-CVI). The expert evaluation approach was implemented to review the GAMEBC model in terms of relevance and clarity. The data were analyzed using descriptive analysis. As a result of this work, we formulated an instrument that can be used to model and measure behavior change through the gamification approach in health awareness campaigns.&lt;/span&gt;

Topographic organization of the human caudate functional connectivity and age-related changes with resting-state fMRI.

The striatum is postulated to play a central role in gating cortical processing during goal-oriented behavior. While many human neuroimaging studies have treated the striatum as an undivided whole or several homogeneous compartments, some recent studies showed that its circuitry is topographically organized and has more complex relations with the cortical networks than previously assumed. Here, we took a gradient functional connectivity mapping approach that utilizes the entire anatomical space of the caudate nucleus to examine the organization of its functional relationship with the rest of the brain and how its topographic mapping changes with age. We defined the topography of the caudate functional connectivity using three publicly available resting-state fMRI datasets. We replicated and extended previous findings. First, we found two stable gradients of caudate connectivity patterns along its medial-lateral (M-L) and anterior-posterior (A-P) axes, supporting findings from previous tract-tracing studies of non-human primates that there are at least two main organizational principles within the caudate nucleus. Second, unlike previous emphasis of the A-P topology, we showed that the differential connectivity patterns along the M-L gradient of caudate are more clearly organized with the large-scale neural networks; such that brain networks associated with internal vs. external orienting behavior are respectively more closely linked to the medial vs. lateral extent of the caudate. Third, the caudate's M-L organization showed greater age-related reduction in integrity, which was further associated with age-related changes in behavioral measures of executive functions. In sum, our analysis confirmed a sometimes overlooked M-L functional connectivity gradient within the caudate nucleus, with its lateral longitudinal zone more closely linked to the frontoparietal cortical circuits and age-related changes in cognitive control. These findings provide a more precise mapping of the human caudate functional connectivity, both in terms of the gradient organization with cortical networks and age-related changes in such organization.

Effect of modified programming parameters on sound field thresholds, speech perception and CAEP among children using CP802 processor

Optimizing and validating programming parameters of Thresholds(T) and most comfortable levels(C) is very important in young children using a cochlear implant who may not be able provide behavioral responses. The present study attempts to describe the changes in T/C level with behavioral and Cortical Auditory Evoked Potentials (CAEP) responses. Twenty participants using CI24RE (ST) implant with CP802 speech processor participated in the study. Three experimentally ‘sham’ programs were created by a) decreasing T levels, b) raising T levels or c) decreasing C levels in the ‘everyday’ program. Sound field thresholds and speech perception at 50dBHL were measured for all experimental and everyday programs. Acoustically evoked CAEP measures, namely thresholds for three different stimuli of/ba/,/da/and/ga/, along with amplitude and latency at 80dBnHL were recorded for all programs. The results indicated that modification of T levels did not have significant effect on CAEP threshold, latency, amplitude as also on behavioral measures of sound field thresholds and speech perception. However, reduction of C levels resulted in significantly poor sound field thresholds, speech perception as well as CAEP thresholds. Furthermore, it was found that there was a significant correlation between behavioral measures of sound field threshold and speech perception with CAEP measures. Thus, from the present study it may be concluded that behavioral and CAEP responses can be used as indicator to reflect changes in C levels resulting changes in behavioral measures in users of CP802 speech processors.

Measuring behavior change technique delivery and receipt in physical activity behavioral interventions.

Research on physical activity behavioral support has mainly focused on measuring the absence or presence of behavior change techniques (BCTs) delivered by a counselor. We present a method to measure BCT delivery and receipt in physical activity behavioral support interventions. The method was developed and tested using transcripts from behavior change counseling sessions delivered as part of a theory- and evidence-based physical activity intervention for adults with disabilities. Using existing methods, a new method was developed to code counselor and clients' verbal statements (BCTs and other statements). Two coders independently coded 30 transcripts of audio-recorded counseling sessions. Interrater reliability was assessed using percentage agreement and Prevalence Adjusted Bias Adjusted Kappa (PABAK). Forty-eight codes were developed for counselor statements (35 BCT delivery and 13 other statements) and 46 codes for client statements (34 BCT receipt and 12 other statements). The average interrater reliability was considered nearly perfect for the counselor statements (84% agreement; PABAK = .98) and client statements (86% agreement; PABAK = .98). The BCT delivered and received were most frequently related to Goals and Planning (counselor:36%, client:35%), Support Strategies (counselor:21%, client:17%) and Self Belief (counselor:13%, client:24%). This study presents a reliable coding method to measure BCT delivery and receipt in physical activity behavioral support interventions. The method can be used to enhance intervention fidelity assessment and study interactions between counselors and clients with and without disabilities. Measuring and evaluating BCT delivery and receipt can provide new insights into what types of behavioral support work best under which circumstances. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

A double-blind study assessing the impact of orbitofrontal theta burst stimulation on goal-directed behavior.

Patients with disorders of compulsivity show impairments in goal-directed behavior, which have been linked to orbitofrontal cortex (OFC) dysfunction. We recently showed that continuous theta burst stimulation (cTBS), which reduces OFC activity, had a beneficial effect on compulsive behaviors both immediately and at 1 week follow-up compared with inhibitory TBS (iTBS). In this same sample, we investigated whether two behavioral measures of goal-directed control (devaluation success on a habit override task; model-based planning on the two-step task) were also affected by acute modulation of OFC activity. Overall, model-based planning and devaluation success were significantly related to each other and (for devaluation success) to symptoms in our transdiagnostic clinical sample. These measures were moderately to highly stable across time. In individuals with low levels of model-based planning, active cTBS improved devaluation success. Analogous to previously reported clinical effects, this effect was specific to cTBS and not iTBS. Overall, results suggested that measures of goal directed behavior are reliable but less affected by cTBS than clinical self-report. Future research should continue to examine longitudinal changes in behavioral measures to determine their temporal relationship with symptom improvement after treatment. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Supplemental Material for Measuring Behavior Change Technique Delivery and Receipt in Physical Activity Behavioral Interventions

Supplemental Material for Measuring Behavior Change Technique Delivery and Receipt in Physical Activity Behavioral Interventions

MiRNA-124-3p targeting of LPIN1 attenuates inflammation and apoptosis in aged male rats cardiopulmonary bypass model of perioperative neurocognitive disorders.

Perioperative neurocognitive disorder (PND) is recently recommended to define the cognitive decrease during the perioperative period. However, the disease's underlying mechanisms remain unclear. MicroRNAs (miRNAs) are noncoding RNAs that play a vital role in regulating neuroregeneration and neuronal apoptosis. In this study, miR-124-3p was significantly reduced in the PND rat model after a cardiopulmonary bypass (CPB) procedure. MicroRNA-124 (miR-124)-3p-overexpressed lentivirus was constructed and injected via the intracerebroventricular method before CPB. Morris Water Maze test (WMW) and the Open-Field test (OFT) were used to measure behavior changes, data shows decline of cognitive function of rats after CPB. PND rats expressed higher Aβ and p-Tau Protein by using immunohistochemistry (IHC) analyses and Enzyme-Linked Immune Sorbent Assay (ELISA). Moreover, the results of IHC, ELISA, Western Blot analysis (WB) and Terminal-deoxynucleotidyl Transferase Mediated Nick End Labeling Assay (TUNEL) showed CPB procedure induced inflammation and apoptosis in rats with PND. The data also revealed the protective function of miR-124-3p overexpression against PND in relieving inflammation, cell apoptosis, and alleviating repaired cognitive function. Moreover, miR-124-3p was predicted by directly targeting LPIN1. This study gives a novel viewpoint that miR-124-3p could improve the state of PND via modulating LPIN1, therefore providing a new strategy for preventing and treating PND in a preclinical application.

Association of Cannabis Use and Neurodevelopment Among Adolescents

Source: Albaugh MD, Ottino-Gonzalez J, Sidwell A, et al Association of cannabis use during adolescence with neurodevelopment [published online ahead of print June 16, 2021]. JAMA Psychiatry. doi:10.1001/jamapsychiatry.2021.1258Investigators from multiple institutions reviewed data from a longitudinal study to assess the association between cannabis use during adolescence and cerebral cortical thickness development as measured using MRI. Participants were enrolled in the IMAGEN study, conducted across 8 European sites, when they were approximately 14 years old. Using a standard protocol, MRI scans were obtained of the adolescents’ brains at enrollment and a 5-year follow-up visit. In addition, at baseline and at follow-up, study participants completed the European School Survey Project on Alcohol and Other Drugs (ESPAD), in which lifetime use of alcohol, nicotine, and cannabis is self-reported using a 7-point scale with usage ranging from “never” to “>40 times.” Only youths who reported never using cannabis at baseline and had baseline and 5-year data were included in the present study. At the 5-year follow-up, participants also completed the Barratt Impulsiveness Scale, a 30-item self-report that assesses 3 domains of impulsiveness (attentional, non-planning, and motor). Alcohol consumption was estimated at baseline and 5-year follow-up with the Alcohol Use Disorders Identification Test Consumption scale.Cross-sectional regression models were used to assess the association between lifetime cannabis use and local cortical thickness. Longitudinal models were used to identify areas of accelerated age-related cortical thinning associated with cannabis use and to evaluate the association between the 3 domains of impulsiveness as measured by the Barratt Impulsiveness Scale.A total of 799 youths who were cannabis-naïve at baseline were included in the analyses. Mean age of these participants at baseline was 14.0 ±0.4 years, and 56.3% were female. At the 5-year follow-up, 208 participants (26.0%) reported 1-9 lifetime uses of cannabis, and 161 (20.2%) reported 10 to >40 uses. On cross-sectional analysis, there was a dose-dependent, statistically significant negative association between cortical thickness in the left prefrontal and right prefrontal cortices and lifetime cannabis use assessed at the 5-year follow-up. No statistically significant relationships were found between lifetime cannabis use and cortical thickness on baseline MRI results, suggesting that differences observed at follow-up did not precede cannabis use. On longitudinal analysis, statistically significant associations between accelerated age-related thinning in both the left and right prefrontal cortices were found. There was no significant difference in the effects of cannabis on cortical thickness between females and males in either the cross-sectional or longitudinal analyses. Cannabis-related cortical thinning in the right dorsomedial prefrontal cortex was significantly associated with more attentional impulsiveness as measured by the Barratt Impulsiveness Scale.The authors conclude that cannabis use during adolescence was associated with altered neurodevelopment.Dr Doolittle has disclosed no financial relationship relevant to this commentary. This commentary does not contain a discussion of an unapproved/investigative use of a commercial product/device.Cannabis use has become more popular and socially accepted in recent years. Many states have decriminalized marijuana use and expanded licensing for dispensaries.1 Nearly 50% of adolescents consider marijuana to be easily accessible, and 28% believe it to have no or low health risks.1 Nearly 1 in 10 persons older than 12 years of age has used marijuana within the past month.2 Large studies of marijuana derivatives, such as tetrahydrocannabinol and cannabidiol, have demonstrated improvement in a range of medical conditions, such as chemotherapy-related nausea, spasticity in multiple sclerosis, and chronic pain.3,4 As marijuana becomes more widely accepted, however, its deleterious effects are often overlooked. This is especially important among adolescents, whose cerebral cortex has not yet fully matured.5 In fact, the current authors describe thinning of the cerebral cortex of adolescent brains based on the cumulative dose of marijuana ingested. In addition, these anatomic effects are associated with a measurable behavioral change: attentional impulsiveness.While the decriminalization of marijuana has resulted in important legal reform, marijuana is best regarded as a drug, akin to alcohol. Use by adolescents ought to be discouraged, except when its medical benefit exceeds its potential harmful effect. While the investigators in the current study do not address the impact of marijuana beyond the 5-year follow-up, other large population studies highlight the association of marijuana use and harmful outcomes, such as respiratory problems, increased depression and anxiety, impaired executive function, poor school performance, and poverty.6,7The current study is the largest longitudinal study of its kind, making an important contribution to ongoing debate of marijuana’s harm and efficacy. Despite marijuana’s increasing popularity, pediatric caregivers should continue to advise caution.Marijuana use among adolescents is associated with cortical thinning and increased impulsiveness.

Learning by (virtually) doing: Experimentation and belief updating in smallholder agriculture

In much of sub-Saharan Africa, soil quality heterogeneity hampers farmer learning about the returns to different inputs. This may help explain why relatively few farmers in the region use improved inputs. We study how Kenyan farmers respond to an interactive app that enables them to discover the returns to different inputs on a virtual farm that is calibrated to resemble their own. Farmers update both their beliefs and their behaviors after engaging with the virtual learning app. We measure beliefs by eliciting probability distributions and use an incentive-compatible experiment to measure behavior change. The experiment gave participants an input budget that they could allocate across farm inputs. After playing several virtual seasons on the app, they could update these allocations. Farmers revise their input allocations along several dimensions after the virtual learning experience. To support our interpretation that these adjustments stem from real learning, we show that farmers with the highest predicted returns to lime—an unfamiliar input in this region—increase their lime orders more than others. Our results suggest that engagement with a personalized virtual platform can induce real learning and enhance farmers’ beliefs and technology choices.

Structural stability and microscale behaviors of the fortress wall from the sixth century Baekje Kingdom in ancient Korea

The Gongsanseong Fortress in Gongju, Republic of Korea, is one of the most essential remains for historical research of Baekje Kingdom, and reinforces on the fortress wall has continuously been implemented since the sixth century to present. Through visual inspections of the fortress ramparts, sections in which structural deformations have occurred, and then they were classified by morphological characteristics based on lithofacies that compose the ramparts, shape of each rock, and construction method. Also, automatic sensors that can measure behavior changes of the ramparts, and the surrounding environment were installed to monitor microscale movements of the ramparts and changes in the surrounding microclimate. As a result, damages were shown intensively on the ramparts that retain specific morphological characteristics, and it has been discovered that, even for the ramparts located in an identical environment, morphological characteristics affect damages and structural deformations of the ramparts because of behavior changes for minutes. Such changes in behavior can be classified based on reversibility and predictability, and different management schemes must be applied based on behavior change patterns. If we continuously operate and develop this monitoring system, it is expected to be meaningfully utilized in efficient maintenance of the cultural heritage of the ramparts.